My first ever project. So happy to see this published! Viruses can do the craziest things - even remodeling ribosomes🦠
Check out the newest paper from the Lee lab here
New research by @DanaFarber’s Amy Lee, PhD, and Max Fels, PhD, published in @CELL reveals that giant DNA viruses encode a distinct and functional IF4F translation-initiation complex to drive protein synthesis, thereby blurring the line between living cells and viruses.
Read more: https://t.co/HsN5wisY1U
👏 Big applause for our scholarship winners as we wrap up Autoimmunity & Autoinflammation in Keystone! Proud to support the next generation of scientists through the Keystone Symposia Future of Science Fund. Learn more: https://t.co/4NuGmKRavW @v_hornung#KeystoneSymposia
🧵1/5 I'm so proud to share these incredible findings from our collaborative work with @amara_lab & @jreguera lab about Alphaviruses, particularly the chikungunya virus!! Highlights in the 🧵👇
https://t.co/KGLAzoyJGN
Human mRNAs form globules in 3D and are prepared for export by the transcription-export complex. We are excited to share this and more mechanistic insights in our newest work, co-lead by the fantastic @bpachecofiallos and @MVorlandr. https://t.co/3gek1QRSu2 (1/9)
eIF5A2, despite sharing 84% amino acid homology with eIF5A1, was found to play no role in mRNA translation. Instead, it regulated gene expression at the transcriptome level, revealing a formally uncovered role in anti-viral activity.
https://t.co/LdXQstS9zi