Montagne Lab

Montagne lab @EdinburghUni.
We 🇲🇽🇸🇰🇺🇸🇬🇧🇭🇺🇨🇿🇨🇴🇮🇪🇪🇸🇪🇨🇦🇺🇫🇷🇲🇴🇳🇴🇳🇬🏴󠁧󠁢󠁳󠁣󠁴󠁿🇲🇦🇦🇷🇺🇦 study the blood vessels 🩸 in the brain 🧠

[Montagne Lab @MontagneLab]

🧠 An exciting fully funded 4-year PhD @EdinburghUni & @OfficialUoM with Drs. Ingo Schiessl, Audrey Chagnot, and myself!

📅 Deadline: Jan 9!

📝 Details are below 👇🏻

Please circulate this widely, thanks!

[Montagne Lab @MontagneLab]

🚀 PhD opening in our lab!

Join a collaborative team across the @alzheimerssoc VIDA DTC to study vascular mechanisms in Alzheimer’s disease, with access to cutting-edge imaging and molecular tools.

👉 https://t.co/m0s8vsfPZS

[Montagne Lab @MontagneLab]

https://t.co/ZldZmuX9tK

[Montagne Lab @MontagneLab]

Publication alert! 🤓🥳

Amazing teamwork led by @AudreyChagnot, @DanyJaimeGarcia, and @Conasaurus1!!! 🙌🏼

[Dr. Axel Montagne, PhD @AxL_Montagne]

It is now published in Acta Neuropathologica! 🎉

Congrats @AudreyChagnot, @DanyJaimeGarcia, @Conasaurus1 and team! 👏🏼

[Gou Young Koh (Gogh) @gou_koh]

Thrilled to share our new study showing how CSF crosses through arachnoid fenestrations to olfactory meningeal lymphatics: Cell https://t.co/YkUxvXrGsY A major step toward understanding CSF exit from subarachnoid space.

[Satchin Panda @SatchinPanda]

Disease causing mutations in each of these 11 genes are implicated in at least three different chronic diseases or lifespan in humans. #Aging #Longevity #Genetics
https://t.co/FszNqf5Y8z

[Montagne Lab @MontagneLab]

Congrats @DStefancova 🥳

[Dr. Axel Montagne, PhD @AxL_Montagne]

🚨 New preprint on bioRxiv!

Pericyte loss triggers hypoperfusion, BBB dysfunction, endothelial VCAM-1/type I IFN activation, venular-like transitions & delayed white matter injury linked to human cSVD signatures.

Congrats team!

https://t.co/VpLniJ83dv

[Dr. Axel Montagne, PhD @AxL_Montagne]

🚨 New preprint

11,000+ human brain microvessels in cSVD

• Early bimodal pericyte loss
• Later endothelial activation w/ a venous-like inflammatory shift
• ↑ capillary density with disease

💡 Suggests sequential vascular pathology, not parallel

🔗 https://t.co/WP25eBQ3Uv

[Dr. Axel Montagne, PhD @AxL_Montagne]

Here is the FindAPhD weblink to our BHF-DRI PhD programme!

Deadline: *April 14*

Please spread the word!!

https://t.co/SebnjI7nKa

[Dr. Axel Montagne, PhD @AxL_Montagne]

🚨 PhD Programme – Vascular Dementia Research

New 4-year PhD funded by BHF & UK DRI.

Training across UCL, Oxford, Leicester & Edinburgh with lab rotations.

📅 Deadline: 14 April
🎓 Start: Sept 2026

Apply: CV + statement + 2 refs > [email protected]

Please share!

[Alzforum @alzforum]

The “exerkine” GPLD1 confers cognitive benefit by removing an alkaline phosphatase from blood vessel walls, keeping brain vasculature youthful. #alzheimersdisease @UCSF https://t.co/WgFYYdEdgw

[Montagne Lab @MontagneLab]

📢 PhD fellowship opportunity in Edinburg 🏴󠁧󠁢󠁳󠁣󠁴󠁿
Deadline: Friday 9 📅
Apply now 👇🏻

[Montagne Lab @MontagneLab]

🧠 An exciting fully funded 4-year PhD @EdinburghUni & @OfficialUoM with Drs. Ingo Schiessl, Audrey Chagnot, and myself!

