Researchers from @MGHMedicine@CGM_MGH and colleagues find DNA-based score could enable early identification of Alzheimer’s risk, in a @PLOSGenetics study. https://t.co/TTEpsLdsYw"
Round of applause for the newest member of the EGD Hall of Fame:
1️⃣biopsied a lesion over a large varix. It was esophageal cancer
2️⃣banded the cancer/varix, curing cancer and treating the varix
https://t.co/yP6D1TRDc6 #cirrhosis#livertwitter
Why are so few clinical prediction models actually implemented in medical practice? This leaky model implementation pipeline summarizes some of the reasons
https://t.co/1oiHWsxllh
New from @ManishParanjpe and co. in @PLOSGenetics
Polygenic score for Alzheimer’s identifies individuals with worsened neurocog. trajectory
and, by studying healthy individuals in the tails of the PRS distribution, nominates new protein biomarkers
https://t.co/g5zTqc9KZB
Cool paper showing that in autosomal dominant disorders, it might be possible to compensate for the defective gene copy by amplifying the healthy gene copy by manipulating gene exp regulation (in this case, blocking miRNA binding) Fascinating !!
Excited to share our latest work investigating why Alzheimer's Disease is more common in women then men on the molecular level: https://t.co/QvfcRSzGzr - congrats @ManishParanjpe, Stella Belonwu, @KellyZalocusky, @tomiko22, @ParanjpeIshan, @BenGlicksberg and others!!!!
Gov. Mike DeWine of Ohio announced that the state would give five people $1 million each in return for having been vaccinated as part of a weekly lottery program. https://t.co/86FkotiMEi
Do mRNA vaccines prevent asymptomatic spread?
Heck, yes!
best study to date
N=23K, prospective cohort
Outcomes: symptomatic disease as well as surveillance testing with q2 week nasal swab/PCR test!!
Vaccine effectiveness: 86%, 7 days after 2nd dose
https://t.co/2PSqcpG2BE
There are many reasons that HAVEN failed, but one of them is that 'something-for-nothing' ideas that are popular with the punditry-- like prevention + wellness saving money or price transparency saving money-- have poor empirical support
#OPEC opens its meeting to discuss 2021 oil quotas, as Algerian minister and OPEC president urges the bloc to stay patient and stick to the cause through the downturn #OOTT
https://t.co/1puv3H8gX5