Neurogastro & Motil

EIC: @IBS_Maastricht Eds: @nicolascenac @AndreaShin_GI DReed @NehaSantucciMD AMalcolm KSmithEdwards @Pierfra_Visaggi @ThisIsButt KElfers WMorales @Rajan___Singh

[Neurogastro & Motil @NGMJournal]

🚨Thrilled to welcome the new #EditorialTeam at @NGMJournal led by our new Editor-in-Chief, Prof. Daniel Keszthelyi @IBS_Maastricht🎉
📢We look forward to great science & fascinating breakthroughs ahead in #Neurogastroenterology & #Motility #GutBrainScience
@ANMSociety @esnm_eu

[Neurogastro & Motil @NGMJournal]

🆕🔥Systematic Review: Role of Pyloric Dilation #PyD in the Management of #Gastroparesis‼️
✅Clinical utility of PyD👏
🎯PyD may be a low-risk option for symptom relief in select gastroparesis patients across all age groups
👉https://t.co/kgEl0pyab8
@ANMSociety @esnm_eu

[Neurogastro & Motil @NGMJournal]

🆕🔥Age-related reductions in colonic Neurokinin A #NKA‼️
🎯A 3D-printed immunosensor detected⬇️NKA content & release in the aged colon
💡Fecal NKA mirrored tissue changes, highlighting a potential noninvasive biomarker of bowel aging. #Bowel dysfunction
👉https://t.co/BtHCHd2Dkq

[Neurogastro & Motil @NGMJournal]

🆕🔥Age-related reductions in colonic Neurokinin A #NKA‼️
🎯A 3D-printed immunosensor detected⬇️NKA content & release in the aged colon
💡Fecal NKA mirrored tissue changes, highlighting a potential noninvasive biomarker of bowel aging. #Bowel dysfunction
👉https://t.co/BtHCHd2Dkq

[Neurogastro & Motil @NGMJournal]

🔥Real-world patient perspectives on FDA-approved therapies for #IBS with #Constipation‼️
7328 publicly available online posts
4⃣Themes: Perceived medication efficacy, Treatment burden, Intentional non-adherence, & Adherence barriers
👉https://t.co/A4Go0pWcHs
@ANMSociety @esnm_eu

[Neurogastro & Motil @NGMJournal]

🆕🔥Transcutaneous auricular vagal nerve stimulation #taVNS effectively⬇️#AbdominalPain & #Anxiety/depression in patients with #IBS & patients with #FunctionalDyspepsia‼️
🎯Autonomic mechanism of taVNS #Enhancing #vagal activity💡
👉https://t.co/fyEOB9wmV8
@ANMSociety @esnm_eu

[Neurogastro & Motil @NGMJournal]

🆕🔥Muscularis EGR1 deficiency impairs #Macrophage polarization & disrupts #GastricMotility in #DiabeticGastroparesis‼️
🎯EGR1 restoration improves gastric emptying & pyloric slow-wave regularity
👉https://t.co/Gg3qbCEcaD
@ANMSociety @esnm_eu
Master regulator of #GastricMotility

[Neurogastro & Motil @NGMJournal]

🆕🔥Transcutaneous auricular vagal nerve stimulation #taVNS effectively⬇️#AbdominalPain & #Anxiety/depression in patients with #IBS & patients with #FunctionalDyspepsia‼️
🎯Autonomic mechanism of taVNS #Enhancing #vagal activity💡
👉https://t.co/fyEOB9wmV8
@ANMSociety @esnm_eu

[Neurogastro & Motil @NGMJournal]

🆕🔥Muscularis EGR1 deficiency impairs #Macrophage polarization & disrupts #GastricMotility in #DiabeticGastroparesis‼️
🎯EGR1 restoration improves gastric emptying & pyloric slow-wave regularity
👉https://t.co/Gg3qbCEcaD
@ANMSociety @esnm_eu
Master regulator of #GastricMotility

[Neha Santucci MD MBBS MS AGA-F @NehaSantucciMD]

DGBI Rome 5 criteria are out! As the assoc editor, I encourage all to submit, esp peds GI with the new peds criteria. Will they change clinical mgt? We want to hear your thoughts! @NASPGHAN @ANMSociety @RomeFoundation @RomeGastroPsych @IFFGD @AmerGastroAssn @AmCollegeGastro

[Neurogastro & Motil @NGMJournal]

📢Call for Papers ✅Special issue @NGMJournal🔥
🚨The Rome Diagnostic Framework: Reflections on the Past and Perspectives for the Future‼️
🎯Where should the field go next❓
🔗 https://t.co/MChYZyR6uK
@ANMSociety @esnm_eu #DGBI
🚨Join us in advancing the conversation

[Neurogastro & Motil @NGMJournal]

