The three-part New Drugs on the Horizon Series at the AACR Annual Meeting 2025 wrapped up this morning. A total of 12 first-time disclosures were presented. #AACR25
Molecule One-Pager: ARV-471 (vepdegestrant)
This molecule one-pager includes links to key presentations, publications, patents, preclinical and clinical PK data summaries, and more.
One-pager link: https://t.co/W4Gsc8NAZC
BMS-986365: A Next-Generation Oral AR Heterobifunctional Degrader for Drug-Resistant Prostate Cancer
This full case study details how BMS-986365 was engineered to have low intrinsic agonism and exert direct antagonism of WT AR and more!
Full Article: https://t.co/z1pJwj81yy
Événement : journée thématique de la #chimie accélérée et digitalisée en R&D le 19 septembre prochain à Paris Saclay! Au programme Laurence Grimaud (@ENS_ParisSaclay ) Pascal Mieville (@EPFL), Raphaël Steimbach (@Servier), Florian Médina (@JNJNews) et bien d’autres !
Very nice to be back in Bristol for the CDT Summer Conference. A lot of great science presented by very talented PhD students ! Congratulations to @JonathanClayden, @VarinderAggar11 and @BCS_CDT
I keep being amazed by the work from @Rev_Medicine Here is a example from their last patent. This work is again pushing medicinal chemistry out of out comfort zone. 6 chiral centers, 1 atropisomer , a spiro and an aziridine ! Congratulations to @Les_Burnett and all the Team!
There is still time to register for the Thematic meeting from @SCT_asso: Targeted Protein Degradation Gentilly @SanofiFR (Paris) with a fantastic program. You can click under the following link https://t.co/K4JhRcj8rk
There is still time to register for the Thematic meeting from @SCT_asso: Targeted Protein Degradation Gentilly @SanofiFR (Paris) with a fantastic program. You can click under the following link https://t.co/K4JhRcj8rk
Come and join us, what are you waiting for?! We have a fully funded PhD position @UniBonn on Sb- and Bi-luminescent compounds🧪. The deadline is April 24, interested candidate should send the application (cover letter and CV) to [email protected]
Come and join us, what are you waiting for?! We have a fully funded PhD position @UniBonn on Sb- and Bi-luminescent compounds🧪. The deadline is April 24, interested candidate should send the application (cover letter and CV) to [email protected]
🔥🔥“TPD one-day Thematic meeting” in Paris (SANOFI) May 30th 2024 @SCT_asso : register open https://t.co/HlYneqPRGD
@DanNomura
Dr. M. Schroeder
@fmorreale_ester
Prof. N. Thomä
@iDikic2
Dr. M. Koegl
Dr. S. Jegham
Dr. K. McAulay
Prof. A.-S. Voisin-Chiret
Molecules of the Month – Feb. 2024
Actelion revealed the discovery story of nivasorexant, a selective orexin-1 receptor antagonist, which completed a Ph. II clinical trial in binge-eating disorder.
Check out our other top molecules from Feb.!
Article | https://t.co/XKdteK7gqq
We have an open position for a postdoc in our Medicinal Chemistry & Drug Design department @merckgroup: If you are equally excited about chemistry automation and about applying synthetic chemistry to answer biological questions, check out this highly attractive opportunity!