SBGMD

Mom, nephrologist, internist, poet, artist, Patient advocate, protector and lover of kidney health and the preservation thereof! Tweets are my own

[SBGMD @KidneyReal]

@cnnbrk Mask up: Protect the kidneys of everyone you love including yourself from COVID19 https://t.co/4gdmARrP30

[AJKD @AJKDonline]

A Patient With HIV and Nephrotic Range Proteinuria: A Quiz

What are the differences between HIV-associated immune complex kidney disease (HIVICK) and HIV-associated nephropathy (HIVAN)?

https://t.co/h7sCcRwSAb (FREE)

@SaynaNorouzi @zainabo87 @uofcneph

[SBGMD @KidneyReal]

Hyperuricemia➡️Endothelial dysfunction ➡️ RAAS activation. #chess #checkmate #nephrocentric #forest #MedTwitter #poetry #bigpicture #Microscopy #art urate lowering therapy

[SBGMD @KidneyReal]

@edgarvlermamd @brian_rifkin 👏🎉

[Edgar V. Lerma 🇵🇭 @edgarvlermamd]

Decision support for PICC Line placement in patients with CKD ca. 2023
#Nephpearls #VascularAccessPearls

#VisualGraphic by @brian_rifkin

👉🏼 https://t.co/j3ur8VgWds

[Edgar V. Lerma 🇵🇭 @edgarvlermamd]

Acute Hypercalcemia: Treatment
#Nephpearls

👉🏼 https://t.co/bhiCaJwgDh

[SBGMD @KidneyReal]

Shout out to all the children who already want to be doctors & will do it! Hurry: save us from this looming physician shortage crisis. We believe in you! Much love, prayers & blessings!🤗

[SBGMD @KidneyReal]

Wow.

[Richard J. Glassock @GlassockJ]

My teeth grate whenever I hear of an “epidemic” of non-communicable diseases (NCD; like CKD, Autism or Alzheimer’s disease). The frequency of NCD in any given population can be decided by definitions (labels) and changes in how the disease is searched for (testing, screening )

[ASN Publications @asnpublications]

How do you treat challenging cases of antibody-mediated glomerular diseases? This #ASNCJASN article explains the options, their efficacy, and possible future directions for care. https://t.co/1efijqb6l4

[Sanjeev Sethi @SethiRenalPath]

Membranous nephropathy has undergone a paradigm shift due to the discovery of unique MN antigens.

MN has gone from idiopathic to ➡️ primary vs. secondary ➡️ where an antigen can be detected in ~80% of MN.

This is a comprehensive review of each antigen.

https://t.co/RJFApwsvG0

[SBGMD @KidneyReal]

👏👇never forget COL4A3 & COL4A4 located on chromosome 2 and what they will do. While paying homage to the classic X-linked inheritance involving COL4A5 that sometimes prefers to keep the girls alive. #poetic #nephrocentric #renasight

[Arkana Laboratories @arkanalabs]

The immunofluorescence image is that of an Alport panel. The red staining highlights the alpha 2 subunit of collagen type IV while the green staining is that of the alpha 5 subunit of collagen type IV. The image shows segmental loss of the alpha 5 staining of type IV collagen along the glomerular basement membranes compatible with Alport syndrome. Alport syndrome is an inherited disease secondary to mutations in the alpha 3, 4, and 5 subunits of type IV collagen. The most common form of the mutation, comprising approximately 65-85% of mutations, occurs via X-linked inheritance and involves the COL4A5 gene. Interestingly, with this form of Alport syndrome, the nature of the mutation can have a significant influence on the phenotype in males while the disease in females is dependent not only the nature of the mutation but the degree of X-inactivation. Other forms of the disease demonstrate autosomal inheritance (dominant as well as recessive forms) and are secondary to mutations in COL4A3 and COL4A4 located on chromosome 2. By electron microscopy, typical features of the disease include multilamellation, splitting, and scalloping of the glomerular basement membranes. Additionally, the basement membranes can show areas of marked attenuation as well as areas of thickening typically with abrupt changes between the two. Ultimately, genetic testing is required for a confirmation of the underlying mutation.

#renalpath #kidneypath #pathology #renal #pathX

[Arkana Laboratories @arkanalabs]

The immunofluorescence image is that of an Alport panel. The red staining highlights the alpha 2 subunit of collagen type IV while the green staining is that of the alpha 5 subunit of collagen type IV. The image shows segmental loss of the alpha 5 staining of type IV collagen along the glomerular basement membranes compatible with Alport syndrome. Alport syndrome is an inherited disease secondary to mutations in the alpha 3, 4, and 5 subunits of type IV collagen. The most common form of the mutation, comprising approximately 65-85% of mutations, occurs via X-linked inheritance and involves the COL4A5 gene. Interestingly, with this form of Alport syndrome, the nature of the mutation can have a significant influence on the phenotype in males while the disease in females is dependent not only the nature of the mutation but the degree of X-inactivation. Other forms of the disease demonstrate autosomal inheritance (dominant as well as recessive forms) and are secondary to mutations in COL4A3 and COL4A4 located on chromosome 2. By electron microscopy, typical features of the disease include multilamellation, splitting, and scalloping of the glomerular basement membranes. Additionally, the basement membranes can show areas of marked attenuation as well as areas of thickening typically with abrupt changes between the two. Ultimately, genetic testing is required for a confirmation of the underlying mutation.

#renalpath #kidneypath #pathology #renal #pathX

[Arkana Laboratories @arkanalabs]

A sample from the pathology teaching slide set on Membranous Nephropathy, jointly prepared by Arkana Laboratories and @goKDIGO. https://t.co/KwXMfV3nTh

#KDIGO #pathology #renal #renalpath #pathX #kidneypath #pathtwitter

[SBGMD @KidneyReal]

@arkanalabs Neutrophils aggregate
Dominate
To attempt to annihilate
Tubular peace
Hopefully renal resilience will ultimately prevail
#renal #nephrocentric #poetry #MedTwitter

[Roger Rodby @NephRodby]

Future @Rush_Nephrology fellow Dan Moreno giving his senior presentation on about as difficult a topic that a resident could tackle. 👏👏👏👏👏. And for someone who prides himself on great titles, I cannot believe I never thought of this one ! Go Dan! @RushDOIM.

[SBGMD @KidneyReal]

@sijiezheng @NephRodby @Rush_Nephrology @RushDOIM Gotta go grab my shades!😎

[SBGMD @KidneyReal]

Hallelujah and amen!

[So Choose @GraceAndMercy_7]

The mountains quake at him, and the hills melt, and the earth is burned at his presence, yea, the world, and all that dwell therein. The Lord is good, a strong hold in the day of trouble; and he knoweth them that trust in him.
Nahum 1:5&7
https://t.co/AIq4Jxwthd

[Roger Rodby @NephRodby]

Little will impact the future of nephrology more than this story, as it continues to play out. #nkfclinicals

[SBGMD @KidneyReal]

🩷

[SBGMD @KidneyReal]

March is #NationalKidneyMonth and I made these for 3 nephrologists dear to me 💗. https://t.co/9tofLDe2Gc

[SBGMD @KidneyReal]

😎

https://t.co/Cesn8kTM6B