"Lung clearance index (LCI) and steroid response in paediatric severe asthma" coming soon to Pediatric Pulmonology! My first foray outside my comfort zone of PCD as first author, and I couldn't be more pleased it's been accepted.
Successful #LCI use in preschool #cysticfibrosis hypertonic saline intervention study: #LCI 0.6 less Unknown minimal clinically imp difference limits interpretation. Sustained better LCI trajectory over years may prove real benefit @ATSPeds@CF_Foundation
https://t.co/0mYz86096d
Really exciting work on MRI and LCI, helping us to see the ventilation unevenness that we can measure with lung function tests. Watch this space! Thanks @LouieLaurie #respiratoryphysiology#ecfs2019
Felix Tatjen discussing results from the SHIP study looking at hypertonic saline in pre-school children and its effects on LCI. ✨Significant difference in LCI supporting potential use as an early intervention. #ecfs2019
One-year evolution and variability in multiple-breath washout indices in children and young adults with primary ciliary dyskinesia https://t.co/DTPIxcI2Jx
Spirometry is used to diagnose and manage airway disease such as asthma and COPD, but relates poorly to symptoms, lacks sensitivity and is effort dependent. FOT and MBNW are emerging clinical lung function tests that help us dismantle disease mechanisms. https://t.co/4aDQ19ZDXA
The issue of which tracer gas to use for multiple breath washout testing is a tricky one. See link below for our comments on a recent paper looking at this...
https://t.co/cSvTJXZBXB
Spirometry does not have a short-term effect on multiple-breath washout outcomes, thus allowing greater flexibility for implementation into clinical practice https://t.co/KfIttYO5TE