MITO-GARAGE

MITO-GARAGE project news, which aims to understand the
functional role of key parts of the powerhouse of the cell, the mitochondrion. Look for error and fix it.

[MITO-GARAGE @MITO_GARAGE]

Very interesting publication:
Mitochondria directly interact with the nuclear pore complex'
https://t.co/eqrTpLrFPc

[MITO-GARAGE @MITO_GARAGE]

Yesterday marked the end of an amazing Euromit2026 in Angers!
As expected, it was a tremendous event, bringing together outstanding research, inspiring discussions, and the opportunity to reconnect with colleagues and friends from the mitochondrial community.

[MITO-GARAGE @MITO_GARAGE]

Butyrate extends health and lifespan in mice with mitochondrial deficiency

https://t.co/eQFChIRbB0

[MITO-GARAGE @MITO_GARAGE]

Mitochondrial NAD kinase Pos5 is required for CoQ biosynthesis in yeasts https://t.co/CtqtkzOgqA

[MITO-GARAGE @MITO_GARAGE]

Transplantation of encapsulated mitochondria alleviates dysfunction in mitochondrial and Parkinson’s disease models: Cell https://t.co/siKs6PEFDX

[MITO-GARAGE @MITO_GARAGE]

Attending the presentation of the SuperDani project! To raise awareness and support for Mitchell Syndrome and its research, led in Granada by my colleague Pablo Ranea Robles!

Things that truly matter!

[MITO-GARAGE @MITO_GARAGE]

Amazing preclinical rationale and 1st-in-human use of 4-hydroxybenzoic acid (4-HBA) as a targeted metabolic approach for COQ2-related primary coenzyme Q10 deficiency, with rapid renal improvement and clinical gains in a child with a Leigh-like phenotype.
https://t.co/ZYv2wWjn64

[MITO-GARAGE @MITO_GARAGE]

N‐Acetylglucosamine Selectively Attenuates Neuroinflammation in a Mouse Model of Mitochondrial Dysfunction, Amazing work from my colleague Laura Jimenez from MitoLab-UGR. https://t.co/e8dj3KTOF2

[MITO-GARAGE @MITO_GARAGE]

Hace unos días se publicó la resolución de las subvenciones concedidas por la Junta de Andalucía. Muy orgulloso de que nuestra propuesta haya sido seleccionada. Seguiremos avanzando en el conocimiento de las enfermedades raras su tratamiento https://t.co/kNSXpiDZkM

[MITO-GARAGE @MITO_GARAGE]

A few days ago, I received this awesome mug and this super cool plush toy, a reminder that what we do matters. Thank you so much to the patients and their family for their resilience and strength. Keep up the great work, and Happy Christmas!

[MITO-GARAGE @MITO_GARAGE]

Uridine-sensitized screening identifies demethoxy-coenzyme Q and NUDT5 as regulators of nucleotide synthesis
https://t.co/mEqg37878W

[MITO-GARAGE @MITO_GARAGE]

Ribonucleotide incorporation into mitochondrial DNA drives inflammation
https://t.co/e3v2vOEKsI

[MitoAction @MitoAction]

On Saturday 20 September, landmarks will glow green for #MitochondrialDisease.

Join in from home—light up in green, invite others, and share photos.

Every light counts.

https://t.co/Hw7HxQkVPE

#LightUpForMito #WorldMitoWeek2025 #DecodeTheMitoPuzzle

[AEPMI @AEPMI]

💡El 20 de septiembre se iluminarán de verde 💚monumentos de todo el mundo por las Enfermedades Mitocondriales , únete!! ya tenemos las primeras confirmaciones desde España👉 https://t.co/nWRu8rjp8E #LightupforMito

[MITO-GARAGE @MITO_GARAGE]

Spectacular results of the 4-HB on COQ2 deficiency in a very young patient with Leigh-like lesions. Great work from the MITOLAB Granada and Collaborators

[Luis Carlos López @luiscaloga]

Thrilled to share our Brain paper: a rational therapy for primary CoQ deficiency: from a UGR COQ2 mouse model to a 3-year-old with SRNS + Leigh-like lesions. Outcome: complete renal remission + clear neuro gains within 6 months. @AgEInves @OTRIUGR
https://t.co/xuXV8B4ene

[Universidad Granada @CanalUGR]

La #UGR en la lucha contra las enfermedades raras 💚

👨‍🔬 Investigadores de la UGR han liderado un estudio pionero que abre una nueva vía para tratar la deficiencia primaria de coenzima Q, una enfermedad mitocondrial rara y grave

ℹ️ https://t.co/2PRxxKej1c

[MITO-GARAGE @MITO_GARAGE]

Very interesting work of our colleagues in the Mitolab in the University of Granada! Proving that the β-Resorcylic acid is a powerful tool to treat MASLD and obesity also in genetic models! https://t.co/rmZtKVS5W3

[MITO-GARAGE @MITO_GARAGE]

Striking results recovering HPDL1 deficient patient and mouse model using Coenzyme Q headgroup intermediate 4-HB!
https://t.co/Nsdiug4A5c

[MITO-GARAGE @MITO_GARAGE]

Amazing work from our colleagues in the MitoLab UGR! The combination of CoQ10 and vanillic acid completely recovered the fatal encephalopathic phenotype of CoQ defficient mouse model! Great news for the CoQ community #mitochondria #RareDiseases

[Luis Carlos López @luiscaloga]

New study in @CommsMedicine : combining CoQ10 + vanillic acid shows synergistic therapeutic effects in a model of primary CoQ deficiency.
Multi-targeted strategies may transform treatment for mitochondrial disease.
👉 https://t.co/RmQYToxrjh
#Mitochondria #TranslationalResearch

[MITO-GARAGE @MITO_GARAGE]

Systematic profiling reveals betaine as an exercise mimetic for geroprotection: Cell https://t.co/VIHw12jfXz