MatthiasFellner

Understand protein structure-function relationships and use this knowledge to answer fundamental questions of chemistry/biochemistry at the University of Otago.

[MatthiasFellner @MFellnerLab]

Just out: Covalent isothiocyanate inhibitors of macrophage migration inhibitory factor as potential colorectal cancer treatments. Great collaborative effort between @OtagoPharmacy @joel_tyndall , @OtagoBiochemist and @otago Chemistry
https://t.co/6TbfopBpN7

[MatthiasFellner @MFellnerLab]

New @BiochemistryACS paper about one of my favorite enzymes ever - Structural, Spectroscopic, and Computational Insights of the Ethylene-Forming Enzyme. Collaboration between @MSU_BMB @michigantech and myself at @OtagoBiochemist https://t.co/kLcDUw3Rwm

[MatthiasFellner @MFellnerLab]

Structures just released
https://t.co/02mOEJW0zc
https://t.co/Psyt4YE0y0
determined in collaboration with @Stanford @mbogyo and my lab at @OtagoBiochemist - JACS paper on Probes for Specific Detection of Staph Infections
https://t.co/tsUazuuCBr @JeyunJo @TulsiUpadhyay5 +others

[Matthew Bogyo @mbogyo]

Check out our latest covalent probes for imaging Staphylococcus aureus infections published @J_A_C_S. Great work from @JeyunJo and @TulsiUpadhyay5 and collaborators. https://t.co/arQvpJj9bX

[Tulsi Upadhyay @TulsiUpadhyay5]

Thrilled to share the news!! Thanks Matt @mbogyo, for giving this fantastic opportunity to work on this project. Enjoyed teaming up with @JeyunJo, @MFellnerLab and all our collaborators 🙌 Thanks @ec_woods, @NikkiPedowitz, @SijieWang5 for helping us with this project!!

[Jeyun Jo @JeyunJo]

Exciting news from our recent research with @TulsiUpadhyay5 on oxadiazolone-based probes targeting FphE, a S. areus specific serine hydrolase. This is a result of great collaboration with @MFellnerLab, the Valdez lab, Joanna Jaworek-Korjakowska, and the team at @mbogyo lab.

[Matthew Bogyo @mbogyo]

Looking for a new covalent electrophile for serine and cysteine nucleophiles? Check out this great work by ⁦@JeyunJo⁩ and ⁦@TulsiUpadhyay5⁩ developing an oxadiazolone based probe for the S aureus serine hydrolase FphE. https://t.co/v0obEQGfJd

[MatthiasFellner @MFellnerLab]

1. characterization of a highly conserved S. aureus serine hydrolase. https://t.co/uSY7x90bUP
@OtagoBiochemist (Annabel Walsh) OtagoChemistry (Sutherland, Tan) & international collaborators A. Bakker, @mariovdstelt, @NatMart_Chembio, @NadiaAftab18, S. Dela Ahator @ChristianSLentz

[MatthiasFellner @MFellnerLab]

One week left to apply #postdoc #position in #biochemistry on #research into #peptide & #enzyme via #phage in ##infectiousdisease at #university @OtagoBiochemist in #NewZealand and #Shanghai #SIMM
Details: https://t.co/yeexj27HK6

[MatthiasFellner @MFellnerLab]

We are looking for a Postdoctoral Fellow to create peptide tools for the treatment & diagnosis of infectious diseases at the University of Otago & Shanghai Institute of Materia Medica.
Funded by New Zealand Maurice Wilkins Centre Starting September
Details https://t.co/yeexj27HK6

[MatthiasFellner @MFellnerLab]

We are looking for an Assistant Research Fellow to create Staphylococcus aureus samples for metabolomics to identify the roles of serine hydrolases in biofilms (https://t.co/YnrnngQ9T8)
University of Otago, Dunedin, New Zealand.
Starting in July
Details: https://t.co/OVgIP1MUgG

[Otago Biochemistry @OtagoBiochemist]

Bacterial biofilm therapeutics project wins Marsden Fund support https://t.co/sDEbeXB52S

A project investigating new ways to fight deadly bacterial biofilms has won a Marden Fast-Start fellowship for its lead researcher, Otago biochemist Dr Matthias Fellner.

Matthias is seeki…

[Otago Biochemistry @OtagoBiochemist]

Otago researchers set to tackle health issues with Career Development Awards https://t.co/QeWBxPtBZY

From a global health crisis to Aotearoa’s health inequity – University of Otago projects awarded Health Research Council funding will benefit those at home and around the world…

[Otago Biochemistry @OtagoBiochemist]

$3.8 million to Otago researchers in Career Development Awards https://t.co/yG7ZluWto7

The Health Research Council has awarded 19 Otago researchers almost $3.8 million in Career Development Awards.

These awards help launch research careers through a wide range of master’s and…

[Marsden Fund @MarsdenFund]

Taputapu kē! Dr Matthias Fellner🧑‍🔬 @MFellnerLab @OtagoBiochemist @otago has been awarded a #MarsdenFund Fast-Start to study how #Staphylococcus aureus 🦠 use biofilms in antibiotic 💊 resistant bacteria #infection s🏥. #staph #AntibioticResistance
https://t.co/klXgWR8K1T

[Louise Bicknell @bicknell_l]

Really excited to have our paper describing mutations in histone H4 now out - a fantastic collaboration with @GijsvanHaaften and lots of families around the world. Now investigating the mechanism thanks to @MarsdenFund support!

[Louise Bicknell @bicknell_l]

@GijsvanHaaften @MarsdenFund Thanks also to @MacePeter for helping with the structural interpretations of these mutations within the nucleosome!

[MatthiasFellner @MFellnerLab]

Newly discovered #Staphylococcus aureus serine hydrolase probe and drug targets
https://t.co/95blTPPptY
My latest review of ten S. aureus protein targets for probe & drug development. Looking forward to new advances @mbogyo @ChristianSLentz and myself @OtagoBiochemist.

[MatthiasFellner @MFellnerLab]

Excited to share my latest paper in #JournalofLifeSciences on #Cesium binding in #protein #crystals based on work between @MSU_NatSci and @OtagoBiochemist
https://t.co/vjdfFttu1V
Consider #caesium in your #crystallography experiments to improve #diffraction or solve #phases.

[MatthiasFellner @MFellnerLab]

Altered structure and dynamics of pathogenic cytochrome c variants correlate with increased apoptotic activity
https://t.co/CNcu5c3MZo
Our latest work hot off the press from @OtagoBiochemist. Thanks @parakra, KD, @ItamarKass, @gnljameson, SMW & @Liz_Ledgerwood