Nature Methods

Nature Methods publishes cutting-edge methods, tools, analyses, resources, reviews, news and commentary, supporting life sciences research. Tweets by editors.

[Nature Methods @naturemethods]

Read the associated Research Briefing here:

https://t.co/NBBfh3XWat

[Nature Methods @naturemethods]

Neuropixels Opto probes combine high-density recording sites with optical waveguide-based light emission sites to simultaneously record neuronal activity and optogenetic stimulation.

https://t.co/algKfatbaQ

[Nature Methods @naturemethods]

TADShop: a study benchmarking 43 computational methods for identifying topologically associating domains.

https://t.co/9R49yjE5Rg

[Nature Methods @naturemethods]

Read the News & Views highlighting this work, here:

https://t.co/ZpCjIEQY4h

[Nature Methods @naturemethods]

A correlative workflow combining cryo-EM and focused ion beam secondary ion mass spectrometry enables subcellular chemical mapping.

https://t.co/f9Q3l2hPOr

[Nature Methods @naturemethods]

Read the News & Views highlighting this work, here:

https://t.co/oBfVXYUjvR

[Nature Methods @naturemethods]

Decima learns to predict cell-type-specific gene expression based on DNA sequences.

https://t.co/JkwefHvaxV

[Nature Methods @naturemethods]

High multiplicity of infection sgRNA multiplexing maintains CRISPRi screen performance while enabling reduced cell numbers.

https://t.co/V0tdM0vlwO

[Nature Methods @naturemethods]

AreTomoLive: a preprocessing pipeline for cryo-ET that streamlines tomographic alignment, reconstruction and contrast enhancement.

https://t.co/alZFsI4vhM

[Nature Methods @naturemethods]

ENCORI is a comprehensive analysis platform and resource for exploring RNA-protein and RNA-RNA interactomes.

https://t.co/SBj4mTdOtS

[Nature Conferences @NatureConf]

How are electron microscopy, methods and AI advancing physical and life sciences? Find out at our upcoming event featuring global experts and organized by @PrincetonMSE, @Nature, @naturemethods, @NatureCatalysis & @NatureMaterials

Learn more>>https://t.co/2RFfo8EU7E

[Nature Methods @naturemethods]

MOSAIC: a versatile multimodal microscopy that seamlessly transitions between light-sheet, 2-photon, label-free and super-resolution modalities. @Eric_Betzig @ABCUCBerkeley @legant_lab

https://t.co/l3NtYh3OrD

[Nature Methods @naturemethods]

StringTie3 shows enhanced performance in total RNA-seq assembly and quantification. @elapertea

https://t.co/Pgn5cAbC42

[Nature Methods @naturemethods]

A resource of lncRNA diversity in cancer at single cell resolution with spatial context.

https://t.co/ZinpYrX9EO

[Nature Methods @naturemethods]

A device for simultaneous photometry and electrophysiology allows recordings in freely moving mice without restricting movement and without cable entanglement. @ColumbiaPsych

https://t.co/BRCPYU5eV4

[Nature Methods @naturemethods]

And read the Research Briefing highlighting the work, here:
https://t.co/oQMO1UGRTU

[Nature Methods @naturemethods]

FILM: a mid-IR photothermal microscopy method for gentle imaging of metabolic processes in cells and worms. @HHMIJanelia @HHMI_science

https://t.co/555dSPPS71

[Nature Methods @naturemethods]

Hypothesis generation is fundamental to science. What happens when we outsource this task to a machine?

In this month's Editorial we explore the potentially disruptive shift of using AI for hypothesis generation.

https://t.co/LlZ02TZLjy

[Nature Methods @naturemethods]

Our May issue is live! 🎉
https://t.co/hSay4udgOR

On the cover, volumetric label-free imaging of a live model of the human blood–brain barrier with a self-localized ultrafast pencil beam. Paper here: https://t.co/BFs6rfx1Dj

[Nature Methods @naturemethods]

The story includes: Marinka Zitnik, James Zou, Kasper Lage, Eric Sun, Florian Jug, Fengqing Jiang, Sungsoo Ahn, Yunhui Jang.

[Nature Methods @naturemethods]

AI agent systems built atop large language models can do autonomous analyses. In a news feature our journalist asks scientists about considerations when choosing among AI agent systems for their work.

https://t.co/vPT3TjIBVo