Michael Mina

MD,PhD. Immunology, Epidemiology, Infectious disease, CMO @invivyd @truviansciences, CSO @AnywhereDx, CEO HTR Advisors. Past: Harvard Faculty. Comments my own

[Michael Mina @michaelmina_lab]

With all the news of vaccines & immunity, did you know measles infections destroy immunity and cause “Immune Amnesia”, increasing risk of all other infections

Our research in ‘15 & ‘19 discovered this & the abbreviated story is written up nicely here:

1/
https://t.co/t5DKoQljxM

[Michael Mina @michaelmina_lab]

I'll be speaking @Nature's Meeting the Challenge of Infectious Diseases in a Changing World

To discuss with colleagues from around the world recent advances and challenges in infectious diseaes emergence, diagnostics, surveillance, and preparedness. https://t.co/A6dIxLiHkM

[Bill Gurley @bgurley]

Who out there has any data on the Amazon, JP Morgan, Berkshire effort that was eventually closed? I would love to learn what they learned. Email healthcare (at) https://t.co/g16RAYZoo9. Thx.

[Nolla Health @getnolla]

Skin conditions like acne and hyperpigmentation are dynamic and treatment-dependent.

Nolla Skin provides continuous monitoring of skin changes, enabling clinicians to better understand treatment response and refine care plans over time.

We believe in care built around progression, not a single visit.

#NollaHealth #Skincare #SkinHealth

[Michael Mina @michaelmina_lab]

@ENirenberg Love this question. I’ve been asking and attempting to answer it for years

[Anywhere Dx @AnywhereDx]

Anywhere DX has officially launched its campaign publicly on WeFunder. Hear from @michaelmina_lab about the context behind our mission and visit https://t.co/C22LPvfJoN to learn what all the buzz is about.

[Invivyd @Invivyd]

We've announced completion of enrollment in phase 3 LIBERTY trial evaluating VYD2311 antibody versus mRNA COVID-19 vaccine
Read full release here: https://t.co/mrROjs5HVq

[Nolla Health @getnolla]

AI has the power to democratize quality care. @michaelmina_lab with his vision of the future.

[Michael Mina @michaelmina_lab]

I’m not too sure that I can agree with their conclusions. Though have to give more thought.

For example, is it a lack of strong imprinting that creates vulnerabilities (one might more aptly call that a lack of useful cross reactive but protective antibodies) or…

Is it that the young children were adversely imprinted (in its usual framework) by later omicron variants as their first exposures. This imprinting is challenging them to be able to appropriately address a new saltation variant that is more akin to an older lineage of viruses.

To me, an omicron immune imprinting of the kids that creates a relative barrier hindering a proper response against BA.3.2 is the more parsimonious explanation. And fits expectations a bit more clearly.

[Michael Mina @michaelmina_lab]

Medicine and how each one of us interacts with our medical care is changing at a pace that is extremely difficult to comprehend.

5 years from now, primary care and many specialized care models are going to look nothing like they have in the past decades.

Nolla Health @getnolla is building a new generation of foundational models capable of diagnosing disease (and prescribing treatment) and maintaining health using the same types of multifaceted evidence (history, images, video, symptoms, labs…) that doctors use today.

Soon, everyone is going to have ready access to aspects of the best of what medicine and public health have to offer. Harnessed in the right hands, the potential benefits are a leap forward from anything we’ve ever seem.

[Anywhere Dx @AnywhereDx]

As we were building anticipation for a major announcement, more investors joined the party. Another $5K raised last night. More to come. Follow us on WeFunder to be the first to know when the news hits!

https://t.co/4a4p1rwzPS

[Michael Mina @michaelmina_lab]

Depends on the model, the company, and how the data is being used. Very similar to my superiors data concerns about how our medical data is sold today from our hospital systems!

In the case of Nolla, thr data stays private. The models are not leveraging the big LLM companies and are running locally. The systems are HIPAA compliant and the data doesn’t leave except when connecting to a real doctor- then with permission, the relevant info is packaged up passed to the doc.

[Michael Mina @michaelmina_lab]

Medicine and how each one of us interacts with our medical care is changing at a pace that is extremely difficult to comprehend.

5 years from now, primary care and many specialized care models are going to look nothing like they have in the past decades.

Nolla Health @getnolla is building a new generation of foundational models capable of diagnosing disease (and prescribing treatment) and maintaining health using the same types of multifaceted evidence (history, images, video, symptoms, labs…) that doctors use today.

Soon, everyone is going to have ready access to aspects of the best of what medicine and public health have to offer. Harnessed in the right hands, the potential benefits are a leap forward from anything we’ve ever seem.

[Nolla Health @getnolla]

AI has the power to democratize quality care. @michaelmina_lab with his vision of the future.

[PwME 4 bioMEdical research @ValeBodi]

Sadly the findings of @michaelmina_lab’s et al. on how measles’ infections destroy immunity and cause “Immune Amnesia” should be widely known and infections prevented with childhood vaccination: https://t.co/XbbVW3cXee
#Measles

[Anywhere Dx @AnywhereDx]

Big news incoming.

A milestone worth celebrating. An announcement worth sharing.

More soon. 👀

@michaelmina_lab

[Diana Berrent Nadia @dianaberrent]

👀👀👀

[Anywhere Dx @AnywhereDx]

We have all been there. A place we don’t know, paralyzed by an inability to know what’s going on or how to feel better. Do you have a recent story like this? We’d love to hear it.

[Michael Mina @michaelmina_lab]

Really interesting data. Not sure it’s a tropism change per se. But rather may be more a reflection of accrued immunity and antigenic imprinting. The virus is now 6.5 years old. The younger kids didn’t see the original strains - nor did they get the original vaccines. The development of immunity may well be shaping this more than a tropism change.

[Michael Mina @michaelmina_lab]

This is very cool. Great work @AndrewDudum for building an ecosystem towards actual *health* care

[andrewdudum @AndrewDudum]

The best consumer companies of the last decade don’t just provide a product. They provide an experience that can be tailored to how you want to live your life.

That’s the vision at Hims & Hers: not just a solution for a single condition, but an entire health ecosystem that gets you healthy, keeps you healthy, and adapts to the way your health evolves over time, both on and off the platform. We're making it easier and more affordable to sleep better, eat better, move better, and recover better.

That’s why we’re building Hims & Hers Member Benefits and adding more value over time. Very grateful to these brands, who believe in this vision and want to be a part of making it real for our millions of customers.

Once you get started, tag me and let me know how you’re stacking your benefits!

https://t.co/UbOmZXHhKg

[Michael Mina @michaelmina_lab]

FDA through and through. CDC and essentially all others deferred essentially all public health approaches re tests to a small group of highly conflicted people within FDA, the leader (Tim Stenzel) who was massively conflicted and failed to recuse himself - meanwhile prioritized only the company he used to help lead and kept essentially all others locked away