Mariam Museridze

PhD student from @LMU_Muenchen and @UniBonn. Studying structure and evolution of enhancers in fruit flies

[Michael 英泉 Eisen @mbeisen]

So it’s going to spend 3 years crippled by insecurity, messing up everything it tries, contemplate quitting as it’s friends get rich and start families, before finally pulling it all together in a manic amphetamine fueled two month stretch and making an amazing discovery nobody reads because it’s paywalled?

[Mariam Museridze @Mmuse19]

Very excited to finally share our latest paper! 🧬🪰
https://t.co/uwUI0ng8MS

[Nature Biotechnology @NatureBiotech]

An AI model generates thousands of synthetic CREs with programmed functionality. The CREs drive cell-type-specific expression in cell lines and show specificity in vivo. https://t.co/Sb28gLgMcs #NBThighlight

[Neil Renic @NC_Renic]

Academia is held together by caffeine, free labour, and the two people who nod encouragingly during presentations

[Mariam Museridze @Mmuse19]

@GilbertoAlva_Ca Thanks! I'll be presenting on the 26th and Conrad will be presenting his poster tomorrow 😊

[Mariam Museridze @Mmuse19]

I’ll be presenting this project as a poster at the upcoming #EMBL #Transcription and #Chromatin conference. Come check it out!

[Mariam Museridze @Mmuse19]

So excited to share our new preprint! 🎉
In this project, we're revisiting enhancer modularity with quantitative approaches in Drosophila 🪰🧬

Summary in the thread below. ⬇️
https://t.co/s0uIGr7MYR

[Mariam Museridze @Mmuse19]

These results pose the question of how functional modularity is achieved 🧬

[Mariam Museridze @Mmuse19]

So excited to share our new preprint! 🎉
In this project, we're revisiting enhancer modularity with quantitative approaches in Drosophila 🪰🧬

Summary in the thread below. ⬇️
https://t.co/s0uIGr7MYR

[Mariam Museridze @Mmuse19]

Our main conclusions are:
• Enhancers are much bigger than previously thought and extensively overlap.
• The body enhancer comprises at least 3 activities.
• Distribution of regulatory information is not even.
• Enhancers show different levels of functional modularity.