Topher Kinsella

CEO of Watershed Therapeutics, Author or The Hidden WOMBAT, General surgeon, Stanford Biodesign Alumnus

[Topher Kinsella @KinsellaTopher]

@WillManidis If you can Build, you must, for all of civilizational progress depends on it.
If you cannot build, then improve.
If you cannot improve, then repair.
If you cannot repair, maintain.
If you cannot maintain, make it no worse.
If you destroy, Civilization is not for you.

[Topher Kinsella @KinsellaTopher]

@k1rallik this is the plot of PIG
https://t.co/gqzImkYaDw

[Topher Kinsella @KinsellaTopher]

@FischerKing64 lies hide behind abstractions. Crime stats are such. So was the "inflation index"

[Topher Kinsella @KinsellaTopher]

@sivori i really like the idea. neighborly.

[Topher Kinsella @KinsellaTopher]

@realpeteyb123 he acts fragile and that makes no sense

[Topher Kinsella @KinsellaTopher]

For the truly poor, the lottery is the only low-cost entry into an asymmetrical upside event they will ever see. What else are they going to do, put $5 in the bank and watch it compound?

[Topher Kinsella @KinsellaTopher]

@tqbf This is a law of the universe, as startups go from multi-functional Stars to laser-focused single-function Stripes. Will never change, is mandated, and weirdly good.

[Topher Kinsella @KinsellaTopher]

@x_armand There’s a paradoxical bounce that’s complicated. Anhedonia leads to dopamine-seeking behaviors. Alcohol (in a subset of population) is a stimulant and dopamine release.

https://t.co/1FNC1sAYLU

[Topher Kinsella @KinsellaTopher]

@QiaochuYuan If either was exponential, yes. So likely both are saturated, and now we’re flitting about taste

[Topher Kinsella @KinsellaTopher]

@AJA_Cortes “Drug companies don’t sell cures because they want to keep you sick” people in shambles.

[Topher Kinsella @KinsellaTopher]

@KlendathuCap This clue that this is good is that the finding is universal. It’s the mechanism by which traits are aggressively selected for in the individual (by female preference) and then distributed throughout future descendants (by male preference).

[Topher Kinsella @KinsellaTopher]

@staysaasy Interesting parallels to biology. It works, tested, iterated, refined for millions of years. You don’t understand it but it is understandable.

[Topher Kinsella @KinsellaTopher]

@jakozloski This serves a useful function. Female selection drives advancement, male selection drives distribution.

[Topher Kinsella @KinsellaTopher]

@Hitchslap1 General statements about the population don’t make any sense. Like making general statements about real estate market - the reality on the ground is very different in different segments.

[Topher Kinsella @KinsellaTopher]

@xwanyex Build > improve > repair > maintain > don’t make worse. Then several layers of hell until you get to the dividers, destroyers

[Topher Kinsella @KinsellaTopher]

@escapefrommelos This can only work if paired with liability for the judges - if anything less than the maximum is given and a crime recurred within the maximum time window, judge is criminally liable

[Topher Kinsella @KinsellaTopher]

@realpeteyb123 Deflation, like the future, will be unevenly distributed. Insane amounts of retail cash will go to zero. The truth will out.

[Topher Kinsella @KinsellaTopher]

@WillManidis If you can Build, you must, for all of civilizational progress depends on it.
If you cannot build, then improve.
If you cannot improve, then repair.
If you cannot repair, maintain.
If you cannot maintain, make it no worse.
If you destroy, Civilization is not for you.

[Topher Kinsella @KinsellaTopher]

@Alexfeinberg @BowTiedBull @nntaleb writes about this. If one surgeon looks like he’s from central casting and the other looks like an overweight balding butcher, the odds that the butcher is incompetent are zero. The odds that the beautiful surgeon is incompetent are never zero.

[Topher Kinsella @KinsellaTopher]

@sivori @iSpoogeDaily Delightful descent of tone as he gets to E1

[Topher Kinsella @KinsellaTopher]

@owenbroadcast Eating the same food as the kid repeatedly in front of them solves the riddle.