Marta Sans Escofet

Sr. Scientist - Spatial Biology Discovery at Merck | MDAnderson, UT Austin Alumni

[Marta Sans Escofet @Marta_Sans_]

So happy to have our study now out in @CD_AACR!! We used #SpatialTranscriptomics and COMET imaging to spatially profile IPMN lesions of the #pancreas and identified NKX6-2 as a previously unknown transcription factor driving indolent gastric differentiation.

[Elizabeth McKenna @ElizSMcKenna]

Now online in @CD_AACR: #SpatialTranscriptomics of Intraductal Papillary Mucinous Neoplasms (#IPMN) of the Pancreas Identifies NKX6-2 as a Driver of Gastric Differentiation and Indolent Biological Potential @Marta_Sans_ @Aiims1742 @MDAndersonNews https://t.co/BJBMFDkaSh

[Jennifer Guerriero, PhD @JennGuerriero]

PSA: Stop calling macrophages in tissue M1 or M2. These are not states that exist in biology. The only use of M1 is a macrophage cultured ex vivo with LPS and IFNg; and for M2: IL-4/13/10. Macrophages in tissues are highly complex and diverse and do not resemble either of the aforementioned M1/M2 states. M1/M2 language causes confusion and sets the field back. Refer to your macrophages by the molecules they express and the cytokines they make.

[Carles Puyol @Carles5puyol]

Orgullós d’aquest equip! Visca el Barça! 💙❤️

[Eberlin Lab @EberlinLab]

We are thrilled to share our newest paper in @angew_chem!! 📢🚨 We combined DESI-MSI spatial metabolomics with spatial transcriptomics to unlock multi-omics insights in breast and lung cancer tissues 🧬🧫
Check it out here 👉 https://t.co/PdDPNl47Ek @BCMFromtheLabs @BCM_Surgery

[Anirban Maitra @Aiims1742]

New @Gut_BMJ paper from @MDAndersonNews illustrates a novel metabolic reprogramming observed in cystic precursors of #PancreaticCancer that upregulates long-chain hydroxylated sulfatides in the neoplastic epithelium.
@BallaroRiccardo @Marta_Sans_, led by Johannes Fahrmann

[Marta Sans Escofet @Marta_Sans_]

@Aiims1742 @IamLinghua @GuangshengPei @jiminmin_v @MDAndersonNews @Nature Amazing!! Excited to see this out! 👏🏻👏🏻👏🏻

[Linghua Wang, MD, PhD @IamLinghua]

Thrilled to share our latest study just out in @Nature 😄A major milestone in our collaboration with ⁦@Aiims1742⁩ Led by brilliant ⁦⁦⁦@GuangshengPei⁩ ⁦⁦⁦⁦⁦⁦⁦⁦⁦⁦⁦@jiminmin_v⁩ ⁦⁦@MDAndersonNews⁩ https://t.co/T9JFccxBPn

[Science News @SciencNews]

The immune response

[Marta Sans Escofet @Marta_Sans_]

Join us! We're offering an exciting postdoctoral position that focuses on integrating MALDI-MS imaging and Spatial Transcriptomics for drug discovery. If you're passionate about cutting-edge research in this field, we'd love to hear from you! https://t.co/JVlc9CDI2g

[Anirban Maitra @Aiims1742]

Our dinner tradition of current & former members of the Maitra Lab continues at #AACRPan24. It was wonderful to catch up with everyone.
Thank you @AACR @letswinpc for the two scholar in training awards. Exciting day of science for all of us in #PancreaticCancer research.

[Fredrik Thege @FredrikThege]

Very excited to share our latest manuscript looking at metaplastic reprogramming and glycolytic dependency in GNAS mutant IPMNs! @MDAndersonNews @Gut_BMJ

https://t.co/Yy4zj0boec

[Eric Topol @EricTopol]

Good critique of multi-cancer early detection tests, liquid biopsy @NatureMedicine editorial
https://t.co/ug1huwdCJP

[Anirban Maitra @Aiims1742]

In @CR_AACR
Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-specific Transcriptome & Molecular Subtype
https://t.co/c85AgTTvGp
The pipeline described here can be used in plasma samples for:
Transcriptomic subtyping
Fusion detection
Longitudinal monitoring to targeted therapies
More studies coming!

[Jeffrey E. Dick @Jeffrey_E_Dick]

We have lost a scientific giant, Prof. Allen J. Bard. Thank you, Al, for everything you taught us. You will be greatly missed. Rest in peace.

[Anirban Maitra @Aiims1742]

Congratulations @TaniguchiMD - I know how incredibly proud you are of this @TheLancetOncol study out today. Your paper made the cover highlight!
This was Cullen’s baby from the very preclinical inception in his lab, and it breaks my heart that I can’t shake his hand in person.
Stereotactic body radiotherapy with or without selective dismutase mimetic in #PancreaticCancer: an adaptive, randomised, double-blind, placebo-controlled, phase 1b/2 trial.
https://t.co/q4FmfjxCru
Cc: @ACKoongMDPhD @PrajnanDasMD @colbertle @aguilera_md @DrShubhamPant @Vince_BernPag @ebludmir @eugenekoay

[Anirban Maitra @Aiims1742]

Some joy at the end of a rough week. Congratulations to @VBahrambeigi for successfully defending his thesis yesterday. Vahid was co-mentored by @skopetz and developed the extracellular vesicle RNA (evRNA) sequencing pipeline in the lab.
Next stop - LGG fellowship!
@MDA_UTHGrad

[Marta Sans Escofet @Marta_Sans_]

@carogarciax2 I am so very sorry Caro, he was such a kind man and amazing mentor to so many 💔

[Anirban Maitra @Aiims1742]

It’s been 24 hours since I heard the news but it still feels unreal.
Goodbye my friend, the one and only Sensei Taniguchi. I am 💔 - most importantly for his young family, but also his wonderful mentees whom he cherished and his colleagues.
@TaniguchiMD rest in peace 🙏🏽

[Anirban Maitra @Aiims1742]

The Maitra Lab winding down the evening at #AACRPan23, and catching up with lab alumni @Marta_Sans_ & Maria (both at Merck, Boston).
Our team in Boston represented by:
🇺🇸 🇪🇸 🇮🇹 🇮🇳 🇰🇷 🇯🇵 🇸🇪 🇨🇴 🇪🇬
@FredrikThege @jiminmin_v @FraHeaven
Back to #PancreaticCancer research in the AM!

[Marta Sans Escofet @Marta_Sans_]

@Aiims1742 @FredrikThege @jiminmin_v @FraHeaven So good to see everyone! ☺️

[VHIO’s Cancer Genomics Lab @Genomicslab_]

📢 Just out in @CD_AACR. We describe for the 1st time #ctDNA in breast milk from BC patients! Unique example of reverse translation from hypothesis generated by @vallhebron @VHIO patient ! Amazing team effort led by @AnaVivancosVHIO and Cristina Saura👇 https://t.co/HcSPIBW7ey