Neal Callaghan

MD student at Dalhousie Med. PhD from IBME (UofT). Interests in #precisionmedicine, #tissueengineering, #STEMeducation, #quantitativeanalysis, and #fish.

[Neal Callaghan @NealCallaghan1]

@DrPietvanVliet Let us know how it goes!

[Neal Callaghan @NealCallaghan1]

@TheSurajKannan The disease modeling literature reflects perturbed membrane-associated proteomes, PTM states and splicing, whether causative or secondary to the altered homeostasis. Would be great to start querying these in PSC-CM maturation, but in vivo controls for proteomics are tough.

[Neal Callaghan @NealCallaghan1]

@TheSurajKannan This is in clear contrast to in vivo CMs, which your lab has demonstrated to have a much more evident trajectory toward "maturity".

[Neal Callaghan @NealCallaghan1]

Thanks to @craigsimmons11, @seema_mital, @milicaruoft, @FilioBillia, and all the other coauthors @trogersresearch for the wildest PhD project I could have imagined! (20/20 = I'm done now)

(cyan DAPI/nuclei, magenta SERCA2a, yellow RyR2)

[Neal Callaghan @NealCallaghan1]

Excited to share our new preprint coming out of @TBEP_UofT, where we demonstrate enhanced physiological maturation of stem cell-derived cardiomyocytes (heart muscle cells)!
https://t.co/EjeU3W7ISW (1/20)

[Neal Callaghan @NealCallaghan1]

Want to try C16 in your own lab? Go crazy! The recipe is in the preprint. Drop us a note if you want to chat more about how we use it, or how it was developed. (19/20)