NEJM

The New England Journal of Medicine is the world’s leading medical journal and website.

[NEJM @NEJM]

In the phase 3 TRIUMPH-1 trial involving patients with obesity, retatrutide, a triple hormone receptor agonist, resulted in substantial weight reduction and a decrease in knee osteoarthritis pain and obstructive sleep apnea events. Full trial results: https://t.co/kzuY57bUTX

[NEJM @NEJM]

Perspective essay by Christos P. Kotanidis, MD, DPhil (@cpkotanidis): Not Available in Your Country https://t.co/5Ej7if4Wj9

#AIinMedicine #MedEd

[NEJM @NEJM]

Correspondence: Integration-Associated Paraspinal Neoplasm after AAV Gene Therapy https://t.co/rUXHSpFHNw

#Neurology #Genetics

[NEJM @NEJM]

Full adherence to daily antiretroviral therapy for HIV can be challenging. In a phase 3b trial in Kenya, South Africa, and Uganda, a long-acting ART regimen was noninferior to daily ART use. Full IMPALA trial results and Research Summary: https://t.co/8dGWIhShcV

[NEJM @NEJM]

A new article summarizes the assessment and treatment of adult attention deficit–hyperactivity disorder, with an emphasis on common psychiatric and medical coexisting conditions and combined pharmacologic and psychosocial care. Full article with interactive graphic: https://t.co/g3BLDSKOW0

[NEJM AI @NEJM_AI]

On AI Grand Rounds, Dr. Michal Nedoszytko (@mnedoszytko) explains how AI can help physicians gather better information, improve the quality of conversations with patients, and prototype solutions to problems that clinicians experience every day. 🎧 https://t.co/W9u8Le66aY

[NEJM @NEJM]

Images in Clinical Medicine: Flushing in Carcinoid Syndrome https://t.co/B2wQLpveHu

#Oncology #Endocrinology

[NEJM @NEJM]

Presented at #SleepEurope2026:

In two phase 3 trials involving participants with OSA and obesity or overweight with or without type 2 diabetes, treatment with retatrutide was found to result in greater decreases in the apnea–hypopnea index than placebo. Full results of the TRIUMPH-1-OSA and TRIUMPH-2-OSA trials: https://t.co/C7KEyEsdbz

@ESRS_Sleep

[NEJM @NEJM]

Perspective by Paula Amato, MD, and I. Glenn Cohen, JD: Who Counts as Infertile? A Missed Opportunity for Inclusion https://t.co/nRSoLVnENm

#GlobalHealth #MedicalEthics

[NEJM @NEJM]

In a new NEJM Voices blog post, @MKittlesonMD shares how work in medicine can uncover surprisingly inspiring and undeniably human stories. Read the post and sign up for email alerts: https://t.co/mZvjmh8dsa

[NEJM @NEJM]

Correspondence: Once-Weekly Mosnodenvir as Dengue Prophylaxis in a Human Infection Model https://t.co/fCqT6cC1ZC

#InfectiousDisease #GlobalHealth

[NEJM @NEJM]

For patients with atrial fibrillation and an intermediate risk of stroke, guidelines suggest that oral anticoagulation should be considered, but is this the best approach? Our latest video in partnership with @DGlaucomflecken explains new research. Full trial results: https://t.co/SxPcHS6ghK

[NEJM @NEJM]

Perspective by Mark A. Unruh, PhD, and Joshua R. Vest, PhD, MPH: Health-Related Social Needs among Older Adults — Addressing Mismeasurement https://t.co/NzjEnaDYAg

#MedicalPractice #PublicHealth

[NEJM @NEJM]

In a phase 2 trial of once-daily oral icotrokinra for moderately to severely active ulcerative colitis, a clinical response at week 12 was more common with icotrokinra at each of three tested doses than with placebo. Full ANTHEM-UC trial results and Research Summary: https://t.co/7eIxOmiORk

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Images in Clinical Medicine: Alkaptonuria https://t.co/LMqtbVT8rP

#Rheumatology

[NEJM Evidence @NEJMEvidence]

An 18-year-old woman sought evaluation in the emergency department because of abdominal pain that had begun 3 days earlier. The pain was acute in onset and generalized throughout the abdomen. Read the full case details in a new Morning Report: https://t.co/OmzCoRKKwd

[NEJM Catalyst @nejmcatalyst]

A study on the impacts of e-patient visits on outpatient volume and service time provides guidance for health care admins to optimize e-visit service mechanisms by restructuring the unplanned, open-access online consultation entry for patients. See how: https://t.co/QTiW4mL1tN

[NEJM @NEJM]

In a new NEJM Voices blog post, Don Dizon, MD, explains why, as an oncologist, he cannot be satisfied with the current standards of care for cancer patients. Read the full post and sign up for email alerts: https://t.co/0KLffbtEb0

[NEJM @NEJM]

Original Article: Long-Acting HIV Therapy in African Adults with Adherence Challenges (phase 3b IMPALA trial) https://t.co/8dGWIhShcV

#InfectiousDisease #GlobalHealth

[NEJM @NEJM]

A new trial compared intermittent hemodialysis with continuous renal-replacement therapy as initial treatment for acute kidney injury in critically ill adults. Research findings from the ICRAKI trial are summarized in a new Quick Take video. https://t.co/uR7BLXJyDP

[NEJM @NEJM]

In a new NEJM Voices blog post, @PaulSaxMD shares good news for people with HIV, easier access to a very strange antibiotic, and a thank-you to someone who deserves it. Read the full post and sign up for email alerts: https://t.co/rmvxJ2rpZm