Lohmann lab

We at the Synapse and Network Development Lab study how visual cortex neurons make synapses and communicate with each other to prepare the brain for vision.

[Andrew Payne @Andrew_C_Payne]

E11 Bio is excited to share a major step towards brain mapping at 100x lower cost, making whole-brain connectomics at human & mouse scale feasible (🧠→🔬→💻). Critical for curing brain disorders, building human-like AI systems, and even simulating human brains. 1/N 🧵

[Lopez_Bendito Lab @GLB_Lab]

Attention📢!! The #SPONT2024 website is now live! Check out the fantastic speaker lineup and don't miss the early registration date. We look forward to see you there! @GuilleLBendito @Lohmann_lab @FellerMarla @NeuroAlc @CSIC
https://t.co/NetMtWfr0Y

[Neural Computation Lab @NeuralCompLab]

Have you ever looked at traces from an extracellular recording and wondered what kind of neurons you are recording from? Five labs across three continents working with two species joined forces to solve this decades-old problem in systems neuroscience. 🧵

[Levelt lab @Leveltlab]

Koen and Nora's paper on Chandelier cell function in the primary visual cortex is now published in eLife! Congrats to all authors!

[Vidhya Rangaraju, PhD @RangarajuVidhya]

Starting the new year with our lab’s first paper in @NatComms!

🪫Synapses are powerhouses for plasticity & memory formation, but they are also energy hogs.

🔋VAP is our newfound anchor that tethers mitochondria near synapses, providing a critical local energy source for memory.

[NIN @NIN_knaw]

We would like to congratulate the @Leveltlab, Kole lab and Lohmann lab on receiving the NWO ENW-M grant 👏

https://t.co/p5cs2uzs5U

[Rogier Min @rogiermin]

What do astrocytes, cannabinoid receptors and brain development (in particular critical periods) have to do with each other??

Read all about it in a new @biorxiv_neursci preprint from my postdoc time in the @Leveltlab

And in the summary below!🧵 (1/10)

https://t.co/MOSQp5ZDeS

[Lohmann lab @Lohmann_lab]

Bollmann, Modol, Tressard et al. show hub neurons in the developing barrel cortex in vivo.

[Nature Neuroscience @NatureNeuro]

Single GABAergic, but not glutamatergic, neurons influence population dynamics in the barrel cortex of mouse pups, acting as "hub neurons" that exert an inhibitory influence on both spontaneous and sensory-evoked population bursts

https://t.co/NE5ZSb4z2C

[Lohmann lab @Lohmann_lab]

We offer an exciting internship opportunity within our lab! Gain hands-on experience in imaging and electrophysiology while studying acetylcholine modulation of the developing visual cortex. Apply here: https://t.co/ovn7ipaffa

[Lohmann lab @Lohmann_lab]

Developing synapses form in dendritic domains. At postnatal day 9, some synapses (dots) are already organized in domains (color), which contain high-activity synapses (black outlines). At P12 synapse numbers and activity increase and most synapses are now in domains.

[Lohmann lab @Lohmann_lab]

We were surprised to find how precisely connected developing neurons are! Our new study shows that synaptic inputs of pyramidal cells in the visual cortex are clustered already days before eye opening. #neuroscience #synapse #braindevelopment https://t.co/g71YXtHZnA

[Lohmann lab @Lohmann_lab]

Synaptic inputs on dendrites of a postnatal day 12 visual cortex neuron in layer 2/3 in vivo resulting from spontaneous activity of the developing neuronal network. 6x real time.