Leah Briscoe

Data Scientist

[Nandita Garud @nanditagarud]

I have received tenure!! I am grateful to my lab for making science a joyous endeavor. @UCLAEEB has been an unequivocally supportive dept and I am grateful to my colleagues, who have been major advocates of my career. Thank you to my mentors, friends, colleagues, and lab members!

[Leah Briscoe @LeahBriscoe]

Just as we humans have a critical learning period in our earlier years, new work is showing that there is a critical learning period for deep network models. Check out this interesting work by my colleague Michael.

[Michael Kleinman @MichaelKleinman]

Excited to share our @iclr_2024 spotlight paper. Our work shows that critical learning periods exist in a minimal analytically tractable model of artificial deep networks (deep linear networks) trained with SGD.

Paper: https://t.co/Qb6TyfiWEZ
Work w/ A. Achille & S. Soatto

[Leah Briscoe @LeahBriscoe]

Impressive work by my friend Linh Le: a noteworthy advancement in benchmarking CO activation in Iron-Sulfur clusters — very important in understanding metabolic pathways and biological nitrogen fixation !

[GⱯGⱯIST OHLⱯLⱯ @gagaistohlala]

Our latest work in @J_A_C_S discusses a WFeS cluster with bridging carbyne and highly activated terminal CO (vCO < 1800 cm-1). Computation identifies an unusual intermediate spin state at Fe promoted by the carbyne. Thanks to everyone for the contribution. https://t.co/htVF3FmkjH

[Leah Briscoe @LeahBriscoe]

@gagaistohlala Was this the quiz you gave in class ?

[Leah Briscoe @LeahBriscoe]

@HaVu_science @UCLA Thank you!

[Leah Briscoe @LeahBriscoe]

@jjminich @nanditagarud @halperineran These are good questions! The ideal input would be high coverage shotgun metagenomic data (ideally coverage > 10). Long read data will likely improve the performance of the method, as the SNP calling should be better due to higher overlap of reads! I do not foresee issues!

[Leah Briscoe @LeahBriscoe]

Excited to share that our paper on microbial source tracking using single nucleotide variants is officially out at Genome Biology! Thank you @nanditagarud and @halperineran. Check out the interesting patterns we find in the ocean microbiome and the NICU at https://t.co/UviYLTtGf0

[Leah Briscoe @LeahBriscoe]

@gagaistohlala next year, my friend!

[Leah Briscoe @LeahBriscoe]

@gagaistohlala Agreed! Album of the year should have been Beyoncé

[Leah Briscoe @LeahBriscoe]

@ruthie_johnson Amazing data collection methods

[Nandita Garud @nanditagarud]

We are delighted to share that our paper on Enrichment of Hard Sweeps on the X Chromosome in Drosophila melanogaster is now out in MBE! This work is with the very talented first author and PhD student, Mariana Harris @MarianaHarr. https://t.co/OYgK1IVLVJ (1/n)

[Leah Briscoe @LeahBriscoe]

@yi_ding_ @ruthie_johnson He does !

[Ruthie Johnson @ruthie_johnson]

Our work cataloging the genetic ancestry map of UCLA patients is now published in @GenomeMedicine! This is the result of a multi-year project that could not have been done without the generosity of the patients at @UCLAHealth. A thread on our key findings:
https://t.co/yZzw36dzdF

[Leah Briscoe @LeahBriscoe]

@ruthie_johnson 🥳

[Leah Briscoe @LeahBriscoe]

@gagaistohlala I found video that not too long ago and it’s crazy to think it even exists

[Jazlyn Mooney, PhD @Jazlyn_Mooney]

Finally seeing pictures from our fantastic @qbio_usc symposium honoring Michael Waterman, aka Watermania. I already can't wait for the next one. If you are a grad student or postdoc heading to PEQG and want to join my group and a great department please reach out!

[Leah Briscoe @LeahBriscoe]

@gagaistohlala Thanks Linh!

[Leah Briscoe @LeahBriscoe]

In sum, source tracking with SNVs can offer new insights into microbiome transmission and colonization sources that species cannot. We welcome your comments! (8/8)

[Leah Briscoe @LeahBriscoe]

We are thrilled to share our preprint paper on microbial source tracking using single nucleotide variants @halperineran @nanditagarud https://t.co/BFfTr07K8Y (1/x)

[Leah Briscoe @LeahBriscoe]

We additionally observe evidence of endemism of microbiome communities in the Mediterranean Ocean. (7/x)

[Leah Briscoe @LeahBriscoe]

Additionally, with SNV source tracking, we track migration of microbes across oceanic regions, including across the Suez and Panama canals, and observe a distance-decay relationship in the source contribution, which we do not observe with species source tracking. (6/x)