Josef Lazar

Seeing new things by using fluorescent proteins and interesting microscopes

[Josef Lazar @LazarLab]

And for the insulin receptor enthusiasts out there: we see, among other things, that inhibiting the intracellular kinase has an effect on the extracellular ectodomain. So, doing experiments just on the ectodomain (ignoring the kinase) is a risky business!😬

[Josef Lazar @LazarLab]

Our paper on a FLIP biosensor that allows microscopy imaging of activity of the insulin receptor is out👍 Thank you to everyone involved, and congratulations to Alina!

https://t.co/593YdOTbd6

[Josef Lazar @LazarLab]

Looking forward to presenting (on Oct 15) at the 120 Seconds BrnoRegion Microscopy event (https://t.co/4GZWt7O0YO)🔬 and at the Inst. of Scientific Instruments in Brno! Come see some cool images (and maybe even two Josef Lazars together!🤔😇) and talk to me aftewards!🍷🍻

[Josef Lazar @LazarLab]

A beautiful tribute to Pavel Jungwirth, by some of those who knew him the best as a scientist:
https://t.co/lr8bO949a5

[Josef Lazar @LazarLab]

We are collaborating with Innovative Bioimaging (@InnovativeBioi1) on development of an ultrafast confocal microscope for linear dichroism (LD) imaging... It seems to be coming together!😎

[InnovativeBioimaging @InnovativeBioi1]

Testing our new ultrafast confocal microscope… Not bad!🤔 In fact, pretty amazing!😎😊

[CzechBiophysics @CzechBiophysics]

In Pavel's honor, please consider contributing to one of the organizations chosen by his family:
https://t.co/M0GZQ0QqBr

[CzechBiophysics @CzechBiophysics]

As has now been publicly announced, Pavel Jungwirth, a star Czech physical chemist and an overall excellent person has passed away...🖤 He will be very much missed by the scientific community, his many friends, but above all, his family. What a sad day...🥹

[Josef Lazar @LazarLab]

@CzechBiophysics Always so full of life and ideas... An ERC grant in progress... An excellent person in so many ways... It's hard to believe. Sad news, indeed!🖤🥹

[Josef Lazar @LazarLab]

@ArmadaCR Ahoj Jardo - slyšel jsem tě dnes letět! Úžasný, kam jsi to dotáhl! Ať se ti dál daří! Zdravim, Pepa Lazar

[Josef Lazar @LazarLab]

We have now been granted a US patent on our FLIP biosensors, co-developed and commercialized by Innovative Bioimaging (@InnovativeBioi1)🤩

[Josef Lazar @LazarLab]

I had the honor to present a talk (in the big room!🤩😱) about our FLIP biosensors and an ultrafast confocal microscope (@InnovativeBioi1)!

[Josef Lazar @LazarLab]

Just got back from #ELMI2026 in Coimbra, Portugal - an excellent meeting for optical microscopists! Coimbra is a beautiful place🏰with small beers 🍻🙂. A Czech trace: one of the local brews is named Jan Kubiš!🍺🇨🇿

[Josef Lazar @LazarLab]

@JohannesPilic My subjective perception of scientific success... A little hard to measure accurately🙂 My postdoctoral lab running out of money before I published anything was hard

[Josef Lazar @LazarLab]

Unrelated: last week I gave a seminar for the students of the Science program of Charles University (https://t.co/xSoFj9ioeq). Seems like an excellent program and a lovely group of students!👍😍 I hope they enjoyed it as much as I did!

[Josef Lazar @LazarLab]

I took my hand (specifically, my hurting middle finger) to the doctor today... Here is the result😇. They made me do it😂. Less fun: if you look closely, you will see that the end of the bone is crushed🙄

[Josef Lazar @LazarLab]

Got my hand pinched by a door a week ago... Ouch! 😰 One of my fingers still hurts, but Petro has now at least made it look better... At least in Photoshop🙂

[Josef Lazar @LazarLab]

The actual video can be watched here... We are on at time 6:29
https://t.co/P0o3H9Hh35

[Josef Lazar @LazarLab]

Almost famous 😇

[Josef Lazar @LazarLab]

Our HEK293 cells celebrate Valentine's day! ♥️🙂

[Josef Lazar @LazarLab]

Check out how this translocation-based biosensor develops linear dichroism (when the orientational freedom of the fluorescent protein becomes restricted)! 😎 Imaged with our new, super-fast confocal LD microscope🔬⚡️, now available from https://t.co/rvRYJcEXny