neuroimaging_neuroimmunology

Neuroimaging in Neuroimmunology & other cases

[neuroimaging_neuroimmunology @NeuroimagingN]

Definite neurosarcoidosis
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Another presentation of neurosarcoidosis. This time, it looks similar to an abscess. Biopsy showed noncaseating granulomas. After 4 years of treatment, there is a significant improvement in the lesion appearance.

#neurology #neurotwitter #MedTwitter

[neuroimaging_neuroimmunology @NeuroimagingN]

Disseminated coccidioidomycosis
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Profound leptomeningeal involvement

#coccidioidomycosis #disseminatedcoccidioidomycosis #neurotwitter #Neurology #MedTwitter #neuroradiology

[neuroimaging_neuroimmunology @NeuroimagingN]

Parry Romberg syndrome
Slowly progressive facial hemiatrophy. It can be associated with brain changes as well. Etiology unknown but thought to be autoimmune. Patients can present with seizures and migraines.
Green arrows show asymmetry between both sides.

#Neurology

[neuroimaging_neuroimmunology @NeuroimagingN]

Gliomatosis cerebri
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Biopsy proven

#gliomatosiscerebri #neurooncology #neurology #neuroinflammation #neuroimaging #neurology #neuroradiology #oncology #neurosurgery #neurotwitter

[neuroimaging_neuroimmunology @NeuroimagingN]

Probable neurosarcoidosis
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Involvement of the brain, spinal cord, and meninges.

#Neurosarcoidosis #probableneurosarcoidosis #neuroimaging #neurology #neurotwitter #NeuroRad #radiology #MedTwitter #MedEd

[neuroimaging_neuroimmunology @NeuroimagingN]

CNS blastomycosis
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Blastomyces dermatitidis

#CNSblastomycosis #blastomycesdermatitidis #blastomycosis #neuroinfectiousdiseases #neuroinflammation #neuroimmunology #neurology #neurosurgery #infectiousdiseases #neuroradiology

[neuroimaging_neuroimmunology @NeuroimagingN]

Acute necrotizing encephalopathy of childhood (ANEC)

#acutenecrotizingencephalopathyofchildhood #ANEC #ADEMlike #neuroimmunology #neurotwitter #MedEd

[neuroimaging_neuroimmunology @NeuroimagingN]

Metachromatic leukodystrophy
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Autosomal recessive. Mutation in the ARSA gene leads to arylsulfatase A deficiency. Lysosomal storage disease.
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U-fibers are initially spared

#metachromaticleukodystrophy #arylsulfataseadeficiency #lysosomalstoragedisorder #neurology #Pediatrics

[neuroimaging_neuroimmunology @NeuroimagingN]

Hyperintense cortical signal on T1 pre-GAD
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In the setting of Progressive multifocal leukoencephalopathy (PML)

#PML #immunodeficiency #neuroinfectiousdiseases #neuroinflammation #neuroimmunology #neurology #neuroradiology #radiology #neurosciences #neurotwitter

[neuroimaging_neuroimmunology @NeuroimagingN]

Steroid-responsive brain inflammatory process

Reminiscence of CLIPPERS. Atypical location, as here, the pons didn´t have any abnormal signal.
Brain biopsy was negative for demyelination and it showed perivascular&parenchymal lymphocytic infiltrates.
GFAP ab negative.
#neurology

[neuroimaging_neuroimmunology @NeuroimagingN]

Fulminant Multiple Sclerosis (MS)
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The patient started on high-dose steroids and plasmapheresis after week 8 but still progressed. Also received cyclophosphamide with no response either.
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Pathology of the tissue demonstrated demyelination.

#MS #Multiplesclerosis #neurotwitter

[neuroimaging_neuroimmunology @NeuroimagingN]

Hypomyelinating (dysmyelinating) leukodystrophy. Unknown mutated gene.

#Leukodystrophy #hypomyelinatingdisease #myelin #pediatricneurology #neurology #neuroradiology #radiology #NeuroTwitter #MedEd