Koschmann Lab

Pediatric Neuro-Oncology Research Lab striving to improve therapies for children with brain tumors through basic, transitional and clinical research.

[Mott Children's MD @MottDocs]

As part of the American Association for Cancer Research @AACR Report for 2025, Dr. @CarlKoschmann is featured in a new video highlighting Kaley Ihlenfeldt's journey with ONC201, the first FDA-approved therapy for recurrent DMG.

Learn more: https://t.co/U5Y0hjmx80.

[Koschmann Lab @KoschmannLab]

Incredible story about one of our patients who is a long term ONC201 survivor (now Modeyso!) -- released by @AACR today featuring our fearless leader @CarlKoschmann : https://t.co/Z33mkRkpOh

[Koschmann Lab @KoschmannLab]

We are happy to share that Dani (@DdlaNava) won 2nd prize for the TiP-ChIP grant via @activemotif! His project is analyzing epigenetic differences in pediatric diffuse midline glioma subtypes. We are looking forward to showing some interesting data soon! https://t.co/8lWRlxrW2R

[Koschmann Lab @KoschmannLab]

Today is 10/1! The incredible https://t.co/eWIX1gsWNc foundation is doing a 10-1 fundraising challenge. CUWJ is a generous supporter of our lab in honor of Jack Fineske. Please consider donating $10 and retweet/ask someone else to do the same! #DIPG #DMG https://t.co/thg034BoF0

[Koschmann Lab @KoschmannLab]

@BeckyPatrias She also passed along this nice message: "Please thank your lab for the work that you do. The political side anti-research voice is currently loud and negative. The vast majority of us are deeply grateful for the work that you basic scientists are doing." Thank you!

[Koschmann Lab @KoschmannLab]

Thank you to @BeckyPatrias for donating lunch and these incredible cupcakes for our lab meeting today! We all greatly appreciate it!

[Koschmann Lab @KoschmannLab]

Congrats Kallen! @CarlKoschmann s first PhD student is PhDONE! Not only that but Kallen's premiere first author thesis work is out today in @CancerCell in collaboration with @FilbinMariella @gojojohannes Amazing work! https://t.co/wOUS4OLrwI

[Carl Koschmann @CarlKoschmann]

HUGE Congratulations to @umichmedicine @KoschmannLab student Kallen Schwark defending his dissertation! Vistory dance here: https://t.co/o76ORegdTl

Look for his Cancer Cell paper coming out 3/13 on use of avapritinib in HGG in collab with @FilbinMariella and @gojojohannes labs

[Koschmann Lab @KoschmannLab]

HUGE congrats to the Brenner Lab! Anyone in this space knows how hard CLIA validation is, and this was a heroic effort. We're hard at work collaborating with this team to validate our best-in-class H3K27M ddPCR plasma test. Hoping to offer our test to patients later this year!

[Michigan Research @UMichResearch]

A @UMichMedicine lab has begun providing a first-of-its-kind new cancer test developed at U-M. MyHPVscore can detect human papilloma virus-related head and neck cancer by measuring fragments of tumor DNA in a patient’s bloodstream. https://t.co/SNsFbYsJPX

[Koschmann Lab @KoschmannLab]

Amazing! So happy to host Dani (@DdlaNava) who is a freshly graduated PhD rockstar from the @Alonso_Lab. Dani is using these funds to study biofluids (CSF/plasma) from patients on the IL13Ra2 CAR-T trial to identify patterns of response/resistance. Congrats Dani!

[ChadTough Defeat DIPG Foundation @chadtough]

Fellowship Grant: Daniel de la Nava of University of Michigan, mentored by Carl Koschmann.

🔬: @CarlKoschmann

[Koschmann Lab @KoschmannLab]

Super congrats to Sunny for this Fellowship award! Sunny is an outrageously talented MD/PhD student working on understanding ONC201 and associated resistance mechanisms. Really excited to put this money to good use!

[ChadTough Defeat DIPG Foundation @chadtough]

Fellowship Grant: Sunjong Ji of University of Michigan, mentored by Carl Koschmann.

🔬: @CarlKoschmann

[Koschmann Lab @KoschmannLab]

Our lab and @MottChildren Hospital continue to feel an amazing connection to Taylor and her community. You can follow the Taylor Lech Foundation on Instagram here: https://t.co/7gNjsaOV3T

[Koschmann Lab @KoschmannLab]

We are honored and humbled to receive continued support from the Taylor Lech Foundation. They are providing a critical $20,000 gift towards our efforts to improve H3K27M monitoring in blood and CSF from children and young adults with #DMG #DIPG

[Koschmann Lab @KoschmannLab]

CUWJ has been a supporter of our lab over the years and we are extremely thankful for all of the work that they do! Check out their website and consider donating here: https://t.co/QMHJSGjXQJ

[Koschmann Lab @KoschmannLab]

Sharing this amazing video from Brady Fineske of the Catching Up With Jack (CUWJ) foundation about their 10/1 donation drive. Please consider donating $10 and asking others to donate $1 today #DIPG #CUWJ https://t.co/doleaIado3

[Carl Koschmann @CarlKoschmann]

Another incredible @chadtough Run Tough 5K today. Amazing showing by @umichmedicine labs @vennetilab @KoschmannLab @johnprensner, Children’s CTSU, and @MottChildren employees and families - all for the most important cause- defeating DIPG.

[Koschmann Lab @KoschmannLab]

Honored to be included in this incredible group and excited to get to work with our collaborators @ShemaEfrat and @Guy_Ron. Thanks as always to the incredible @chadtough foundation!!! @UMRogelCancer @WeizmannScience @HebrewU

[ChadTough Defeat DIPG Foundation @chadtough]

GAME-CHANGER GRANT:
Dr. Carl Koschmann, University of Michigan

(Co-funded by the SoSo Strong Pediatric Brain Tumor Foundation)

[Carl Koschmann @CarlKoschmann]

@MottChildren @LuanneMarie @1daviswarren2 So honored to receive this support from #UCanCerVive on behalf of @KoschmannLab! Will get right to work on our shared commitment to improve treatments for children with brain tumors.

[Koschmann Lab @KoschmannLab]

Also, a well deserved shoutout to @chadtough @DefeatDIPG and the Carr family's impact on fundraising in the blog post #ChadTough 🧡🧡🧡

[Koschmann Lab @KoschmannLab]

Star PhD student @DanaDoesScience wrote this blog post describing the very complex way H3K27M mutations cause DIPG/DMGs in a way that's **accessible to non-experts**. Beautifully written and a great resource for patients, families, and non-experts alike! https://t.co/ZPMTEJI1lh

[Koschmann Lab @KoschmannLab]

@Wajd_MD @Alonso_Lab @Bando_Lab @castro2355_mg @MattDun17 @CHawkinsLab @FransonAndrea @vivekanandVNY @DrAmanda10 @johnprensner @Sabinmueller @NazarianLabs @RajenMody @RajuBrainLab @DanWahlMD @timphoenixUC And others! If you weren't tagged and would like to be, please comment/DM!

[Koschmann Lab @KoschmannLab]

Amazing! Kudos to everyone who organized (@chadtough @DefeatDIPG @JennyMosier @MarkWMosier @tamcarr21), attended , and contributed! This is truly a dream team #defeatDIPG

[Carl Koschmann @CarlKoschmann]

Announcing the release of the Roadmap for the Treatment of Pediatric DMG today in @Cancer_Cell which was led by @vennetilab and @KoschmannLab and put together by the brilliant team of researchers who came together for the @chadtough Defeat DIPG Workshop: https://t.co/EnSg493buD