📢Call for Papers ✅Special issue @NGMJournal🔥
🚨The Rome Diagnostic Framework: Reflections on the Past and Perspectives for the Future‼️
🎯Where should the field go next❓
🔗 https://t.co/MChYZyR6uK
@ANMSociety @esnm_eu #DGBI
🚨Join us in advancing the conversation

[Neurogastro & Motil @NGMJournal]

🆕🔥Beyond #Snapshot: Overcoming #GES limitations to characterize gastric phenotypes & therapeutic responses using a 6Day #AmbulatoryWearableMonitor‼️
🎯Continuous monitoring may better reflect real-world GI function #Gastroparesis💡
👉https://t.co/6b9684585X
@ANMSociety @esnm_eu

[Neurogastro & Motil @NGMJournal]

🆕🔥GI providers prescribed #RestrictiveDiets to ~20% of patients with #EatingDisorders seeking gastroenterology care‼️
🎯Providers prescribed these diets to 16% with preexisting eating disorders—over half were not in remission💡
👉 https://t.co/bIN5U7QcOZ
@ANMSociety @esnm_eu

[Neurogastro & Motil @NGMJournal]

🆕🔥#TRPM8 protects against DSS-induced colitis‼️🐭
🎯TRPM8 regulates #CGRP release from sensory #neurons & IL-10 production in enteric #macrophages
⏩Revealing a protective #neuroimmune pathway during intestinal inflammation💡
👉 https://t.co/vEflzMjyap
@ANMSociety @esnm_eu

[Neurogastro & Motil @NGMJournal]

🆕🔥#TRPM8 protects against DSS-induced colitis‼️🐭
🎯TRPM8 regulates #CGRP release from sensory #neurons & IL-10 production in enteric #macrophages
⏩Revealing a protective #neuroimmune pathway during intestinal inflammation💡
👉 https://t.co/vEflzMjyap
@ANMSociety @esnm_eu

[Neurogastro & Motil @NGMJournal]

🆕🔥GI providers prescribed #RestrictiveDiets to ~20% of patients with #EatingDisorders seeking gastroenterology care‼️
🎯Providers prescribed these diets to 16% with preexisting eating disorders—over half were not in remission💡
👉 https://t.co/bIN5U7QcOZ
@ANMSociety @esnm_eu

[Rajan Singh @Rajan___Singh]

Thrilled to share our recent #Editorial @NGMJournal🆕🔥
📢From Symptoms to Signatures: Proteome-Defined Endotypes in #FunctionalDyspepsia‼️
With Prof. @BMoshiree 🙏😇
⏩FD patients who appear clinically indistinguishable often harbor fundamentally different mucosal programs. Some are dominated by microbial🦠-triggered #immunity in the stomach; others by type-2 inflammation, oxidative stress, or #mast-cell–neural crosstalk in the duodenum💡
🎯The next era should integrate the #Rome V multidimensional clinical profile—capturing both the lived illness experience with biomarkers revealing underlying tissue micro-organic pathology and the circuits that drive it👏
📌#Mechanism-guided, #precision neurogastroenterology offers genuine hope for novel #therapeutics that restore gut-brain🧠homeostasis.
✅ In FD, as in so many #DGBIs, the pathophysiological basis should ultimately guide treatment decisions more than symptom similarity🙌
👉https://t.co/xWM5Irofie🙏😇
#Neurogastroenterology #Motility #DGBI #GutBrainAxis
@ANMSociety @esnm_eu @AmerGastroAssn @AmCollegeGastro @my_ueg @RomeFoundation @GMFHx @unrmed @NYUPainResearch @MargolisLabNYU @RomeGastroPsych @GIL_trainee @IFFGD @INMAssociation @anma_i @ANGMA_AU @MRC_microbiome @ENSP_mayo @TARGID_KULEUVEN👏

[GutMicrobiota Health @GMFHx]

Is there a potential role of proteome-defined endotypes in functional dyspepsia?

@Rajan___Singh & @BMoshiree highlight the need of gaining better insights into functional dyspepsia's mechanisms of action for better therapeutic management

@NGMJournal 

https://t.co/5EFDGkG8xt

[Neurogastro & Motil @NGMJournal]

🆕🔥Bodily Maps of #Emotions in #IrritableBowelSyndrome‼️
🎯#IBS participants have altered embodiment of #EmotionalStates,⬆️abdominal sensations, ⬇️emotional differentiation, & blunted abdominal representation of positive emotions💡
👉https://t.co/Tl91jwdFsk
@ANMSociety @esnm_eu

[Neurogastro & Motil @NGMJournal]

🆕🔥Expert Clinical #Consensus on #BodySurfaceGastricMapping Phenotypes for #Gastroduodenal Disorders: ‘Auckland Classification’ v1.0‼️
🎯Evidence & mechanism-based treatment options are suggested for each BSGM-defined phenotype💡
👉 https://t.co/ukrKnxv0Jq
@ANMSociety @esnm_eu