Michelle Zeller

[Menaka Pai, MSc MD FRCPC @MPaiMD]

Happy Wednesday! Late post - still in hospital! But here’s some more trustworthy DIY research around #COVID vaccines in kids 5-11. Today we talk about fertility. Does vaccination lead to infertility? 1/n

[Menaka Pai, MSc MD FRCPC @MPaiMD]

But we do know that COVID infection causes all kinds of inflammatory problems that COULD impact fertility. And it leads to erectile dysfunction! And it is particularly lethal in pregnant patients! And may even cause fetal harm! 16/n https://t.co/uR8Bd523CO

[Menaka Pai, MSc MD FRCPC @MPaiMD]

To sum up: there is NO evidence and NO physiologic basis for vaccines interfering with fertility. The myths are based on bad science & outright falsehoods. Billions of doses in, there is NO signal linking COVID vaccines & infertility. 15/n

[CONCOR-1 Trial @CONCOR1Trial]

Results of the @CONCOR1Trial have been published in @NatureMedicine (https://t.co/Fjqc0P5mib). A summary of the trial findings is available on our website: https://t.co/1tePfAzZg4

[CONCOR-1 Trial @CONCOR1Trial]

The @CONCOR1Trial found that #convalescentplasma did not reduce the risk of intubation or death in patients hospitalized for #COVID19 compared to patients who received standard of care

[CONCOR-1 Trial @CONCOR1Trial]

The @CONCOR1Trial found that #convalescentplasma units with an unfavourable antibody profile (including measures of both antibody quantity and function against SARS-CoV-2) were associated with a higher risk of intubation or death in hospitalized patients with #COVID19

[CONCOR-1 Trial @CONCOR1Trial]

THANK YOU to all involved in @CONCOR1Trial - patients & family members, plasma donors, research teams, Blood Banks, study investigators, Community Advisory Committee, blood suppliers, & funders. Much knowledge has been gained & further research opportunities borne of this trial.

[Menaka Pai, MSc MD FRCPC @MPaiMD]

The best way to see ourselves through this havoc remains the vaccine. The best way to prevent clots remains the vaccine. I trust our country’s health approval and surveillance process. I trust it to guide me, and guide people I care about (my patients and loved ones). 10/n

[Menaka Pai, MSc MD FRCPC @MPaiMD]

These rare, serious clots are concerning. BUT if you’re eligible for AZ vax? Our province is saying you’re at risk for COVID-19. So that ultra rare risk is outweighed by the real & common risks of COVID-19… an illness that itself gives you a >1 in 100 risk of blood clots. 8/n

[Menaka Pai, MSc MD FRCPC @MPaiMD]

2) Getting AZ vax reduces your risk, overall, of dying or hospitalization; 3) Our vaccine safety & surveillance system is SOLID. It picked up ~40 unusual serious clots (out of 20,000,000+ doses), some associated with low platelets [sticky cells that help your blood clot]. 7/n

[Menaka Pai, MSc MD FRCPC @MPaiMD]

They’re worried about the risk of clots with AZ vaccine. Let’s use that awesome human instinct (caution) and look at the data. Here’s what we know, now: 1) AZ vax doesn’t increase the risk of blood clots beyond the general population signal; 6/n

[Menaka Pai, MSc MD FRCPC @MPaiMD]

Yesterday @GovCanHealth, @MHRAgovuk, @EMA_News and my profession's organization @ThrombosisCan made clear statements that risks posed by AZ vaccine are far outweighed by its benefits. Does that square with media reports? Should we really get the first shot available to us? 2/n

[Menaka Pai, MSc MD FRCPC @MPaiMD]

We must work with you to talk about risks, benefits, fears, hopes, and strategies to keep you safe & in tune with your body. We'll do that together. Take the first vaccine that is offered to you, and we will get through this together too. 12/n

[CONCOR-1 Trial @CONCOR1Trial]

On the recommendation of the Data Safety Monitoring Committee, the @CONCOR1Trial has stopped enrolment. Trial update available on our website: https://t.co/1tePfAzZg4

[CONCOR-1 Trial @CONCOR1Trial]

Thank you to the thousands of individuals involved in @CONCOR1Trial who helped to advance our knowledge during a pandemic: patients and their family members, plasma donors, research teams, blood bank staff, study investigators, blood suppliers, and funders.

[Michelle Zeller @MickeyPZ1]

https://t.co/JSeADyqxBR

[CONCOR-1 Trial @CONCOR1Trial]

Plasma could be the key to help others recover from COVID.
If you, or someone you know, have fully recovered from #COVID19, you may be able to help others by donating plasma @CanadasLifeline.
Learn more and register to become a potential donor at https://t.co/VjCZBxLtyS.

[Menaka Pai, MSc MD FRCPC @MPaiMD]

Love this! In English and en Francais - @CanadasLifeline and @HemaQuebec are collecting convalescent plasma for #COVID19 trials across the country.

[Mark Crowther @crowthrm]

Odd Tweet for my account but if you have had #COVID19 your plasma is needed for treating others... consider donating once you are no longer infectious ! @CBCNews @jddneary

[Menaka Pai, MSc MD FRCPC @MPaiMD]

Have you had #COVID? @CanadasLifeline urgently needs your convalescent plasma for @CONCOR1Trial. https://t.co/fGNqIyVXw4