Nature Cardiovascular Research

Online-only Nature Research journal that publishes basic, translational, clinical and public health research in cardiac, vascular and blood biology.

[Nature Cardiovascular Research @NatureCVR]

❤️Our March issue is out❤️Read about an AI model using echocardiography images improves cardiac diagnosis, LVAD unloading alleviates cellular senescence, inhibition of a hematopoietic death regulator shows cardioprotection, and more.

https://t.co/lMEE4jJVgB

[Nature Cardiovascular Research @NatureCVR]

❤️Our February issue is out❤️Read about self-powered stent for real-time monitoring, cardiomyocyte regeneration through glucocorticoid receptor antagonism, immunometabolic targeting for type 2 diabetic cardiomyopathy, and more.

https://t.co/YiCUE1Id3X

[Nature Cardiovascular Research @NatureCVR]

Research | Lazarevic et al. reveal a shared loss of a TBX5-dependent atrial gene network in cardiomyocytes and a disease-specific network gain in activated fibroblasts across atrial fibrillation and heart failure models.

https://t.co/xhQLMb9112

[Nature Cardiovascular Research @NatureCVR]

Research | Chen et al. developed a self-powered smart magnetoelastic stent for real-time hemodynamic monitoring and stenosis detection.

https://t.co/NO3BddKRsy

[Nature Cardiovascular Research @NatureCVR]

Research | Da Pra et al. show physiological glucocorticoids suppress GF-induced CM regeneration by inhibiting ERK signaling and propose glucocorticoid receptor antagonism as a strategy to enhance their regenerative effects.
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[Nature Cardiovascular Research @NatureCVR]

❤️Our January issue is out❤️Read about pathogenic mechanism of mutated ribosomal protein PRL3L, identification of cardiac progenitor lineage linked to congenital heart disease, multimodal vision graph for drug repurposing, and more.

https://t.co/x8L6MVzayY

[Nature Cardiovascular Research @NatureCVR]

Research | Kathiriya et al identify a cardiac Tbx5+/Mef2cAHF+progenitor lineage that bisects the intraventricular septum during the development and show that alterations in this lineage lead to congenital heart disease.

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[Nature Cardiovascular Research @NatureCVR]

Big thanks to the Science Ministry of Serbia, Drs. Knoblich, Guilliatt, Stewart, & Turco, and Profs. Radisic, Hedtrich, Clevers, Vunjak-Novakovic, Trayanova, Lütolf, Heilshorn, Dvir, Cho & Singh for the great event! @milicaruoft @GVNlab @TheCleversLab

https://t.co/DkcALQNLEV

[Nature Cardiovascular Research @NatureCVR]

❤️Our December issue is out❤️Read about a method to measure mitochondrial membrane potential in intact hearts, gene therapy for myocardial infarction, genetic association between thromboembolism and long COVID, and more.

https://t.co/abaFl4PWQJ

[Nature Cardiovascular Research @NatureCVR]

Research | Neo et al. map blood emergence from three hemogenic endothelial (HE) populations biased toward distinct blood fates. HE primed for stem progenitors shows elevated chromatin and RNA splicing gene expression.
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[Nature Cardiovascular Research @NatureCVR]

❤️Our November issue is out❤️Read about an imaging method that combines cardiac electrophysiology with 3D structural heart reconstruction, a targeted glycophagy ATG8 therapy reversing diabetic heart disease, and more.

https://t.co/H88Oi2txcO

[Nature Cardiovascular Research @NatureCVR]

Research | Chan et al. generate a high-resolution spatiotemporal atlas of healing hearts and reveal cellular networks of lesion repair, including macrophage-fibroblast interactions that control late-stage fibrosis.

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[Nature Cardiovascular Research @NatureCVR]

Research | Chen, Wang, Zhong and colleagues show that females derive greater cardiovascular benefits from guideline-recommended levels of physical activity and require less activity than males to see their beneficial effects.
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[Nature Cardiovascular Research @NatureCVR]

Research | Tan et al. identify PRDM16 as a key repressor of fibrotic switching in smooth muscle cells and show that its downregulation in atherosclerosis drives smooth muscle cells toward a synthetic fate, promoting fibrous plaques.
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[Nature Cardiovascular Research @NatureCVR]

Research | Lin, Geng et al. identify a non-canonical AHR pathway that is activated by canonical AHR inhibitors, promoting the proliferation of quiescent endothelial cells with potential applications in cell therapy.

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[Nature Cardiovascular Research @NatureCVR]

Research | Amiad Pavlov, Heffler et al. demonstrate that stress transmitted to the cardiomyocyte nucleus by the microtubule cage drives LMNA-associated cardiomyopathy and may represent a promising therapeutic target.

https://t.co/PpVWzJYfIy

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[Nature Cardiovascular Research @NatureCVR]

Research | Yamazoe et al. show that B-cell derived autoantibodies contribute to the development of atrial fibrillation, suggesting that targeting the humoral immune response may represent a viable therapeutic approach.

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[Nature Cardiovascular Research @NatureCVR]

Research | Mulholland et al. identify progenitor exhausted T cells, expressing intermediate levels of PD-1, as a prominent source of pro-inflammatory cytokines in the murine atherosclerotic aorta and potential cellular targets.
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[Nature Cardiovascular Research @NatureCVR]

❤️Our October issue is out❤️Read about the RNA editing enzyme ADAR1 regulating atherosclerosis progression, PGC-1α and cardiac adaptation to exercise training, the role of LYVE1-macrophages in heart regeneration and peripheral artery disease, and more.

https://t.co/6IDTiQSHE7

[Nature Cardiovascular Research @NatureCVR]

Research | Barbera et al. identify and map genetic variants that alter the characteristics of vascular smooth muscle cells and contribute to the risk of coronary artery disease.

https://t.co/B4flCE8pcV

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