Craig Repro Tox Lab

Our dream? A world where all women are healthy and have healthy babies! How are we helping? We investigate how chemical exposures affect female fertility.

[Craig Repro Tox Lab @LabCraig]

The Southwest Environmental Health Sciences Center recently published a plain language Research Summary about one of our papers. Check it out here: https://t.co/2Cv6NMmxIP
#Phthalates #EnvironmentalHealth #EndocrineDisruption #WomensHealth

[Craig Repro Tox Lab @LabCraig]

Our latest publication has been featured as a Tox Spotlight Article by the journal of the Society of Toxicology! #Phthalates #EnvironmentalHealth #EndocrineDisruption

[Toxicological Sciences @ToxSci]

Di-n-butyl phthalate tampers with the ovarian IGF1, providing molecular insight into how #Phthalates could influence the ovarian reserve. #ToxSpotlight #FreeToRead @zrcraig @LabCraig https://t.co/ctSTnjVxaO

[Craig Repro Tox Lab @LabCraig]

We demonstrate low follicle counts, reduced activated IGF1 receptor signaling in the ovary after human-relevant exposure to di-n-butyl phthalate in young adult mice

https://t.co/s1NKA9Oabs

[Craig Repro Tox Lab @LabCraig]

Kara Miller presenting her graduate work profiling fatty acids in ovarian follicles exposed in vivo to a three-phthalate mixture #SSR2023

[Craig Repro Tox Lab @LabCraig]

Doctoral Candidate, Kara Miller, and Principal Investigator, Zelieann Craig, representing the Craig Lab at the Annual Meeting of The Society for the Study of Reproduction in Ottawa. #SSR2023

[Craig Repro Tox Lab @LabCraig]

Craig Lab Potluck Monday! ❤️

[Craig Repro Tox Lab @LabCraig]

Looking for papers about parabens and ovarian follicle exposures? Check out this report from Gal et al.

https://t.co/3qobGFpXb6

[Craig Repro Tox Lab @LabCraig]

#ThrowbackThursday

2020: we published our first Data in Brief publication providing raw data on uterine DNA methyltransferase activity in mice fed control and dibutyl phthalate to the scientific community.

https://t.co/88WqJ0WfUi

[Craig Repro Tox Lab @LabCraig]

#ThrowbackThursday

2017: effects of direct exposure to dibutyl phthalate, monobutyl phthalate, acetyl tributyl citrate on growth, cytotoxicity, cell death, and gene expression in mouse ovarian follicles.

https://t.co/1J8zQv1rRB

[Tech Launch Arizona @UAZTechLaunch]

Exciting news: #WorldIPDay is in 2 days! Sadhana Ravishankar, TLA's Inventor of the Year & founder of PhytoCentric Solutions, is an inspiring woman in STEM who developed a non-toxic, natural sanitizer safe for consumers & the environment: https://t.co/r1x2yUo8Uj #WomenInSTEM

[Tech Launch Arizona @UAZTechLaunch]

Excited to celebrate #WorldIPDay in 6 days & recognize innovators like Jennifer Barton, Director of @UAZBIO5 🔬🧫 Her work in biomedical imaging & optics led to advancements in cancer diagnosis & treatment: https://t.co/jVmrwQRsnG

[Craig Repro Tox Lab @LabCraig]

#ThrowbackThursday

Back in 2016, we reported that the phthalate substitute, acetyl tributyl citrate (ATBC), increased spleen weight and decreased small ovarian follicle numbers in mice treated orally with a low dose never tested before.

https://t.co/HPc3bxzwmw

[Craig Repro Tox Lab @LabCraig]

#ThrowbackThursdays
That one time we measured the distribution of mono butyl phthalate to the ovary and liver in adult female mice fed with dibutyl phthalate and observed evidence of adaption during single vs repeated dosing schemes.

https://t.co/7kK7JO4f7E

[Craig Repro Tox Lab @LabCraig]

#Throwback to when we found that oral exposure to a phthalate lowers ovarian expression of BRCA1 mRNA and protein in mice.

Environmentally relevant exposure to dibutyl phthalate disrupts DNA damage repair gene expression in the mouse ovary

https://t.co/1XbyZXr44l

[Craig Repro Tox Lab @LabCraig]

Our first preprint submission is available! Let us know what you think!

https://t.co/kH9ItdbA5z

[Craig Repro Tox Lab @LabCraig]

Do you remember when you joined Twitter? I do! #MyTwitterAnniversary

[Toxicological Sciences @ToxSci]

#Phthalate systemic distribution to and biological effects in liver and ovaries. @zrcraig @LabCraig https://t.co/AK8W3VGg8H

[Craig Repro Tox Lab @LabCraig]

Check out our latest publication in Toxicological Sciences!
https://t.co/3K3FyVojfA

[Craig Repro Tox Lab @LabCraig]

So proud of Dr. Jauregui!! 🎉🎉

[BIO5 Institute @UAZBIO5]

#MeetOurPostdocs: Dr. Estela Jauregui is a @UArizona ACBS #postdoc fellow in the lab of @UAZBIO5 member Dr. @zrcraig. Dr. Jauregui is studying the sex differences in reproductive toxicity caused by phthalates, an ingredient common in many personal care products. #DISCOVERBIO5

[Craig Repro Tox Lab @LabCraig]

Our postdoc Dr. Estela Jauregui was awarded a BIO5 Institute Postdoctoral Fellowship Award to study sex differences in reproductive toxicity by phthalates! Way to go, Estela!!

[BIO5 Institute @UAZBIO5]

Congratulations to our most recent Postdoctoral Fellowship Awardees! Chosen from a competitive pool of @UArizona #postdocs, all 8 are collaborating with faculty @UAZBIO5, working in fields from #plant science to #cancer. Read more and #DISCOVERBIO5.
https://t.co/NJd8GWURLK