Looking forward to joining Dr. Jiwon Oh at a @PeerView live symposium during #CMSC2026 on advancing care in #MultipleSclerosis, including the role of #BTKi. Join us 5/27 at 5 PM EDT in Charlotte or virtually: https://t.co/BBUxP9r81r
#Neurology#MedEd
Excited to see our work published in @GreenJournal group! We show that cladribine profoundly reshapes the CSF cell landscape in MS, providing new insights into treatment effects within the CNS. Thanks to all, especially @MS_ResearchDoc and Roman Smirnov! https://t.co/1VnWbqfTet
New Pathways, New Possibilities in #MultipleSclerosis: Enhance your ability to interpret clinical data to identify ideal candidates for #BTKi therapy with Drs. Jiwon Oh and Gregory F. Wu (@MS_ResearchDoc), 5/27 at 5:00 PM EDT: https://t.co/jrh2KxXrWR #CMSC2026#neurology
Overjoyed to share our new work exploring the antigen specificity of CSF-expanded CD8+ T cells in #multiplesclerosis#EBV in @natimmunol 🧵1/
https://t.co/CSkBPLFO09
🚨 Paradigm shift in #MultipleSclerosis 🚨
New study in Nature Medicine shows MS is not fixed subtypes but a dynamic continuum of states across 4 dimensions: disability, brain damage, relapses & silent inflammation.
📖 Read: https://t.co/MYvAAI6AiV
#MS#Neurology#AI
CSF cell analysis is key to understanding neurological diseases but has been limited by cell fragility. Millet Wallisky et al. introduce a rapid, one-step method for efficient CSF immune profiling
Check out the paper below 👇
https://t.co/loCOZF1gVX
Pleased to write this editorial with Larry Steinman about a potential novel antibody in MS
https://t.co/pSkJlvM9OU
Original manuscript here:
https://t.co/LzndcCZ6SA
1/ I am thrilled to share our latest paper: A single-cell compendium of human cerebrospinal fluid identifies disease-associated immune cell populations, @jclinicalinvest! Thanks to @MS_ResearchDoc, @BrianEdelson2, @maxim_artyomov, and co-author Roma for this collaborative effort!
@mzhlab I am proud to share our manuscript published in @ANA_journals today. 🥳https://t.co/Ho4jcUhqhv
We used data-driven approaches to analyze paired #CSF and blood #FlowCytometry of 8,790 (discovery) + 3,201 (validation) patients.
A #tweetorial 🧵1/16
Exciting news! Our new paper is published at Annals of Neurology!
Check it out to see how large-scale CSF and blood flow cytometry can reveal disease clusters to improve diagnosis and understanding
https://t.co/JzIIUSuKVn
Using sc-RNA-Seq to delineate T cell changes in AD, demonstrates an up regulation of exhaustion markers in CD8+ T RM cells within 5xFAD mouse brain.
Check the link below 👇
https://t.co/64Zjm72BSj
I'm excited to announce that Jennifer Lawrence's thesis work is now out! Check it out here:
JCI Insight - Microglia drive diurnal variation in susceptibility to inflammatory blood-brain barrier breakdown https://t.co/0qVgKm8W86
Post-mortem MS brain display PD1+ Granzyme B+ tissue-resident memory (Trm) T cells in MS lesions, in contact with EBV infected B cells promoting local CNS inflammation.
Check out👇 this 2023 interesting study from @FrancescaAloisi
https://t.co/1TfrE0xwiG
@MS_ResearchDoc@KateSadlerPhD Another super important TRP paper that I just came across because of a new paper on how fever impacts CD4 T cell responses by @DarrenHeintzman.
Linking the TRPV paper here to add it to this thread:
https://t.co/cRlW1sNuk4
Excessive and repetitive Ampicillin treatment alter the gut-brain axis. Ampicillin induce neuroinflammation through NfL, NOS2 and GFP release.
Check out 👇 the work by @TouilBoukoffa team.
https://t.co/aB17x8K8fY
Incredibly excited to share our latest work exploring the antigen specificity of clonally-expanded CSF-enriched CD8+ T cells in MS #multiplesclerosis#Tcells#EBV 🧵1/
https://t.co/8modGjmFBY