Nacho

PhD student at CNIC. Immunology and metabolism. Basket and Chinese language

[David Sancho @SanchoLab]

🤔Do you think that OXPHOS in DCs = tolerance?
🚨In our new @Cell_Metabolism study @CNIC_CARDIO , we show that active #mitochondrial ETC primes cDC1s for immunogenicity, boosting anti-tumor immunity.
Life (and #immunometabolism) is not simple ⚡️(1/9)
OPEN: https://t.co/4CLH4xad9Y

[Waggoner Lab @LabWaggoner]

Mitochondrial metabolism regulates the immunogenic responsiveness of dendritic cells @Cell_Metabolism
https://t.co/diPFmWG15l @SWculek @IRBBarcelona

[Cell Metabolism @Cell_Metabolism]

New! Online now: Mitochondrial metabolism regulates the immunogenic responsiveness of dendritic cells https://t.co/5bUTzfdH8O

[David Sancho @SanchoLab]

🚨Put a dendritic cell (DC) in your tumor #immunotherapy!
cDC1-based vaccines induce strong effector & memory anti-tumor T cell response. Improved immune memory prevents tumor relapse! @CNIC_CARDIO @AgEInves @contracancerINV @FundlaCaixa @WorldwideCancer
https://t.co/cQYphYAoxX

[Jose Espejo Valle-Inclan @je_valleinclan]

After a hectic summer, a new and extremely exciting adventure has started. I will be leading the cancer genomics group at the newly created Botton-Champalimaud Pancreatic Cancer Centre in Lisbon, Portugal! 🍀💫☀️ @ChampalimaudF @Neuro_CF

[Miguel @mappatore_]

Todos los tifos de la @DemenciaEstu en los últimos 10 años.

🧵⬇️

[David Sancho @SanchoLab]

🙏RT
📅Abstract deadline DC2024 Barcelona 30th May
🚨 SUBMIT NOW 👇
https://t.co/ujuSt2Dk5q
🔬34 short talks + posters!!!
🔝🌍speakers
https://t.co/5758hOZEzZ
support by: @SEinmunologia @SCImmunologia @EuMacDcSoc
Sponsors:
🥇@miltenyibiotec
🥈@inmunotek
🥉@BioLegend
@EMBO

[Carlos Minutti @CarlosMMinutti]

Delighted to share our latest work, out in @NatImmunol, tackling the seemingly inordinate complexity of #cDC2s. @ReiseSousaLab @TheCrick, we found that distinct ontogenetic lineages dictate cDC2 heterogeneity, rather than cell states imposed by the tissue microenvironment 🧵(1/x)

[David Sancho @SanchoLab]

Our latest review on DCs in anticancer immunity @NatRevClinOncol updates on DC lineages and states in the tumor in the single-cell era, diversity in different human cancers, clinical trials, DCs in current & future cancer immunotherapy.
Free link: https://t.co/Nk3rY5AbV3

[Jose Espejo Valle-Inclan @je_valleinclan]

To celebrate the new year, our work on complex genome rearrangement in osteosarcomas! Many thanks to all co-authors, in particular Solange de Noon, Adrienne Flanagan from @uclcancer and @isidrolauscher. Preprint at https://t.co/hYLFWFLL1I and thread below, by @isidrolauscher 👇

[Nacho @NachoHM3]

Looking forward!

[Jose Gomez Rial @gomez_rial5]

Se acaban de publicar (1ª vez en humanos) los resultados fase I de una vacuna frente al #VIH q induce Ac neutralizantes de amplio espectro, frente a múltiples serotipos del virus, mediante la estrategia de vacunación dirigida a "linea germinal"
https://t.co/RKEYJieYoQ

[Xiao Huang 黄潇 @XiaoHuangNano]

Our Precision Immune Engineering Lab website is finally live 🍾🎆 We are recruiting MS and PhD students!! Pls check our website if you are interested in therapeutic T cell engineering and send an inquiry to me with a CV👇👇 https://t.co/QK8vbEfDU4

[Patrimonio de Tetuán @PatrimonioTetu1]

Buenas noches #tetuaneros❕❗️❕ Hoy vamos a hablar de como un mareo comunitario y vecinal ha ido derivando a nuevos proyectos y nuevos materiales. Incluso creando mapas!! porque se pueden crear y todo...

y...

¿A quién no le gustan los mapas?

[FPU Investiga @FPUinvestiga]

Cada punto es importante porque afecta a un/a compa del sector de la #investigación.

Este #7F te esperamos‼️✊

[Nacho @NachoHM3]

Game changer!

[Prof. Akiko Iwasaki @VirusesImmunity]

Vaccines that reduce infection & disease are needed to combat the pandemic. Here, @tianyangmao @BenIsraelow et al. describe our new mucosal booster strategy, Prime and Spike, to induce such immunity via nasal delivery of unadjuvanted spike vaccine 🧵 (1/)

https://t.co/J4NuUgiI7e

[Jose Gomez Rial @gomez_rial5]

Al hilo de la decisión de administrar 3a dosis de forma generalizada >18a, explico mi posición en contra aunque avanzo q echo mucho de menos un debate serio en sede oficial con las soc científicas implicadas antes de tomar estas decisiones 👇🏼👇🏼👇🏼

[Tony Breu @tony_breu]

1/
Why does cold air make my kids' noses runny?

A weekend of playing in the snow made me wonder. I didn't do a deep dive but thought I'd share what I learned.

[Salva Iborra @salva_iborra]

Charles Janeway necesitó años de estudio e investigación, para proponer en 1989 que, para que una respuesta inmunitaria tenga lugar, hacen falta 2 tipos de señales: el antígeno, reconocido por los linfocitos y un adyuvante, reconocido por las células de la inmunidad innata.🧵

[Mónica García @Monica_Garcia_G]

Solo hay una cosa peor que no tomar medidas: tomar medidas inútiles.