M. Alexander Otto

Physician Assistant, journalist. MIT fellow, Medscape/
WebMD, McClatchy, Bloomberg, Washington Post.

[M. Alexander Otto @MAlexanderOtto]

@PCFnews https://t.co/k66iCRO2Wx

[M. Alexander Otto @MAlexanderOtto]

important study for oncologists

https://t.co/PdlN59TZlo

[M. Alexander Otto @MAlexanderOtto]

[tweet to keep acct active]

[M. Alexander Otto @MAlexanderOtto]

The takehome on CAR-Ts is that it cures maybe 30% of lymphoma patients who would have died otherwise. They reprogram WBCs to attack it. Holy Grail now is to do that trick against pancreatic, lung, ovarian, and every other kind of cancer, but they're different. 40% chance.

[M. Alexander Otto @MAlexanderOtto]

Wow, thanks for still following me! I'm a Medscape oncology reporter now. Okay, the latest is that CAR-T is the magic bullet for cancer. I hope that's true, but give it a 40% chance. In the meantime you derms, don't trust that melanoma gene test!

https://t.co/9MiY9H0deg

[M. Alexander Otto @MAlexanderOtto]

Fresh of the press. Indeed, it is a nasty little bug, but things are looking up on Long Island, anyways. Can you imagine 70 people all intubated at once? Like a sci-fi nightmare...
@MDEdgeTweets @AmerMedicalAssn @Medscape
@ivanoransky @hmkyale
https://t.co/qKf5eZAwa8

[M. Alexander Otto @MAlexanderOtto]

Hey, if someone has a positive nasal swab and dies in NYC , they are counted as having died from COVID-19. NYC health dept. told me that today. Seems to be how we are doing it in the U.S. Raises legit questions about the numbers. @MDEdgeTweets
@MSLUnlimited
@ivanoransky

[M. Alexander Otto @MAlexanderOtto]

@jeffbcraven @MDEdgeTweets it's a busy little beast

[M. Alexander Otto @MAlexanderOtto]

We were the first news outfit to report this. Yes, COVID-19 has skin manifestations! @MDEdgeTweets #Covid_19

https://t.co/egaQS1g5fm

[M. Alexander Otto @MAlexanderOtto]

Routine musculoskeletal exams have to be added to regular Down syndrome checkups. Here's why. (Presented at ACR 2019) @ACRheum @irishexaminer @MDEdgeTweets @DSAInfo @NDSS @GDSFoundation @DSiupdate @DownSyndromeIRL @CdnDownSyndrome

https://t.co/XnXaNiuavU

[M. Alexander Otto @MAlexanderOtto]

It's a breakthrough for tuberous sclerosis infants, preventing seizures and major brain damage. It will be standard practice in the US pretty soon. Presented at AES 2019. @amepilepsysoc. @EDSGMUW @MDEdgeTweets @AAPCA2 @tsalliance

https://t.co/M69aVb1pOK

[MDEdge @MDEdgeTweets]

AN EXCITING ANNOUNCEMENT: We are thrilled to share that MDedge has joined forces with the @Medscape Network to create an even more valuable destination for physicians and health care professionals. Together, we look forward to building a deeper, richer experience for you.

[M. Alexander Otto @MAlexanderOtto]

Plaquenil 400 mg/d starting on pregnancy week 10 prevents congenital heart block in anti-Ro positive SLE women. So it's saves baby's lives, and will be standard of care. Take a bow, NYU's Dr. Peter Izmirly. #ACR2019 @MDedgeRheum @nyuniversity
https://t.co/XwSZ5GvP6d

[M. Alexander Otto @MAlexanderOtto]

Down syndrome arthritis is more aggressive than JIA, but it often takes a year or more before it's diagnosed, and by then, kids are in a bad way. Routine musculoskeletal exams must be added to DS guidelines, says Dr. Jordan Jones #ACR2019 @MDedgeRheum

[M. Alexander Otto @MAlexanderOtto]

Elevated adenosine deaminase 2 blood test 86% sensitive, 93% specific for MAS in systemic JIA, blowing other markers out of the water. Could be a game changer for the detection/treatment of JIA's nightmare complication. Thank you, Dr. Pui Lee! #ACR2019 @MDedgeRheum

[Kari Oakes @KariOakes]

We did a post-#ESC2019 podcast from my @Airbnb dining room table in Paris! Lots of fun with smart colleagues. Part 1 here: SGLT-2 inhibitors and more practice changing data from ESC 2019 https://t.co/yf6wTuJsl7 @MDEdgeTweets @MDedgeCardio

[M. Alexander Otto @MAlexanderOtto]

@Marina_Leiva_G @drjosflynn @AHAMeetings @MDedgeCardio @MDEdgeTweets Welcome to the United States of America :-)

[M. Alexander Otto @MAlexanderOtto]

It probably makes more sense to use ambulatory blood pressure, instead of office pressure, to guide HTN treatment, but reimbursement is a problem in the U.S. One of many insights from #Hypertension19 @AHAMeetings @MDedgeCardio @MDEdgeTweets

[M. Alexander Otto @MAlexanderOtto]

@Marina_Leiva_G @drjosflynn @AHAMeetings @MDedgeCardio @MDEdgeTweets treating based on 24 hour ambulatory blood pressure values, not the in-office values. the ambulatory pressures give a truer indication of patients real-world BP values.

[Sharon Worcester @SW_MedReporter]

IASLC: MDedge coverage begins now with opening press conference! Stay tuned for news and highlights from #WCLC19 in Barcelona! @MDEdgeTweets

[M. Alexander Otto @MAlexanderOtto]

... and the write up of the study from Dr. Cohen and colleagues, visceral adiposity vs. masked hypertension #hypertension19 @jordy_bc @ahameetings @MDEdgeTweets

https://t.co/gOvLUAzHqU