📅 Deadline: Jan 9!

📝 Details are below 👇🏻

Please circulate this widely, thanks!

[Montagne Lab @MontagneLab]

🚀 PhD opening in our lab!

Join a collaborative team across the @alzheimerssoc VIDA DTC to study vascular mechanisms in Alzheimer’s disease, with access to cutting-edge imaging and molecular tools.

👉 https://t.co/m0s8vsfPZS

[Dr. Axel Montagne, PhD @AxL_Montagne]

🚀 Fully funded 4-yr PhD @EdinburghUni & @OfficialUoM on the vascular origins of Alzheimer’s disease (advanced imaging + proteomics)

Supervisors are Drs. Axel Montagne, Ingo Schiessl, and Audrey Chagnot

Join the VIDA DTC & @alzheimerssoc partnership

👉 https://t.co/HtwLmJN6hh

[Alzforum @alzforum]

Scientists identified 49 proteins genetically linked to cerebral small vessel disease. This common co-pathology with #alzheimersdisease contributes to risk for ARIA. @wustl @UTokyo_News https://t.co/wtXcHtvgUN

[Dr. Axel Montagne, PhD @AxL_Montagne]

Excited to share our @CurrentBiology Primer written with @AudreyChagnot in the Brain-Body Interactions special issue!

We discuss how the BBB works, what happens when it breaks down, and why this matters for brain and body health.

@UKDRI @TheBHF

https://t.co/QnwkVuHEWh

[UK Dementia Research Institute @UKDRI]

🎉 This week, we’re proud to officially launch the BHF-UK DRI Centre for Vascular Dementia Research, in partnership with @TheBHF.

The centre will explore how changes in vascular health contribute to dementia - paving the way for new treatments👉 https://t.co/JrzeyVBGmD

[UK Dementia Research Institute @UKDRI]

🌟 New job opportunity 🌟

Based within the UK DRI at Edinburgh, the Rajani Lab investigates the mechanisms of white matter damage in vascular and other dementias.

Find out more and apply via the link

🗓️ Apply by 22 October 2025

📌 Full details 👉 https://t.co/b9S55fWeXL

[Dr. Axel Montagne, PhD @AxL_Montagne]

✨ Preorders are OPEN ✨

My amazing wife just finished her very first children’s book, and I couldn’t be prouder 💛

📚 Preorder until Sept 7
📦 Shipped w/ tracking
🔗 https://t.co/kUAL3THofn

She’s poured her heart into this — every preorder, share, & boost means the world 🙌

[Katerina Akassoglou @AkassoglouLab]

The first patient in Phase 1b trial for Alzheimer's disease has been dosed with the fibrin-targeting immunotherapy. I am deeply grateful to the patients, clinical centers, the team at Therini Bio, and all the scientists in my lab making the foundational discoveries on fibrin in neurological diseases and the first-in-class fibrin-targeting antibody. https://t.co/ed096Nmz1P

[Dr. Axel Montagne, PhD @AxL_Montagne]

🚨 Review Alert

*Walking on the tightrope: the shared roles of the bridging pericytes in the brain*

Congratulations Audrey Chagnot!! 🥳

Bias aside, this feels like a really meaningful piece for the cerebrovascular field! 😊

https://t.co/uFxN9J72Wp

[Dr. Axel Montagne, PhD @AxL_Montagne]

Well done @DanyJaimeGarcia 👏🤩

Blood biomarkers of vascular dysfunction in small vessel disease progression: Insights from a longitudinal neuroimaging study - Jaime Garcia - 2025 - Alzheimer's & Dementia - Wiley Online Library https://t.co/XgS5t5D2f4