Luca Del Prete MD

HPB and Liver Transplant Surgeon - Policlinico Hospital, Milan, Italy;
Research Fellow in Liver Transplantation at the Cleveland Clinic, Cleveland - OH

[Liver Fellow Network @LiverFellow]

Low sodium, high stakes 🧂⚠️

Why does hyponatremia occur in cirrhosis, how should it be evaluated, and when does treatment become urgent?
Check out this #LFN Back to Basics review on hyponatremia in cirrhosis!

Author: Dr. Victoria Kusztos ✍️

🔗: https://t.co/lXuy3bRtQT

[Liver Transplantation Journal (LTxJournal) @LTxJournal]

Ascites is not one phenotype. In LT candidates, 3 reproducible phenotypes emerged. Vasodilatory-synthetic dysfunction carried ~3-fold higher AKI risk despite MELD 3.0 adjustment, but no higher waitlist mortality.

#LiverTwitter #Ascites #Transplantation

https://t.co/j2TCOFzvk2

[Liver Transplantation Journal (LTxJournal) @LTxJournal]

Overcoming hepatic artery variations: Arterial reconstruction strategies to expand normothermic machine perfusion in liver transplantation

https://t.co/hVHs2aKQYw

[Liver Transplantation Journal (LTxJournal) @LTxJournal]

Risk factors of biliary cast syndrome among liver transplant recipients

https://t.co/zuUx41MM97

[Liver Transplantation Journal (LTxJournal) @LTxJournal]

Overcoming hepatic artery variations: Arterial reconstruction strategies to expand normothermic machine perfusion in liver transplantation

https://t.co/hVHs2aKQYw

[Liver Transplantation Journal (LTxJournal) @LTxJournal]

A simple intraoperative score incorporating thromboelastometric parameters predicts early reoperation for bleeding after liver transplantation

https://t.co/d6HaD1INPV

[Liver Transplantation Journal (LTxJournal) @LTxJournal]

Liver transplantation indications and strategies in polycystic liver disease: A European survey

https://t.co/DEV80k3XYO

[Transplantation @TransplantJrnl]

A new global milestone in transplantation has been reached: A total of 173,727 solid organ transplants were performed worldwide in 2024, which is the highest number ever recorded and represents a 2% increase on 2023.
Download this freely available paper! https://t.co/TdJrLCNzwy

[UofT Surgical Oncology @UofTSurgOnc]

🎉 Our brilliant new #SurgOnc clinical fellows have already been at work for a month!
Welcome to Toronto and the program @aleborghiMD 🇮🇹 @DrShellyLuu 🇨🇦 @julielaMD 🇨🇦 & Alberto Riojas 🇲🇽🌟

[Thomas Forbes @TL_Forbes]

Major step forward toward cure for diabetes in trial led by Dr Trevor Reichman, Director of Pancreas & Islet Transplant Program ⁦@UHNTransplant⁩ ⁦@UHN_Surgery⁩ ⁦@UHN_Research⁩ ⁦@UHN⁩ https://t.co/M8OlibybAS

[StanfordAbdTxp @StanfordAbdTxp]

🧒🩺 New from Drs. @AmandaJensenMD & Carlos Esquivel in @LTxJournal: In pediatric liver transplants, choledochoduodenostomy (CD) had the fewest biliary complications—lower stricture & leak rates than traditional options. CD is safe & may be superior.

🔗: https://t.co/MyKqG9rhGF

[Giovanni Marchegiani @Gio_Marchegiani]

IPMN 🍇 without HRS and long term risk of cancer development

🇯🇵 2.5k pts > 5 years surveillance

🫧 IPMN size and growth predict cancer within 5 years

🤏 MPD diameter at 5 years predicts cancer after 5 years

https://t.co/dNeBthc6QU

[The Lancet @TheLancet]

Pancreatic cancer, often linked to smoking, obesity and diabetes, is predicted to become the 2nd leading cause of cancer-related death by 2030.

A recent Seminar discusses the need for novel therapies & future directions for research: https://t.co/IQNCCl8FJY

[M Velia Antonini @FOAMecmo]

Deceased donor liver utilisation & assessment, consensus guidelines from ELITA including practical considerations/recommendations on:
🚧 adverse outcomes to be used to define suitability for #transplantation with conventional SCS alone
⚖️ donor & graft factors to define liver suitability for #Tx after SCS for DBD or SRR & conventional SCS for DCD
⚖️ intended recipient & suitability for #tranplantation
🩸in situ normothermic regional perfusion
🌡️❄️ex situ hypo/normothermic machine perfusion
🩸perfusion strategy for DBD & DCD livers
⚙️ combining perfusion vs isolated strategies
📏parameters to be measured during NRP, NMP, HOPE & combined modalities for livers assessment
🔍assessment of hepatocytes & biliary tree during perfusion
@ESOTtransplant @gabriel_oniscu @CFondevila @hessheimer
🖇️ https://t.co/9BFAgS12U3

[Transplantation @TransplantJrnl]

Normothermic regional perfusion (NRP) boosts organ recovery, but ethical concerns slow adoption. A scoping freely downloadable review explores key debates on donor harm, consent, trust, & justice. Can ethical challenges be resolved? #TXPforAll #OpenAccess https://t.co/FDSbq3Udb4

[Liver/Intestinal Community of Practice - AST @AST_LICOP]

Update on Portopulmonary hypertension guideline by International liver transplantation society
📌Hemodynamic definitions
📌Management approaches
📌POPH MELD exception criteria
📌Long-term outcomes
#livertwitter
https://t.co/lJFuzY9gF1
@AnjanaPillaiMD
@HowardTLeeMD
@LizzieAbyMD

[Giovanni Marchegiani @Gio_Marchegiani]

The hard part of the whipple is done 💪time for the H-J !!! But do not let the attention drop… it can be tricky! 😅

🎥 Video grading bile duct anastomoses during robot PD

🐸 Bile leak rate 7% predicted by video!

🤖 Tool for teaching / learning curve

https://t.co/LLUg7rysIA

[Luca Del Prete MD @LucaDelPrete9]

@StanfordAbdTxp @KazuS123456789s @StanfordSurgery Congratulations!!

[Liver Transplantation Journal (LTxJournal) @LTxJournal]

Co-producing a health advocate intervention for pediatric liver transplant recipients using human-centered design @UCSFLiverCenter @DoctorSharad @johnbucuvalas @JVittorioMD
https://t.co/RwnYzv8C5M

[Annals of Surgery @AnnalsofSurgery]

ChatGPT-4 demonstrates strong accuracy in grading surgical complications using the Clavien-Dindo classification. While it holds promise for automating postoperative data analysis, human oversight is still critical.
https://t.co/GmUWWYc0VV