Researchers at the @LieberInstitute learning, blogging & talking about #rstats, 📦s, @Bioconductor, #bioinformatics (our own opinions) Admin: @lcolladotor
Yoav @Y_Gilad kickstarts #BoG2026 at @cshlmeetings by asking us to be open minded and think beyond biology defined by means. To think about the dispersion / variance.
Aoxing @aoxing2 gave a great talk at #BoG2026 (even more considering it was last minute promoted to a talk!) on studying sex chromosome dosage thanks to available biobank data from rare but tolerated sex chromosome trisomies
Builds upon https://t.co/xL9UABCPfC
@cshlmeetings
Did you miss #BoG2026 or want to share your work or want to keep learning about great computational biology? Mike @mike_schatz invites us to #BDS26 later this year in November
Check https://t.co/ojI4bDNnuj for all the details!
@cshlmeetings
Brian Clearly’s work on « Fundamental errors in #RNAvelocity arising from the omission of cell growth » feels like a must read!!
Brian shouted out the co-authors in the second slide 👏🏽
#BoG2026@cshlmeetings
https://t.co/1yFnxfMjta
Boxiang @boxiangliu showcased #ISAAC for computing splicing QTLs #sQTLs using single cell data
They applied it to DLPFC 🧠 data from 722 donors
https://t.co/blZ5F3qbcY
#BoG2026@cshlmeetings
Megan D. Schertzer from @davidaknowles.’s lab invites us to use « perplexity » from Ecology to measure isoform diversity (or other molecular units).
Very thought provoking! 🤔
More at https://t.co/0LFzrhVljG
#BoG2026@cshlmeetings
Excited to announce that our #deconvolution benchmark has now been published in @GenomeBiology ! 📊
📄 https://t.co/A3oQERcuqF
Check out my blog post for a high level overview: https://t.co/WtyplwOi0e
A few months late, but here's our @libdrstats "End of year GitHub cleanup" 2024 activity guidelines
https://t.co/DSTIn8tStY
< 5 min
Thank you all #OpenSource developers who make #RStats and other software we depend on!
Check out this journal club presentation by Nick Eagles on:
> #ENACT: End-to-End Analysis of Visium High Definition (HD) Data
Nick also compared #ENACT against #bin2cell#VisiumHD@10xgenomics#PyStats
📼 https://t.co/dGfj10pY2g
🆕 journal club by Nick Eagles
"#Bin2cell reconstructs cells from high resolution #VisiumHD data" by Polański @RBartolom et al from @teichlab@YayonNadav labs
📜 https://t.co/AywC9MYEjm
🛝 https://t.co/eVcVdwrkID
📽️ https://t.co/nQ63fEW3tG
@10xGenomics
https://t.co/ih32nJpGGV
🆕 improved diagram for how #visiumStitched is able to help #BayesSpace, #PRECAST, & other array-based methods (col/row hex grid) find more neighboring spots when you have overlapping spots from different capture areas.
You already generated the 🤩 data, might as well use it!
One 💯 update is how Nick used the overlapping spots to calculate a matching rate in spatial cluster assignments
#BayesSpace with HVGs does better, whereas #PRECAST with #nnSVG SVGs does slightly better. Both improve when using #visiumStitched to increase the number of neighbors
I'm thrilled to share with you that #visiumStitched led by Nick Eagles has now been published
Our #RStats / @Bioconductor 📦provides a framework for stitching together multiple #Visium@10xgenomics capture areas together
https://t.co/T5SIJjrKY2
Today for @LIBDrstats I led a "Live exploration of latest #RStats news on Bluesky"
Bluesky intro: starter packs & feeds (aka algorithms)
+ @hadleywickham's curated feed, @Bioconductor news, and more
👀 https://t.co/6OCrX5GNhb
Manisha Barse presented with us for the first time!
She explained the metrics summary CSV files generated by SpaceRanger by @10xGenomics when processing #Visium spatially-resolved transcriptomics data
🛝 https://t.co/swgMAFKnIM
📽️ https://t.co/5F6YpBf7eW
Data viz with #RStats