Lydia L Simpson

British Heart Foundation Post-Doc Fellow | @CardioNomics Lab, University of Bristol | Autonomic Cardiovascular Control | Views are my own

[Lydia L Simpson @LydSimpson]

Article in @JPhysiol: Why does 🧠 blood flow increase progressively during running?

We demonstrate
1️⃣Foot-strike-induced pulsatility oscillations do not alter MCAv.
2️⃣Cerebrovascular reactivity to hypocapnia is ⬇️ during running.@BristolUni @uniinnsbruck

https://t.co/8uVh5mTDmI

[Experimental Physiology @ExpPhysiol]

Can post-exercise hot-water immersion induce a cross-adaptation effect enhancing exercise performance in acute hypoxia? @PatrickRod_PhD, @LydSimpson, @Justin_lawley, Hecksteden (University of Innsbruck) and Lesmana (@unpofficial_) investigate...

📜 https://t.co/rtCLoRYvcy

[Denis Wakeham @DenWakeham]

Really happy to see this published in EJHF. Joey, Chris and I show that middle-aged adults with severe obesity present with absolute hypervolemia, relative hypovolemia and disproportionate LV enlargement. @utswheart @UTSWMedCenter @texashealth @IEEMPHD
https://t.co/HNhkU4C7Un

[Denis Wakeham @DenWakeham]

Really happy to see our paper published in @JHypertension. @Deoliveiragdc and I show that the BP pressure response to exercise is not different between hypertensive adults with LVH and healthy controls when normalized for VO2.
https://t.co/C8YHiVMabv

[Journal of Physiology @JPhysiol]

Julian C. Bommarito & Philip J. Millar (@UofG_HHNS) offer this #Perspective 'Metabolic override: Adding neuropeptide Y to the list of vasoconstrictors attenuated by exercise' based on the work of Wakeham et al. (2025) 💭

🔗 https://t.co/v1tXZk62m0

[NeuroV̇ASQ̇ - Integrative Physiology Lab. @NeuroVASQ]

New perspective from @lauro_vianna:
When the #lungs speak to the #brain: a new reflex pathway in the neural control of circulation during #exercise?

@JPhysiol 📝

https://t.co/Tgy9102E8a

[Journal of Physiology @JPhysiol]

In this recent study, Denis J. Wakeham (@UTSWMedCenter) et al. investigated functional sympatholysis of neuropeptide Y-mediated #vasoconstriction in humans 🫀🏃

📜 Read the #Research here: https://t.co/vDQOCzJDiy

[Denis Wakeham @DenWakeham]

Happy to share our recent paper published in @JPhysiol that shows, for the first time in humans, that Neuropeptide Y mediated vasoconstriction is sensitive to functional sympatholysis, to a similar degree that is alpha-adrenergic vasoconstriction.
https://t.co/m6GrEBwQP8

First of many papers in this area from Chris M. Hearon Jr.'s lab at @IEEMPHD (@texashealth) and @UTSWMedCenter. Thanks to our collaborators, Paul Fadel and Scott Davis, on this project.

[AJP-Heart and Circ @ajpheartcirc]

A team at @uwsmph brings us all an #OpenAcces #ArticleinPress! #Biological sex influences relationships between #cerebral pulsatility and white matter hyperintensities in #aging adults (Erin Moir et al.):

https://t.co/Z6Nc41VVYY

[Zoe Adams @zoehadams1]

Our review on androgens and cardiovascular control in polycystic ovary syndrome is out! Read about what we know (and what we don't) about how androgens impact cardiovascular health in #PCOS 🫀@lordylaa @JPhysiol https://t.co/7KioJCpF0u

[Patrick Rodrigues @PatrickRod_PhD]

🚨 Hot off the press!

🔥Heat to hypoxia cross-adaptation ⛰️

Our new study shows that 6 weeks of post-exercise hot water immersion (HWI) can boost exercise performance in acute hypoxia. 🚴‍♂️🛀🔥
@sportaerztin @Justin_lawley @LydSimpson
@ExpPhysiol https://t.co/SQFZhGIpjP
@waikato

[Denis Wakeham @DenWakeham]

Great to see this published in @ExpPhysiol working with Mike Nelson. The paper extends the assessment of central arterial stiffness and wall mechanics (strain and strain rate) from ultrasound to MRI using a cine collected in every cardiac MRI ever taken.

https://t.co/7oJxLkx3kO

[Lydia L Simpson @LydSimpson]

The carotid chemoreflex contributes to high resting BP in young people with untreated hypertension, but does not play a role in exaggerated exercise BP responses

⁦Hinton et al @JPhysiol⁩ ⁦@UoBrisPPN⁩

#chemoreflex #hypertension #exerciseBP https://t.co/SpTfFDIbuh

[Journal of Physiology @JPhysiol]

Sandra Neumann (@UoBrisPPN) et al. investigated #cerebral blood flow during simulated central #hypovolaemia in people with hypertension in this recent #Research article 🫀 🧲

📜 Read it here: https://t.co/3t0D0CYIbr

[Lydia L Simpson @LydSimpson]

Hypertensives with normal vertebral artery anatomy can tolerate ⬇️ in 🧠 blood flow during central hypovolaemia

Those with vertebral artery hypoplasia evoke greater ⬆️ in systemic vascular resistance to preserve CBF.
⁩ ⁦⁦⁦@UoBrisPPN⁩ https://t.co/PPwTm4ZGhJ

[Tom Nightingale @Tnightingale10]

Consider joining us at @unibirmingham @UBSportExR for applied and practical learning on the Clinical Exercise Physiology MSc.

📢Currently recruiting for September 2025!

Contributors: @kathskth @SamLucas_PhD @joannachapillon, Rich Powell, myself and guest lecturers

[Lydia L Simpson @LydSimpson]

@HartEmhart86

[Lydia L Simpson @LydSimpson]

❗️Funded PhD❗️
Join @CardioNomics⁩ ⁦@UoBPPN⁩ ⁦

Under Stress: Why Women of Black African and Black Caribbean Heritage Face Elevated Risk of #Hypertension and #Stroke

Open to UK students of Black African, Black Caribbean or mixed Black heritage https://t.co/iwhHAbWyof

[Dr John Fernandes @DrJFTFernandes]

Funded PhD with @HartEmhart86 @LydSimpson looking at hypertension in Black African and Caribbean women🩺🫀

Open to UK-domiciled, home fee applicants of Black African, Black Caribbean or other Black or mixed Black heritage.
@pubhealthjobsuk @JobsinSportSci
https://t.co/PFZBYYQ7zn

[Bristol Heart Institute @BHIBristol]

The BHI is hosting the Bristol Heart Festival, a vibrant celebration of heart health and cardiovascular advancements, to be held at the historic Wills  Memorial Building on Thursday, 13 March 2025. Open to the public. https://t.co/23BQagcdtD