Mahmoud Diab

Senior Cardiac Surgery Consultant, Department of Cardiothoracic Surgery, Jena University Hospital, Germany

[Tulio Caldonazo @TulioCaldonazo]

Glad to share new findings on behalf of REMOVE Trial Investigators

✅ Best oral presentation at EACTS 2023 (🎙️@HrisKirov)
✅ EJCTS Publication

‼️Hemoadsorption use in patients with S.aureus IE was not associated with ⬇️ organ dysfunction or mortality

🔗https://t.co/J8x6nHh1fQ

[Tulio Caldonazo @TulioCaldonazo]

🆕Check out our new study published in @JAHA_AHA

‼️Patients with IE and formal indication for surgical intervention who underwent surgery are associated with a lower risk of short- and long-term mortality when compared with conservative treatment.

🔗See: https://t.co/Diyf0PSHum

[Mahmoud Diab @MahmDiab]

@luca_koechlin @HrisKirov @ToDoenst @TulioCaldonazo @PCSchulzeMD @alexmoschovasmd @FaerberGloria Thank you Dr. Köchin for the question. The REMOVE study was conducted in 14 cardia surgery Centers. Measurements of high sensitivity Troponin was done according to the available Troponin assays in each Centers. Therefore, either Troponin I or T was used.

[JACC Journals @JACCJournals]

Results of this #JACCAdvances meta-analysis suggest antithrombotic therapy in infective endocarditis patients was not associated with a higher frequency of cerebrovascular events or intracranial hemorrhage. Learn more: https://t.co/oN7ejAYrzS

[Hristo Kirov @HrisKirov]

Teamwork is the secret that makes common people achieve uncommon results!

Happy to become the EACTS award for best e-poster in the cardiac field and thanks to @ToDoenst @TulioCaldonazo @MahmDiab @FaerberGloria for being the best team one can join!

@EACTS @uniklinik_jena

[Payam Akhyari @AkhyariMD]

@TulioCaldonazo @ToDoenst @HrisKirov @DVervoort94 @M_Pompeu_Sa_MD @MMarinCuartas @pomyers @JJahanyarMDPhD @LATAM_LACES @RMSSAA @VictorDayan1 Keep up the spirit!
🫀🙌✊️

[Mahmoud Diab @MahmDiab]

Outcomes of Concomitant Coronary Artery Bypass Grafting in Patients With Infective Endocarditis: A Systematic Review and Meta-Analysis - ScienceDirect https://t.co/pIXokpRrvT

[Hristo Kirov @HrisKirov]

Does the Use of Anticoagulation or Antiplatelet
Therapy Increase Cerebrovascular Events in Patients with Infective Endocarditis? Presented by @MahmDiab #ESC2023
@ODzemali (chairperson)
Find a summary ⬇️

[Tulio Caldonazo @TulioCaldonazo]

➡️ In endocarditis patients, adding CABG to valve surgery do not affect perioperative or long-term mortality. Additionally, concomitant CABG may be associated with higher postoperative stroke.

#STSCoronaryConf2023
@MahmDiab @ToDoenst @HrisKirov

[Tulio Caldonazo @TulioCaldonazo]

🔥Hot off the press🔥
We summarized all available evidence on the cardiac surgery field provided in 2022.
Check out the new contributions about the treatment of coronary artery disease, aortic surgery, valve disease and terminal HF.
See more: https://t.co/nLJgDqGG9m

[Torsten Doenst @ToDoenst]

Immortal Time Bias: the hidden confounder in assessing cardiosurgical treatment effects | European Heart Journal | Oxford Academic #heart surgery, ⁦@echo_stepbystep⁩ ⁦@TulioCaldonazo⁩ ⁦⁦@HrisKirov⁩ https://t.co/GMIkRhpTAS

[Mahmoud Diab @MahmDiab]

@asmae_gassa @TulioCaldonazo @Mitrovalvology @ToDoenst @HrisKirov @M_Pompeu_Sa_MD @DVervoort94 @MMarinCuartas @TasoudisPanos @JefVandenEynde @JJahanyarMDPhD @hagel_stefan Thank you Asmaa

[Mahmoud Diab @MahmDiab]

@TulioCaldonazo @Mitrovalvology @ToDoenst @HrisKirov @M_Pompeu_Sa_MD @DVervoort94 @MMarinCuartas @TasoudisPanos @JefVandenEynde @JJahanyarMDPhD @hagel_stefan Thank you Tulio

[Mahmoud Diab @MahmDiab]

@drraycleemd @samsaid75 @Kareem_Bedeir @JJahanyarMDPhD @HrisKirov @ToDoenst @TulioCaldonazo @RakanINazer @DrZeigler1 @AortaSurg We noticed that the sensitivity of TEE to detect abscess is poor. We noticed that combining pre operative Tropenin und TEE together increases the predictability of abscess dramatically. We are going to present this in the upcoming ESC congress.

[Mahmoud Diab @MahmDiab]

@JJahanyarMDPhD @samsaid75 @HrisKirov @ToDoenst @TulioCaldonazo @RakanINazer @drraycleemd @DrZeigler1 @AortaSurg CT. If no Progression of ICH is detected we go for surgery. During surgery we try to keep the ACT just above 400 to start CPB. We prefer biological valves and we give prophylactic anticoagulation. We do another CT to check for progress postoperatively.

[Mahmoud Diab @MahmDiab]

@JJahanyarMDPhD @samsaid75 @HrisKirov @ToDoenst @TulioCaldonazo @RakanINazer @drraycleemd @DrZeigler1 @AortaSurg Yeas we developed an algorithm for patients wir ICH in our center. If the patient is hemodynamically stable, does not have high risk of embolization”no huge mobile vegetations, and does not have local progression like abscess we wait for a week and then we repeat the

[Mahmoud Diab @MahmDiab]

@samsaid75 @JJahanyarMDPhD @HrisKirov @ToDoenst @TulioCaldonazo @RakanINazer @drraycleemd @DrZeigler1 @AortaSurg But don’t forget that all such papers are biased”immortal time bias”. Patients who die waiting for surgery are not included in the analysis.

[Mahmoud Diab @MahmDiab]

@samsaid75 @JJahanyarMDPhD @HrisKirov @ToDoenst @TulioCaldonazo @RakanINazer @drraycleemd @DrZeigler1 @AortaSurg Not just a neurologist, but a dedicated neurologist to the endocarditis team will help in decision making. We have 2 dedicated neurologists who revised, retrospectively over 500 cases of endocarditis and they gained an enormous experience regarding this issue.

[Mahmoud Diab @MahmDiab]

@LBaddour1 Thank you Dr. Baddour for tweeting this update.

[Mahmoud Diab @MahmDiab]

@LBaddour1 @MayoClinicINFD @MayoClinicCVS Thank you for the comment. We did subgroups-analyses including S. aureus IE as a subgroup compared to non-S. aureus IE. There was also no difference between hemoadsorption group and the control group.