Lisa-Marie Legault

PhD student. Working on epigenetic, embryonic development and FASD. Outdoor lover and chocolate addicted.

[Lisa-Marie Legault @LM_Legault]

@annesopepin @robert_ife @emboreports Congrats Anne-Sophie!!

[Serge McGraw @McGraw_Lab]

Thank you @CR_CHUSJ for showcasing our lab's work, led by @LM_Legault , on the impact of early embryonic alcohol exposure on the placenta. @CIHR_IRSC @FRQS1 #epigenetics

[Lisa-Marie Legault @LM_Legault]

Latest paper is now out! This one might be even more special as it is my last PhD paper. Thanks to all the co-authors & @McGraw_Lab thanks for everything. I was lucky to spend my years as a graduate student in such a stimulating environment, with an amazing team and involved PI.

[Serge McGraw @McGraw_Lab]

Paper alert! @LM_Legault et. al show that preimplantation alcohol exposure alters the #DNAmethylation and transcriptomic profiles in mouse placentas in a sex-specific manner, with DNA methylation being a robust predictive signature. https://t.co/dsZeXy23Nm @CR_CHUSJ #FASD

[Lisa-Marie Legault @LM_Legault]

Amazing project led by @eli__elder

Look at these figures 👌🏻

[Serge McGraw @McGraw_Lab]

What is the long-term impact of loss of sustained DNA methylation maintenance by DNMT1 for molecular and cellular integrity of mouse embryonic stem cells?

Thrilled to share the lab’s newest preprint https://t.co/jVkiCsfMwr
Amazing effort from @eli__elder and team!
🧵1/11

[Lisa-Marie Legault @LM_Legault]

@arianelismer Congrats Ariane!!

[Lisa-Marie Legault @LM_Legault]

@amy_inkster @McGraw_Lab @BiologySexDiff @CR_CHUSJ @UMontreal @NSERC_CRSNG Thanks Amy!

[Serge McGraw @McGraw_Lab]

Our newest publication in @BiologySexDiff , highlighting the importance of including sex-based analyses in epigenetic and transcriptional studies of the mouse placenta. Congrats @LM_Legault !! @CR_CHUSJ @UMontreal @NSERC_CRSNG https://t.co/aOCmzjs51c

[Lisa-Marie Legault @LM_Legault]

@annesopepin @McGraw_Lab @BiologySexDiff @CR_CHUSJ @UMontreal @NSERC_CRSNG Thanks!!

[Lisa-Marie Legault @LM_Legault]

@KimminsSarah @McGraw_Lab @CR_CHUSJ @UMontreal Thanks Sarah!!

[Lisa-Marie Legault @LM_Legault]

@McGraw_Lab @CR_CHUSJ @UMontreal Merci pour tout Serge (@McGraw_Lab) !! Was lucky to spend the last years in your lab and learn so much in a great atmosphere!!

[Lisa-Marie Legault @LM_Legault]

@_alexlangford @McGraw_Lab @CR_CHUSJ @UMontreal Merci!!

[Lisa-Marie Legault @LM_Legault]

@SGPlacenta @McGraw_Lab @CR_CHUSJ @UMontreal Merci Sylvie!!

[Lisa-Marie Legault @LM_Legault]

@DrTonyKwan @McGraw_Lab @CR_CHUSJ @UMontreal Thanks Tony!

[Lisa-Marie Legault @LM_Legault]

@KC0nn0r @McGraw_Lab @CR_CHUSJ @UMontreal Thanks Kristin!!

[Canadian Epigenetics @CEEHRC]

And that's a wrap on #CanEpi23! Thank you to everyone who attended and all of the sponsors for their continued support of our meeting. We've enjoyed seeing all of the amazing science and wonderful interactions that have taken place over the last 3 days.

See you all in 2024!

[Lisa-Marie Legault @LM_Legault]

@SGPlacenta @McGraw_Lab @CEEHRC @CR_CHUSJ Thanks Sylvie!

[Serge McGraw @McGraw_Lab]

Explore our latest @Preprints_org review aiming to highlight O-GlcNAcylation's central role as an epigenetic mark, focusing on histone modifications. Collaboration with Thomas Dupas (new postdoc in our lab) and Prof. Benjamin Lauzier (@NantesUniv France ) https://t.co/IrIaYbiSnv

[Serge McGraw @McGraw_Lab]

Our News and Views ―Inheritance of epigenetic DNA marks studied in new mouse model― of the Takahashi et al. Cell 2023 paper on the Transgenerational inheritance of acquired epigenetic signatures at CpG islands in mice. Fun collaboration with @KimminsSarah https://t.co/YGtUjhn5Bi

[Lisa-Marie Legault @LM_Legault]

@KimminsSarah Congrats Anne-Sophie!! 🍾

[Serge McGraw @McGraw_Lab]

Happy to share our study in @FASEBorg ! Using a mouse model of pre-implantation alcohol exposure, we show that a maternal enriched diet for methyl-donor mitigates the negative impacts of alcohol exposure. #FASD https://t.co/GaQEpHQtH5