Klymchenko Lab

Nanochemistry and Bioimaging Team UMR7021 @LBP_Illkirch @unistra @aklymchenko

Fluorescent nanoparticles & probes for nanomedecine & bioimaging. ERC #BrightSens

[Andrey Klymchenko 🇺🇦 @aklymchenko]

Trilled that our work on reaction-based nanosensor of neurotransmitters is on the cover @J_A_C_S ! Lock-and-key molecular recognition of dopamine inside a lipid nanoreactor triggers an irreversible reaction, leading to fluorescence turn-on of the nanosensor. @ERC_Research @CNRS

[Andrey Klymchenko 🇺🇦 @aklymchenko]

We thank @CNRS for highlighting our work on artificial receptors for detection of neurotransmitters that just came in @J_A_C_S
https://t.co/3towndJ2P7

@ERC_Research @CNRS @unistra

[Andrey Klymchenko 🇺🇦 @aklymchenko]

Happy to share our paper in @J_A_C_S on a concept of reaction-based sensing of neurotransmitters driven by a molecular recognition in a lipid nanoreactor. Congrats and thanks to co-authors! @ERC_Research, @unistra @CNRS. https://t.co/mtV2bvOz8c

[Andrey Klymchenko 🇺🇦 @aklymchenko]

Just published: we report fluorescent polymeric nanofibers for multiplexed sensing of pH and oxygen & their applications for wound healing. @Wiley_Chemistry Congrats to co-authors: Remi Pelletier & @anil89. @ConectusAlsace, @ERC_Research, @CNRS @unistra
https://t.co/pgqKFaApjr

[Andrey Klymchenko 🇺🇦 @aklymchenko]

New BioRxiv preprint: we introduced a tool kit of fluorescent probes for organelle sensing based on popular solvatochromic dye Prodan. Great collab. with @Sciezgin team @karolinskainst. Congrats & thanks to co-authors! @CNRS @unistra @AgenceRecherche
https://t.co/zTN0itgngW

[Andrey Klymchenko 🇺🇦 @aklymchenko]

Just out in @nanoscale_rsc: we developed a plug-and-play "green" functionalization of nanoemulsions with antibodies for specific cancer cell targeting. Great collab. with @GoetzJacky team! Thanks to all co-authors! @AgenceRecherche @CNRS_Alsace @unistra
https://t.co/j28qL0LAop

[Andrey Klymchenko 🇺🇦 @aklymchenko]

Just out @nanoscale_rsc: we found cooperative effects in DNA-functionalized polymeric nanoparticles, important for biosensing & diagnostics. Congrats & thanks to Paraskevi Gaki & startup BrightSens Diagnostics. @unistra, @CNRS_Alsace, @Bpifrance, #iLab
https://t.co/Ttie63tzcK

[Andrey Klymchenko 🇺🇦 @aklymchenko]

Our review on light-harvesting nanomaterials for energy transfer & biosensing is out @Wiley_Chemistry Adv Mater! We analyzed literature on optical materials mimicking nature – chlorophyll in plants. Thanks & congrats to co-authors: @SekharDeep & P. Didier! https://t.co/S9aJEVkyBx

[Andrey Klymchenko 🇺🇦 @aklymchenko]

The social program of @FASEBorg conference on #Optical #Probes in Phoenix, Arizona, was rich, including bull riding, tasty local food, sessions in the swimming pool and discovery of scorpions in the garden next to us.
Thanks to local organizers: Evan Miller, Luke Lavis & others!

[Andrey Klymchenko 🇺🇦 @aklymchenko]

What a great experience to participate in the @FASEBorg meeting on #Optical #Probes in Phoenix, Arizona! Big thanks to the organizers for the invitation and organization of this great event: Evan Miller, Luke Lavis, Marina Kuimova and others.

[Andrey Klymchenko 🇺🇦 @aklymchenko]

Great news: I received ERC Advanced grant #ERCAdG @ERC_Research CaptuRel! It aims at intelligent nanomaterials undergoing bioinspired cycle of capture and photorelease of bioactive molecules for sensing and controlling (bio)chemical gradients. Thanks to my Team, @CNRS @unistra !

[Andrey Klymchenko 🇺🇦 @aklymchenko]

Congratulations to Tanushree Gupta on the brilliant PhD defense on peptide-polymer nanoparticles! It has been a long journey having Roller Coaster parts and happy end. Thank you for your hard work! Many thanks to the jury and our collaborators. @AgenceRecherche @unistra @CNRS

[Andrey Klymchenko 🇺🇦 @aklymchenko]

The final destination in Japan was Sendai, to participate in 29th FJS chemistry symposium at @TohokuUniPR, and give a lecture on our research. Amazing atmosphere with many interesting discussions and top-quality lectures. Big thanks to the organizers!

[仁子 陽輔（Yosuke Niko） @NikoYosuke]

Finally got to see my amazing former boss, @aklymchenko , here in Japan!
This time, it looked like we got caught in the rain—digitally.
Next time, I hope to welcome you to one of the sunniest places in Japan, Kochi!

[Andrey Klymchenko 🇺🇦 @aklymchenko]

The next stop in Japan was @sciencetokyo_en, team of K. Genichi @Alc_Rimbaud, to discuss our research. Then, I had an amazing time in Tokyo with my friend @NikoYosuke and his wife Maki, discovering the beautiful city. I will keep many unforgettable memories, thank you! Arigato!

[Shuhei Furukawa Group @FurukawaG_Kyoto]

So happy to welcome you @aklymchenko to Kyoto!! We realized we had not changed much since we met. Note to our old Leuven friends, Andrey talks as much as 20 years ago :)

[Andrey Klymchenko 🇺🇦 @aklymchenko]

My first time visit to Japan started with visit of my good old friend @FurukawaG_Kyoto, Prof. at the @iCeMS_KU_INTL. Unbelievable experience to meet brilliant colleagues, present and discuss our research and try authentic food and drinks from Kyoto! Thank you so much, Shuhei!

[Andrey Klymchenko 🇺🇦 @aklymchenko]

New preprint: we introduce peptide-functionalized fluorescent polymeric nanoparticles with stealth properties due to short polysarcosine peptides for targeting proteins on cell surface. Congrats to co-authors! @CNRS_Alsace @unistra @AgenceRecherche
https://t.co/H1I60Ejs1e

[Andrey Klymchenko 🇺🇦 @aklymchenko]

We revisited our #MemBright toolbox and report anionic cyanine membrane probes with improved properties that enable in vivo imaging of neurons in mice brain. Congrats to @DanylchukDmytro, @IgorKhalins & co-authors! Just out @an_chem:
https://t.co/gP5IrQuRFn
@CNRS_Alsace

[Andrey Klymchenko 🇺🇦 @aklymchenko]

New preprint alert: we found cooperative effects in DNA-functionalized polymeric nanoparticles, important for biosensing and diagnostics applications. Congrats and thanks to co-author Paraskevi Gaki. @unistra @CNRS_Alsace, @Bpifrance, #BrightSens #iLab
https://t.co/XC40nsRVoU