Liam Akroa

Vitalist trying to outgrow the Decay

[Liam Akroa @Liam_Akroa]

@MartinBJensen I wonder why siRNA doesn't degrade in the lysosome? Are there synthetic bases and backbone modifications to prevent nuclease binging? And if nucleases aren't binding, how are nuclear import proteins binding?

Seems like an important lever for longer lasting doses.

[Liam Akroa @Liam_Akroa]

@LoganTCollins Do you think we can define suffering in the same way for eusocial organisms?

The individual pain response exists, but there might also be a pheremone-based response in other individuals.

[Liam Akroa @Liam_Akroa]

Wonderful to see New Hampshire accelerate access to treatments!

[Granite Bio Innovation @GraniteBio]

The New Hampshire House has again voted in favor of HB 1734 and HB 1735 - two bills to make New Hampshire a hub for experimental therapies.

SB 504 was amended to include both bills and then passed the House 197-145, this time picking up several Democrats.

[Liam Akroa @Liam_Akroa]

@emilylmullin Extremely underinvested area compared with in vitro organ engineering. Excited to see where this goes long term and what the restrictions on public buy-in will be.
Maybe there is commercialization potential in agriculture to reduce animal suffering?

[Liam Akroa @Liam_Akroa]

@BagOfNeurons Fruit fly geneticists go crazy for this

[Liam Akroa @Liam_Akroa]

Counting the days till May @vitalismorg

[Adam Gries @adamgries]

🧵 Elon: “Longevity is an extremely solvable problem”

At Vitalist Bay (May 14 - May 17), we’re solving it!

1K+ pioneers, 100+ speakers, 50+ workshops, 40+ activities, 5 critical health tests

Join us to spark dozens of SpaceXs for longevity!

[Liam Akroa @Liam_Akroa]

Amazing to see ARPA-H pushing to develop some of the most promising technologies for improving human well being and life.

[ARPA-H @ARPA_H]

A first in organ transplantation! Announcing the performer teams for PRINT, our program to bioprint universally matched organs on demand—eliminating chronic shortages, long waitlists, and lifelong medication dependence. 🫀 https://t.co/2RXQfpGp7v

[Liam Akroa @Liam_Akroa]

Curious how @becoming_ai is generating their placental models. Naive or primed huiPSCs-both? What are they implanting into-matrigel? Do they have syncytioblast, cytotrophoblast, and chorion?

Excited to see where this goes. We aren't stitching together frog embryos anymore!

[Becoming @becoming_ai]

How do we go from a single cell to a complex organism?

For 50 yrs experimentally meeting the nutritional demands of a growing organism has been a bottleneck in development.

For the first time, we built placental support and predictive tools to make it possible.

Watch ↓

[Becoming @becoming_ai]

How do we go from a single cell to a complex organism?

For 50 yrs experimentally meeting the nutritional demands of a growing organism has been a bottleneck in development.

For the first time, we built placental support and predictive tools to make it possible.

Watch ↓

[Liam Akroa @Liam_Akroa]

Who is in Saint Louis? Where are the biotech and longevity people in Saint Louis?
I’m trying to map the ecosystem: startups, labs, incubators, students, investors, clinicians anyone in biotech, aging, or regenerative medicine.
Let's connect and build a community!

[Liam Akroa @Liam_Akroa]

@kaimicahmills Great to see someone so bold on these overlooked technologies. Genuinely curious, what makes you so confident in these technologies?

[Liam Akroa @Liam_Akroa]

@ARPA_H Awesome!

Love to see ARPA-H tackling some of the biggest challenges in medicine.

[Liam Akroa @Liam_Akroa]

Calling all bio enthusiasts!

I've managed to land a position as a Supplemental Instructor for an undergrad molecular bio class. I need your best tools, resources, and memes for inspiring undergrads! Image related

[David K. Yang @davidkmyang]

Biopharma's unfortunate challenge is that even the grand vision of treating all diseases is simply not compelling enough for most people.

We need to also develop medicines that elevate everyday life for the already healthy.

[Liam Akroa @Liam_Akroa]

Spending too much time on X is finally getting to me.

[Liam Akroa @Liam_Akroa]

@LivnatJerby @ColumbiaSBI Loved this episode—As an undergrad just learning about immune cell engineering, it was an exciting listen. The Jerby lab's strategy for spacial targeting was elegant and effective. I wonder what engineering strategies could enhance solid tumor penetrance?#SynBio #CancerImmunology

[Liam Akroa @Liam_Akroa]

Had a thought in cell bio lecture covering mitosis today:

Cell State is governed by groups of cooperative and antagonistic proteins in feedback loops. Interactions between these groups across time and space produce cell state.

Is this too general / has no predictive power?

[Adam Gries @adamgries]

Join the Vitalist Longevity Meetup in NYC this Thursday to connect with some of the smartest, most innovative people in Longevity.

Hosted by the incredible @Lrschfr

Retweet and share with your favorite longevity people.

https://t.co/vYg4af0Akn

[Liam Akroa @Liam_Akroa]

Excited to share the second installment of "spare parts", where I cover the different faces of replacement for longevity!

In this installment I tackle artificial organs, an amazing area of research that holds great potential.

Spare parts https://t.co/0YHheAllX2

[Liam Akroa @Liam_Akroa]

Highly recommend to anyone in the area! Vitalism knows how to host a conference.

[Nathan S. Cheng thinks you should work on aging. @realNathanCheng]

📣 JULY 26, TOKYO - We're co-hosting the #1 longevity science and startups conference in Japan! 🇯🇵

Come join us at Tokyo Longevity Summit (co-organized by Vitalism Foundation):👇