Leandro Feo

Colorectal surgeon in Boca Raton, FL. colorectal surgical oncology. Loves football (soccer) tweets=mine

[DCRjournal @DCRjournal]

#DCRJournal visual abstract recap | Rectal Cancer Survival for Residual Carcinoma In Situ Versus Pathologic Complete Response After Neoadjuvant Therapy: https://t.co/E2LB7qJHzS

@SeanLangenfeld @Schadi_CRS @slsteinmd1 @MarkSoliman @rahila_essani @JohnRTMonsonMD @SoniaRamMD

[Steven D Wexner MD, PhD @SWexner]

Outcomes of Organ‐Preserving Local Excision Compared to Radical Resection in Stage I Early‐Onset Rectal Cancer: A Propensity‐Score SEER‐Based Analysis https://t.co/Szmg7ZofSU new publication by @dr_samehhany81 @AWignakumar @DouradoJMD

[Sameh Emile, MD, FACS @dr_samehhany81]

New pub: Fragility Index analysis for robustness of evidence in Randomized Controlled Trials in @NCCN guidelines for rectal cancer
@CleveClinicFL @SWexner @nirhoresh @DouradoJMD @PRogers125 @ZGaroufalia @RachellGefen @PaAeschbacher @salama_ebram https://t.co/z8vDtGr0Xu

[DCRjournal @DCRjournal]

The Microbiome in Colorectal Anastomotic Healing: The Cart or the Horse? This #DCRJournal Editorial explains: https://t.co/TKY6SinTIX

@SeanLangenfeld @Neil_J_Smart @TAMISYoda @Schadi_CRS @Doc_Brown44 @drjamestaylor @KarasJoshua @MaloneyNell @Averywalker21

[Sameh Emile, MD, FACS @dr_samehhany81]

New pub: Role of Neoadjuvant Chemotherapy Before Simultaneous Resection of Colon Cancer and Liver Metastases: A Propensity-Score Matched Analysis
@CleveClinicFL @SWexner @ZGaroufalia @RachellGefen @DouradoJMD
https://t.co/WYfkHg4RBq

[Wolfgang Gaertner @GaertnerWB]

LARS @ASCRS_1 clinical practice guidelines under the direction of @BoutrosMarylise coming soon!

[Steven D Wexner MD, PhD @SWexner]

Intraoperative indocyanine green fluorescence angiography in colorectal surgery to prevent anastomotic leakage: A single‐blind phase III multicentre randomized controlled trial (FLUOCOL‐01/FRENCH 21/GRECCAR 19 intergroup trial) https://t.co/jAGy2mpBOa @ColorectalDis 🇫🇷

[Steven D Wexner MD, PhD @SWexner]

A pilot study of gut mucosal and faecal microbiota in rectal cancer: associations with histological response and adverse events following preoperative chemoradiotherapy https://t.co/1AKqJa3Hdi @ColorectalDis open access

[Emil Lou, MD, PhD, FACP, FASCO @cancerassassin1]

Gene-editing therapy shows early success in fighting advanced gastrointestinal cancers https://t.co/oAEgilP6Au via @medical_xpress

[DCRjournal @DCRjournal]

#DCRJournal Real World Questions

What do you think? Reply & let's discuss!

@SoniaRamMD @justinmaykel @changtangMD @luciacolorectal @deanlute @juliomayol @drjamestaylor @KarasJoshua @MaloneyNell @Averywalker21

[Leandro Feo @LeandroJFeo]

@DCRjournal @SoniaRamMD @justinmaykel @changtangMD @luciacolorectal @deanlute @juliomayol @drjamestaylor @KarasJoshua @MaloneyNell @Averywalker21 1.- Definitely will be and already in progress incorporated in the daily operations at the office , improving the work flow , and efficiency .
2.- ML predicting models utilizing for example digital twins to anticipate outcomes , based on patient profile .
3.- Iot data analysis

[Leonardo Bustamante-Lopez, M.D. Ph.D @Leo708]

Colorectal Cancer Prevention Webinar!

ISUCRS live, Saturday April 19th, at 9:00 am ET.

Webinar is free. Registration is required.

Site for registration:

https://t.co/jYoMty4zaC

or https://t.co/Bo9v2bukRC

#Colorectalcancer
#Colorectalprevention
#Colorectalresearch

[Steven D Wexner MD, PhD @SWexner]

Network Meta-analysis of RTCs for Efficacy of Neoadjuvant Treatment in... https://t.co/jhx3ws3QA4 @ejsotweets from @CleveClinicFL @dr_samehhany81 @nirhoresh @RachellGefen @ZGaroufalia @PaAeschbacher @salama_ebram @PRogers125

[Leandro Feo @LeandroJFeo]

@LatinoSurgery @isa_miret Excelente , Felicidades . Powerhouse

[Steven D Wexner MD, PhD @SWexner]

Diagnostic performance of procalcitonin for detecting anastomotic leak in older adults with colorectal cancer: A delayed type cross-sectional study - @SurgJournal https://t.co/1mEqmDiTt4

[Steven D Wexner MD, PhD @SWexner]

The use of preoperative enteral immunonutrition in patients undergoing elective colorectal cancer surgery: A systematic review and meta‐analysis @ColorectalDis open access https://t.co/cuKp9UVWNW

[Sean Langenfeld @SeanLangenfeld]

Interesting new Finnish RCT in @JAMASurgery evaluating ICG's impact on anastomotic leak in colon surgery. The results won't make you switch camps, regardless of which one you're in, but they're important:

-No difference in AL rates, reoperations, or overall complications between the ICG and control groups.

-Trend toward decreased AL in left-sided anastomoses for ICG (interpret with caution)

-No patients received oral abx, and the group was mixed on no prep vs mechanical vs enemas.

-LARs excluded, which would have presumably been at a higher risk of compromised perfusion and leak, and were the focus of previous studies.

-Anastomotic configurations varied, with a lot of isoperistaltic linear right-sided anastomoses, and 20% of left-sided anastomoses either linear or handsewn (vs circular stapled).

-More than 50% of surgeons in their first 10 years of practice, and about 30% with less than 50 previous lap colon cases.

-Overall leak rates of 6-10%, which is probably higher than what a lot of us quote patients.

Take home point (IMHO): perfusion is but one of many contributors to anastomotic leak, and ICG may make you feel better, but it won't bring your leak rate below 5%.

https://t.co/X2KmLaTP6P

[Steven D Wexner MD, PhD @SWexner]

Transition to lateral lymph node dissection in rectal cancer: Forty-five years of outcomes data https://t.co/34aaHjDVyS @SurgJournal from 🇯🇵 “The impact of lateral lymph node dissection on rectal cancer treatment may not have changed in 45 years, given the lack of difference in relapse-free survival.”

[Sean Langenfeld @SeanLangenfeld]

Excellent @DCRjournal study from @JonVogel7 and team looking at 545 US patients with rectal cancer undergoing watch-and-wait after a cCR.

Only 18 (3%) were MMR deficient.

As much as we all hope to find dMMR rectal cancers to treat with immunotherapy, they're very uncommon.

https://t.co/VEaUcf8LoD

[LatinoSurgSociety @LatinoSurgery]

LSS and @SocietyofBAS 🔥🙌🏽 at #EAST2025