Mircea Andrei-Alexandru

Carol Davila University of Medicine
Universite De Paris - Medecine

[NextGen Pathology Group @PathologyGroup]

Article by @AlexandraChera and Antoanela Tanca published in @DiscoveriesJ is now on #PubMed Central. Congratulations!

[NextGen Pathology Group @PathologyGroup]

Monkeypox, a current global health issue: brief review on prevention and treatment
https://t.co/AChnpi5uUe

@stillapeanut @anamaria15920 #VictorBabesInstitute #UMFCD #CarolDavilaUniversity #UMFCarolDavila

[NextGen Pathology Group @PathologyGroup]

Cancer detection during surgery: FDA-approved use of pafolacianine
@mihaeladindere @obucur1 #VictorBabesInstitute #UMFCD #CarolDavilaUniversity #UMFCarolDavila
#pafolacianine #FDA #cancerdetection
https://t.co/8mDz7ceeCQ

[Octavian Bucur @obucur1]

Congratulations Andra Fortner and Alexandra Chera for their manuscript just published in @FrontCellDevBiol, IF 6!
@andra314159 @AlexandraChera @AntoanelaTanca #Apoptosis #CSK #celldevbio
#VictorBabesInstitute #VironMMI #VironInstitute

[NextGen Pathology Group @PathologyGroup]

Original study: Endogenous Modulation of Extracellular Matrix Collagen during Scar Formation after #Myocardial #Infarction https://t.co/qAhqTccjyp

@dav_schumacher @ElisaLiehn @mihaelarusu @obucur1
@IJMS_MDPI #CardioTwitter #collagen #scar #extracellular

[Mircea Andrei-Alexandru @M_AlexAndrei]

As of 2017, NIH's deep learning system matching semantic labels (i.e.: diagnoses) to images had a top-one & top-five accuracy of 61-66% & 93-95%.

[Mircea Andrei-Alexandru @M_AlexAndrei]

How is a convoluted neural network classifying radiology images assessed ?
1. Accuracy = Corrected predicted samples/All predictions
2. Top-five accuracy (assessing if the correct label pertains to the five highest predicted classes)
3. Confusion matrix - predicted v. true labels

[Mircea Andrei-Alexandru @M_AlexAndrei]

The cloud alternatives (e.g.: Microsoft Azure, Google Cloud platform) are advantageous for reducing the training time for large datasets.

[Mircea Andrei-Alexandru @M_AlexAndrei]

Employing CPUs vs. GPUs for deep learning in radiology

CPUs
- Large memory size
- Used for sequential processing
- Restricted memory bandwidth

GPUs
- Limited memory size
- Used for parallel processing
- High bandwidth

GPUs are preferred over CPUs.

[Mircea Andrei-Alexandru @M_AlexAndrei]

4. Monitoring (i.e.: longitudinally determine regression or stagnation of lesions on imaging, reocurrence of arrhythmias such as non-sustained VT)
5. Prognosis (e.g.: overall survival in cancer patients; burden and arrhythmia-free interval)

[Mircea Andrei-Alexandru @M_AlexAndrei]

Deep learning and its healthcare applications

The AI tasks used in healthcare are:
1. Preprocessing (e.g.: artifact reduction on CT scans/EKGs)
2. Detection (boxing lesions on imaging, pattern recognition of arrhythmias)
3. Classification (binary - benign/malignant; multiclass)

[NextGen Pathology Group @PathologyGroup]

Intraoperative Tumor Detection Using Pafolacianine
https://t.co/1E29D09SAe #mdpiijms via @IJMS_MDPI

@mihaeladindere @AntoanelaTanca @ElisaLiehn @obucur1
#VictorBabesInstitute @RWTH @SyddanskUni #UMFCD #UMFCarolDavila #VironMMI #VironInstitute
#cancer #pafolacianine #surgery

[Octavian Bucur @obucur1]

Our review by Alexandra Chera et al. titled "Thyroid-related adverse events induced by immune checkpoint inhibitors" was just published in @FrontiersEndocrinol, IF 6.
#thyroid #immune #checkpoint #checkpointinhibitors
#VictorBabesInstitute #VironMMI #VironInstitute

[NextGen Pathology Group @PathologyGroup]

Promising Therapies for Atrial Fibrillation and Ventricular Tachycardia https://t.co/WTo1hHvxD7 #mdpiijms via @IJMS_MDPI @MDPI
@M_AlexAndrei @ElisaLiehn @obucur1
#VictorBabesInstitute @RWTH @SyddanskUni #UMFCD #UMFCarolDavila #VironMMI #VironInstitute #Cardiology #CardioTwitter

[Octavian Bucur @obucur1]

Our review by @M_AlexAndrei et al. titled "Promising Therapies for Atrial Fibrillation and Ventricular Tachycardia" was just published in @IJMS_MDPI, IF 6.2.
https://t.co/dRS47yXgnD

#heart #atrialfibrillation #tachycardia

[Discoveries @DiscoveriesJ]

Remdesivir: the first FDA-approved anti-COVID-19 Treatment for Young Children https://t.co/6Z84kN8I9q

@AlexandraChera #VictorBabesInstitute #UMFCD #UMFCarolDavila
#Covid_19 #SARSCoV2 #FDA #children #remdesivir

[Frontiers - Endocrinology @FrontEndocrinol]

New Research: Thyroid-related adverse events induced by immune checkpoint inhibitors: Immune checkpoint inhibitors, namely anti-CTLA-4, anti-PD-1 and anti-PD-L1 monoclonal antibodies, have emerged in the last decade as a novel form… https://t.co/Mskq56ezlx #Endocrinology #Endo