Nele Quast

PhD in ML for structural bioinformatics @OPIGlets @UniofOx

[Nele Quast @NeleQuast]

We are looking forward to community contributions as more TCR structure research is conducted. We have also written some developer guidelines; if you have any questions just reach out!

This will be my last tweet: https://t.co/ZfIlbgwEw1
3/3

[Nele Quast @NeleQuast]

Do you wish working with T-cell receptor structures was easier?
Us too!

STCRpy, our software suite for TCR structure parsing, interaction profiling and machine learning dataset preparation is now available!

Github: https://t.co/VdRKvUfTwS
Pre-print: https://t.co/Qh65gi5Lm2
1/3

[Nele Quast @NeleQuast]

Big thanks to my supervisors Charlotte Deane and
@mijr12 for their supervision creating STCRpy. And all
@OPIGlets for being such a fab group to be part of! 2/3

[Nele Quast @NeleQuast]

@OPIGlets @NeurIPSConf @workshopmlsb @LucyVost I'll be presenting initial findings of our approach to protein flexibility estimation via uncertainty quantification. Drop by the poster session and check out the paper to find out more! https://t.co/AwIn0h2rYK

[Nele Quast @NeleQuast]

I'll be presenting initial results or our new approach to protein flexibility estimation via uncertainty quantification at @workshopmlsb today. Drop by the poster session and check out the paper to find out more! https://t.co/AwIn0h2rYK

[Oxford Protein Informatics Group (OPIG) @OPIGlets]

The @OPIGlets are out in force at  @NeurIPSConf - check out our work at the @workshopmlsb and AIDrugX workshops today.

@lucyvost, @nelequast and Nikhil Branson are presenting work on diffusion for small molecules, protein flexibility estimation and deep drug response models!

[Nele Quast @NeleQuast]

Huge thanks to all my collaborators from @OPIGlets and @Immunocore on this project, @brennanaba, Bora Guloglu, Vijaykumar Karrupiah, Stephen Harper, @mijr12, and Charlotte Deane

[Nele Quast @NeleQuast]

I'm delighted to announce that our work on TCRBuilder2+, our high-throughput deep learning model for predicting #TCR structures, trained on over 50% more data than previous models, is now available as a preprint: https://t.co/67jIz6Yj99

Summary and links below ->

1/5

[Nele Quast @NeleQuast]

TCRBuilder2+ pre-print: https://t.co/67jIz6Yj99

Structure predictions of over 1.5 million TCRs: https://t.co/jLpqk2aBMO

Pip installable code: https://t.co/0Vp6DGRg1k

Observed T-cell receptor Space: https://t.co/Edpasth7Do

4/5

[Nele Quast @NeleQuast]

I've posted my first @OPIGlets blog summarising the Graphormer DL architecture! https://t.co/2sm4SejMsn

[TCN Coalition @TCNCoalition]

Headed in the right direction. The NHS moves to "examine the feasibility of moving the app to the decentralised model ... being chosen by more and more European countries"

[Ito @itoApp]

Thanks to @BBCWorld for having us! We hope it helped to get a better understanding of the app we're offering. FYI: any help is very welcome, as we're an open source community.
#decentralized #opensource #Covid_19

[Anna Bacciarelli @a_bacci]

The u-turn in Germany is in huge part thanks to coordinated, speedy, relentless work from civil society. I’m in awe of friends and colleagues working tirelessly to stop the worst case scenario playing out on so many fronts right now.

[Ito @itoApp]

Working together with @TU_Muenchen on our app. So glad the german government picked up our decentralized approach with the @TCNCoalition protocol!

[CCC Updates @chaosupdates]

Kurswechsel der Bundesregierung bei der #CoronaApp – Bundeskanzleramtschef Helge Braun: Wir „werden wir eine dezentrale Architektur vorantreiben, die die Kontakte nur auf den Geräten speichert und damit Vertrauen schafft“ https://t.co/T6SDiWE51x

[Ito @itoApp]

As one of the founding members of the @TCNCoalition, we're proud that @SZ has picked up our joint statement. Thanks to @SimonHurtz.
BTW, ito has pitched the app at the @MinVWS appathon in the Netherlands this weekend.

https://t.co/uY3Wa0uHio

#trackinfectionsnotpeople #COVID19

[Ito @itoApp]

BTW: We are an open-source community and 100% open for any collaboration. We do NOT promote competitive behaviour and wish to see more joint forces on this project. That's the reason we decided to be a founding member of the @TCNCoalition