Michael Levin

🫀🧬 Cardiologist and genetic epidemiologist @PennCardiology and @VAPhiladelphia focused on translating human genetic insights into better cardiovascular care

[Michael Levin @MGLevin]

🚨 Our work exploring polygenic risk scores for Coronary Heart Disease is now out in @JAMA_current and presented at #AHA24 by all-star @SarnoffCardio fellow @sabramowitz_:
https://t.co/AJ5WKsYbBs

[Krishna Aragam @KrishnaAragam]

In @JAMA_current, we report that a single African ancestry-enriched CD36 variant (Y325*) contributes more to the population burden of dilated cardiomyopathy (DCM) in individuals of African ancestry than TTN truncating variants or other known DCM genes.

https://t.co/HofkRxFaLA

[Pradeep Natarajan @pnatarajanmd]

Very excited to share our preprint led by @MGLevin @skoyamamd @jakob_woerner & with @damrauer assessing genome-wide pleiotropy of >1,000 clinical traits across ~1.7M individuals with nearly 30K locus-trait associations!
https://t.co/hJChZPSYNm @medrxivpreprint

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[PennCVI @PennCVI]

CVI's Highlighted #PapersoftheWeek
https://t.co/ZmaYDfURPc

[Katalin Susztak @KSusztak]

Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum | ⁦@NatureGenet⁩ https://t.co/qtpy6lTnRc

[Penn Cardiology Fellows @PennCVFellows]

Check out this editorial just published in @JAMACardio by our very own💫@PennCardiology fellow Anthony Anguiera & @sabramowitz_ under the mentorship of the one & only @MGLevin!

Unfolding the Link Between Transthyretin Stability and Survival
https://t.co/KPDs4N9Svm

[PennCVI @PennCVI]

CVI's Highlighted #PapersoftheWeek
@MGLevin
https://t.co/FfKwlIplrK

[Penn Medicine @PennMedicine]

New research by @damrauer & @MGLevin suggests that polygenic risk scores may provide conflicting results for detecting heart disease risk. https://t.co/42FCAFOrAa

[Sarah Abramowitz @sabramowitz_]

Now out in @JAMA_current: How well do individual risk estimates from different CHD polygenic scores agree? Grateful to work on this with a dream team of mentors and co-authors @damrauer @MGLevin @bpasaniuc @MarylynRitchie @dokyoon_kim @bvoight28 @BoulierKristin @karlkeat

[Michael Levin @MGLevin]

14/ To learn more,
- Check out this editorial: https://t.co/goumqQ1XGo
- Listen to this AI-generated podcast summary: https://t.co/6OCgFdZtDO

[Michael Levin @MGLevin]

🚨 Our work exploring polygenic risk scores for Coronary Heart Disease is now out in @JAMA_current and presented at #AHA24 by all-star @SarnoffCardio fellow @sabramowitz_:
https://t.co/AJ5WKsYbBs

[Michael Levin @MGLevin]

13/ It was fun working with the team:
@sabramowitz_, @damrauer, @BoulierKristin, @karlkeat, @MarylynRitchie, @bvoight28, @bpasaniuc and everyone else. More exciting work to come!