Konstantin Roeder

Lecturer (Assist. Prof.) in Molecular Biochemistry
KCL

[Konstantin Roeder @KoRoeder]

#Postdoc opportunity to join my group at #KCL to work on RNA modelling for 2 years (+1 year pot. extension). #CompChem #ChemPostDoc #PostDocJobs #RNA Apply by 17th September!

https://t.co/V6ccgnw1oH

[Konstantin Roeder @KoRoeder]

@ProfSyK Thank you!

[Konstantin Roeder @KoRoeder]

Finishing the year on a high - a new job and an accepted paper. 🥳
I will join KCL as Lecturer in Molecular Biochemistry, and I will focus on computational investigations of RNA and protein structural ensembles.
#newPI 1/3

[Konstantin Roeder @KoRoeder]

@JnknsSJ Thank you!

[Konstantin Roeder @KoRoeder]

@__atreyee__ Danke!

[Konstantin Roeder @KoRoeder]

@NeelanjanaSeng1 Thank you - me too. There are some exciting ideas brewing in my head for a while now.

[Konstantin Roeder @KoRoeder]

@belgiantoffee Thank you - hope all is going well for you.

[Konstantin Roeder @KoRoeder]

@RNHeaton @maire_brace @paultgriffiths Thank you Richard. It was a great time and I have taken away a lot - and hopefully was able to have some impact too. I will definitely be back to visit.

[Konstantin Roeder @KoRoeder]

Bonus part: The paper is our work on Selective bond ruptures in Collagen. Here is the biorxiv version:
https://t.co/S1NmqCW3KT

[Konstantin Roeder @KoRoeder]

Last but not least, this wouldn't have happened without a lot of support. Thanks to @maire_brace, @paultgriffiths @RNHeaton David Wales and Samuela Pasquali, and everyone else during the last 7 years (no chance to fit everyone into a single tweet). 3/3

[Konstantin Roeder @KoRoeder]

@benerenne @graeter_mbm Really nice paper. We recently posted a preprint on bond ruptures in collagen (https://t.co/uJZQFNDKJr), and on first glance it looks like we agree on what we see. Which is great given that we used different simulation approaches.

[Konstantin Roeder @KoRoeder]

#NewPreprint #CompChem #xtb @ChemCambridge

[Konstantin Roeder @KoRoeder]

How do molecules in collagen fibres rupture when pulled? Turns out this happens selectively - read more in our new preprint here: https://t.co/S1NmqCEsmj

For a summary of what we found, read this thread. 1/

[Konstantin Roeder @KoRoeder]

These perturbation introduce weaknesses and lead to localisation of bond ruptures in the immediate proximity of the sequence alteration. Similarly, crosslinked strands also show localised ruptures around the linking site. 11/