Megi Clarke

Neuroscientist 🧠👩🏽‍💻 I use MRI to study multiple sclerosis, improve its diagnosis and predict the future course of the disease ✨

[Megi Clarke @MegiClarke]

I’m so happy to share the results from our small but very exciting 7T study - my first paper as a senior author! 🤓 🧠 We explore the prevalence and dynamics of T1 dark rims in new and established lesions, including PRLs, and propose the origin of the dark signal on T1 MRI👇🏼

[Journal of Neuroimaging @JNeuroimaging]

T1‐Dark Rim as a Marker of New and Chronic Active Multiple Sclerosis Lesions: A Serial Study With Frequent 7T MRI
https://t.co/tgPKiqhHvf

#neuroimaging #neurology #neurorad #radres @WileyNeuro @asneuroimaging #multiplesclerosis #chronicactivelesions #7T #MRI

Free read

[MS Society UK @mssocietyuk]

Our MS Frontiers conference is the UK's largest biennial conference for MS research professionals. 🧡

Ahead of this year’s conference, we’re inviting researchers to submit their abstracts before the deadline of Wednesday 4 February.

Find out more: https://t.co/lNnDBCoRjK

[Megi Clarke @MegiClarke]

This initiative was created in response to the many colleagues who contacted us for advice and we hope it will make a real difference in clinical practice.

We welcome feedback and collaboration from the community. Please share this resource with colleagues who may benefit.

[Megi Clarke @MegiClarke]

🔬 New Resource for MS Diagnosis: Central Vein Sign Website https://t.co/HpkHdcgpmm

We are excited to announce a new website dedicated to supporting neurologists, radiologists, and radiographers in the use of the CVS as a diagnostic marker in suspected multiple sclerosis

[Megi Clarke @MegiClarke]

👉 What the website offers:

• Guidance on how you can easily access SWI sequences on all major MRI scanners (GE, Philips, Siemens)
• Step‑by‑step recommendations to simplify implementation
• A central hub for clinicians who have been asking how to obtain these sequences

[Megi Clarke @MegiClarke]

10 years ago, I attended my 1st ECTRIMS in Barcelona presenting results on the central vein sign in MS! A decade later, the CVS is in the new MS diagnostic criteria and our team just presented results of a new proposed diagnostic marker: T1-dark rims! Love to see the progress!💪🏼

[Pablo Naval-Baudin @pnavalbaudin]

1/ Very exciting work by @MegiClarke, M. Marshall, and team on the T1 dark rim on 7T! Congratulations!

https://t.co/m0YsKIAlqA

[Megi Clarke @MegiClarke]

@pnavalbaudin Great summary! Thanks for sharing! 😊

[Uni of Nottingham Press Office @UoNPressOffice]

An 8 minute MRI scan could replace painful spinal taps in diagnosing multiple sclerosis, a study led by @nikosevangelou3 @MedicineUoN @UoNFacultyMHS #MS #MultipleSclerosis

Read more @DailyMail ▶️https://t.co/zfTTFQ83jo

[IJMSC @IJMSCtweets]

J Neuroimag: "T1-dark #rims were more common than QSM rims, w/ greater prev in newly formed #lesions. We propose they represent edema & inflammation assoc w/ early stages of chronic active lesion formation visible despite, not bcse of, #iron accumulation." https://t.co/O9tTMpspQ0

[Megi Clarke @MegiClarke]

Can the central vein sign offer an alternative to lumbar punctures?#MS

Check out our latest results from a multi-centre, prospective study of 99 ppl presenting with typical CIS. We report not only sensitivity analyses but also discuss patient preferences.
https://t.co/h0kWwKorCF

[Dr. Brandon Beaber @Brandon_Beaber]

Incredible 7T MRI images in multiple sclerosis showing perivenular lesions with T1-dark rims on magnetization prepared 2 rapid gradient-echo https://t.co/GtgvarSxmY

[NEuRoMS @NEuRoMSproject]

The Spring 2025 issue of our Nottingham MS Research Group's newsletter is now available to read online. Discover more about some of our ongoing research studies in #MultipleSclerosis

🔗 https://t.co/ifQGchLmQR

[Megi Clarke @MegiClarke]

Proud to be presenting at #ABN2025 in Liverpool. We show that the NAIMS CVS assessment criteria are needed to maintain diagnostic performance of a simplified CVS rule (finding 6 CVS+ lesions). Finding more CVS+ lesions further increased specificity while maintaining sensitivity.

[Megi Clarke @MegiClarke]

@AtleeWitt @vuiis @VUmedicine @VanderbiltMSTP @ansleykunnath Congrats, Atlee!! 🥳 What an awesome achievement!!

[Barry Singer MD 🧠 @drbarrysinger]

Gilmartin: Optically pumped magnetoencephalography (OPM-MEG) is a non-invasive, wearable technology that images brain activity in real time. Delayed response on tasks like moving a finger to a prompt in people with #MS. #ACTRIMS

[Megi Clarke @MegiClarke]

Exciting opportunity for a postdoc with skills in neuroimaging and MS! I spent a year with this fantastic team in ☀️ Barcelona a few years ago and it was one of the highlights of my career so far! 🧠

[Alex Rovira @alexrovirarayos]

Postdoctoral Fellow (Neuroradiology) - VHIR https://t.co/azQg5jRnHP

[Megi Clarke @MegiClarke]

Many thanks to @ECTRIMS for organising a fantastic workshop on the upcoming revisions to the McDonald diagnostic criteria for MS! It’s amazing to see how years of accumulating research evidence is now going to change clinical practice across the world!

[Chris Gilmartin @ChrisGSG]

We want to improve how we diagnose people with MS! We're trying to avoid lumbar punctures. If you've been diagnosed with MS in the last 10 years, or know someone who has, get in touch! Let's improve care together! @BlancaDios @nikosevangelou3 @MegiClarke @chloechiengg