Molecules and Cells

Molecules and Cells is an international on-line open-access journal.

[Molecules and Cells @MolCells]

Molecules and Cells (2024 Impact Factor 6.5), the official open-access SCIE journal of KSMCB (Korean Society for Molecular and Cellular Biology) in collaboration with Elsevier, publishes exciting discoveries across all areas of biology.

[Molecules and Cells @MolCells]

Deficient chaperone-mediated autophagy in macrophages aggravates colitis and colitis-associated tumorigenesis in mice

https://t.co/kS4lwdeHKv

#Angiogenesis #Chaperone-mediatedAutophagy #ColorectalcancerHypoxia-inducibleFactor1Alpha #Tumor-associatedMacrophages

[Molecules and Cells @MolCells]

Ionotropic receptors mediate arachidic acid perception and food avoidance behavior in Drosophila melanogaster

https://t.co/CbPGC1z3GK

#ArachidicAcid #Drosophila #GustatoryReceptorNeurons #IonotropicReceptors #Taste

[Molecules and Cells @MolCells]

Egr2-dependent Mo-DCs regulate immunosuppressive NK cells, promoting neutrophil-mediated protective immunity against acute Listeria infection
https://t.co/D37arFoHWA

#AcuteListeriaInfection #EarlyGrowthResponseGene-2 #Monocyte-derivedDendriticCells

[Molecules and Cells @MolCells]

Charge-dependent localization of Toll-like receptor 5 at the plasma membrane

https://t.co/7XsZ1F8s9y

PlasmaMembraneLocalization #Polybasic
Residues #Toll-likeReceptor5 #Toll-likeReceptor9 #UNC93B1

[Molecules and Cells @MolCells]

Identification of a Unique Subpopulation of Mucosal Fibroblasts in Colorectal Cancer with Tumor-Restraining Characteristics

https://t.co/C8qjMfY87o

#cancerAssociatedFibroblast #Tumor-restraining CAF #ADAMDEC1 #CXCL14 #singleCell #sequencing

[Molecules and Cells @MolCells]

Tumor-derived CD84 promotes growth of acute myeloid leukemia cells via regulating nonhomologous DNA end-joining pathway

https://t.co/5U1gPgioIa

#AcuteMyeloidLeukemia #CD84 #Leukemia-initiatingCells #NonhomologousEnd-joining

[Molecules and Cells @MolCells]

N-Terminal deleted isoforms of E3 ligase RNF220 are ubiquitously expressed and required for mouse muscle differentiation

https://t.co/YQwCmrrPiW

#Isoforms #MuscleDifferentiation #Neurodegeneration #RingFingerProtein220 #Variants

[Molecules and Cells @MolCells]

Dietary salt induces taste desensitization via receptor internalization in Drosophila in a sexually dimorphic manner

https://t.co/JsxH5Y3rBo

#Desensitization #Drosophila #Endocytosis #Salt #SexualDimorphism

[Molecules and Cells @MolCells]

Conformational flexibility of His200 enables catalytic activity in the T200H mutant of carbonic anhydrase II

https://t.co/DZcv1AR7yB

#Active-siteWaterDynamics #CarbonicAnhydrase #EnzymaticMechanismIntermediateState #Site-directedMutagenesis

[Molecules and Cells @MolCells]

MicroRNA-196a increases apoptosis in B cells through downregulation of FOXO1

https://t.co/froa5J9jIK

#Apoptosis #B-cellActivation #BCellLymphoma #FOXO1 #MicroRNA-196a-5p

[Molecules and Cells @MolCells]

Effects of heterozygous SMG1 mutations on nonsense-mediated mRNA decay in human pluripotent stem cell model

https://t.co/icMv2PBC1G

#CRISPR/Cas9 #Kinase #NeuralOrganoids #Nonsense-mediatedmRNADecayActivity #PrimeEditing

[Molecules and Cells @MolCells]

Cholesterol sulfate as a negative regulator of cellular cholesterol homeostasis

https://t.co/PoKQZwM668

#Cholesterol #CholesterolHomeostasis #CholesterolSulfate3-Hydroxy-3-methylglutaryl-CoAReductase #Low-densityLipoproteinReceptor

[Molecules and Cells @MolCells]

Phosphorylation of eIF2α suppresses the impairment of GSH/NADPH homeostasis and mitigates the activation of cell death pathways, including ferroptosis, during ER stress

https://t.co/VLtoTEo6ON

#ATF4 #EIF2αPhosphorylation #ERstress #Ferroptosis #Glutathione

[Molecules and Cells @MolCells]

Cryo-EM structures of mouse bestrophin 1 channel in closed and partially open conformations

https://t.co/399eHDbBgO

#Bestrophin1 #Calcium-activatedChlorideChannel #GatingIonPermeation #StructureFunction

[Molecules and Cells @MolCells]

Protein-O-fucosylation of coreceptors may be required for Nodal signaling in Xenopus

https://t.co/us3XJT3XO7

#BodyAxisFormation #Cripto #Embryogenesis #Smad2 #Xnr1

[Molecules and Cells @MolCells]

2025 cover

[Molecules and Cells @MolCells]

Biallelic variants of SEMA3F are associated with nonsyndromic hearing loss

https://t.co/1eMMMZJfYD

#ExomeSequencing #HearingLoss #OuterHairCell #SEMA3F #SpiralGanglionNeuron

[Molecules and Cells @MolCells]

Tumor cells ectopically expressing the membrane-bound form of IL-7 develop an antitumor immune response efficiently in a colon carcinoma model

https://t.co/Vjo8xIB1HN

#CytokineGene–ModifiedTumorCells #Interleukin-7 #Membrane-BoundForm #TumorCellVaccine #TumorTherapy

[Molecules and Cells @MolCells]

Autophagic signatures in peripheral blood mononuclear cells from Parkinson's disease patients

https://t.co/kqzzHV2enA

#Autophagy-lysosomalPathway #Biomarkers #Lysosomal-AssociatedMembraneProtein1 #Optineurin #Parkinson’sDisease