Linda Decker

PhD student at the @diz_lab @EMBL researching the mechanobiology of colorectal cancer

[Linda Decker @Lindithium]

@CancerGrand @biorxivpreprint @diz_lab

[Linda Decker @Lindithium]

Excited to present mechanoMaST, our workflow that spatially maps AFM-based mechanics to Spatial Transcriptomics, as a preprint and in a selected talk today at the @CancerGrand Spatial Biology Conference!

@biorxivpreprint: https://t.co/b11Oo3vRym
@diz_lab

1/6

[Linda Decker @Lindithium]

@huanting_ong @nano_jenn @MBIsg Huge thanks to all authors Dmitrii Olisov | Nikolai Schleussner | Hendrik Wiethoff | ProfileThomas Schmidt | Henrik Nienhueser |Thomas Moritz Pausch |Jan Oliver Korbel |Alba Diz-Munoz
@diz-lab.bsky.social
@embl.org
And patients and their families!
6/6

[Linda Decker @Lindithium]

@huanting_ong @nano_jenn @MBIsg Together, both studies demonstrated that #spatialomics can now be extended by mechanical measurements. We highlighted that tissue stiffness matters across species, ages and pathologies and should therefore be considered more regularly in clinical and fundamental research.
5/6

[Linda Decker @Lindithium]

We probed 20 µm, adjacent cryosections from 10 colorectal cancer liver metastasis patients. Using AFM and Visium Spatial Transcriptomics we created high-resolution stiffness and gene expression maps that we spatially registered via a custom image registration pipeline.
2/6

[Linda Decker @Lindithium]

Returning from #LINO25 inspired by science. I am very grateful to the Nobel Laureates, organisers, guests, and fellow Young Scientists for fostering such an open, supportive environment filled with curiosity and drive for meaningful research.

[Health + Life Science Alliance Heidelberg Mannheim @ResearchLifesci]

Vom 13. - 17.5.24 🧪🧬⚗️
#AkaMi in der Peterskirche mit 5 spannenden Vorträgen @Lindithium @KGoepfrich @DenisSchapiro
@ResearchLifeSci
Bitte teilen!

#lifesciences #gesundheit #lifesci #healthscience #medicalresearch #biochemistry #biomedicine #researchalliance #Innovation

[Rubén Tesoro Moreno @TesoroRuben]

First ever poster presentation done ! #EESMechanobiology is so much fun and the talks and science is amazing! 🤩 Looking forward to day 3!

Btw, Check @Lindithium (poster 56) tmw on the cancer Biomechanome

[EMBL @embl]

Congratulations Alba Diz-Muñoz!

The EMBL Heidelberg group leader received the @cziscience Ben Barres Early Career Acceleration Award. It will support her research on harnessing mechanics to immunomodulate microglia and fight neurodegeneration.

https://t.co/GxFBdKvK3o

[Linda Decker @Lindithium]

I am looking forward to presenting the importance of mechanobiology in an accessible way. If you are visiting the #BUGA23 consider stopping by for my talk: Mechanomedizin – Warum wir nach “Weichmachern” für Tumore suchen
https://t.co/nKzgq4kzZP

[Health + Life Science Alliance Heidelberg Mannheim @ResearchLifesci]

Come and visit us on 30 Sept and 1 Oct at our booth at the @BugaMannheim. Check out the program https://t.co/Xtl0pQiTt1 jointly arranged by all Alliance institutions @dkfz @embl @mpi_mr_hd @UniHeidelberg @uniklinik_hd @unimedizinma @zi_mannheim. Talks will be in German.

[Linda Decker @Lindithium]

Thank you @ResearchLifesci for organizing the Science Splash. It was an amazing event for networking, knowledge exchange and hearing about exciting research.

[Health + Life Science Alliance Heidelberg Mannheim @ResearchLifesci]

Get an impression of the first Alliance ScienceSplash 2023 with >100 researchers from all partner institutions @DKFZ @EMBL @mpi_mr_hd @UniHeidelberg @unimedizinma @UKHD @zi_mannheim. Thanks to all participants, especially all speakers! https://t.co/Cp2ButddtA via @YouTube

[EMBL PhD Symposium @EMBLPhDSymp]

🌟Power of Many🌟
Each year the PhD students of EMBL can pick the most promising topic in current biology for the EMBL PhD Symposium.
This year we’ve chosen to organise a symposium about collective behaviour across scales. Join us 20th to 22nd of November!
#EMBL #emblphdsymposium

[Linda Decker @Lindithium]

I am excited to finally be on twitter and share these beautiful images with you!

[EMBL @embl]

Have you suffered from a runny nose recently? Mucus – more colloquially known as snot – often contains antimicrobial substances. Mucus in the mouse colon can be visualised using Alcian blue staining, as imaged here by EMBL predoctoral fellow Linda Decker.
https://t.co/y04b9UOqe8