Today I learned sepsis causes thrombocytopenia because bacteria express neuraminidase, a virulence factor that cleaves sialic acid from host cells allowing for greater adherence to cell surface. When platelets get desialylated they get cleared by kupfer cells in the liver.
2005: “It’s all crystalloids.”
2010: “No, 1:1:1 is the holy grail.”
2015: “TXA for everyone.”
2018: “Whole blood back to the future.”
2020: “It’s the endothelium!”
2023: “AI will solve resuscitation.”
2025: “Actually… it’s the platelets.”
Funny how the more we learn, the smaller the battlefield becomes
and all roads keep leading back to surgeon scientists who still practice clinical medicines
#Trauma
How can I make this more clear?
There is no war.
Palestine has no army.
Hamas wants to give back all the hostages.
Israel wants to murder every single Palestinian, half of which are children, almost 2 million ppl.
What's so hard to understand about that?
It's a genocide.
Creating a reading list so y'all can learn more about the extended colonial project that is Balochistan. You can find most books on https://t.co/IF1i6kGH6Y, https://t.co/EFWmwiLOGs or https://t.co/WS4AEFQRe4. Always be critically, understand, and contexualize. Happy Reading!
This photo shows some of the destruction in #Gaza due to the ongoing israeli aggression.
Photo taken by Roshdi, who was murdered a few hours ago in an israeli airstrike.
It's a privilege to be able to just exit an app and take a break from the horror. It's a privilege to be able to mute words and return to feeds full of mindless tweets and reels.But this is reality for over 2million ppl and the silence of the int. community will not be forgotten.
The original 1960 paper from Cattell and Braasch describing right medial visceral rotation (the Cattell-Braasch maneuver).
Though most commonly associated with operations for trauma, it was originally described for tumors.
The entire manuscript is 482 words long. 🧐
“So first you check serum osmolality to see if it is true hyponatremia, then you need to see if ADH is on or off by looking at the urine osmolality, and the urine sodium will next tell you the intravascular volume status.”