Nichols Lab

How does the face form? Why do faces look different? We leverage the strengths of the zebrafish system to understand craniofacial development and variability.

[Development @Dev_journal]

The sclerotome is the source of the dorsal and anal fin skeleton and its expansion is required for median fin development

Read this #OpenAccess Research Article by Raisa Bailon-Zambrano, James Nichols @NicholsLab and colleagues:
https://t.co/QKTT4gNPwo

[Nichols Lab @NicholsLab]

This a special one for us, I found this weird mutant without a dorsal fin close to 15 years ago while a postdoc with Chuck Kimmel @uoregon
Ultra talented @BailonRaisa uncovered a complete story as my first PhD student. Back burner projects can pay off.
https://t.co/QgSfYZatcz

[Nichols Lab @NicholsLab]

Rae is so talented!

[Ida Chow @clawedfeet]

@SocDevBio #ChooseDev Fellow Raelyn Begay presenting her poster to judge (l) and @clawedfeet (r) @SACNAS #NDISTEM2024. Rae is recipient of a SACNAS travel award to present the poster.

[Grace Gustafson @graceinsci]

its REAL im an #nsf grfp fellow!!

[Nichols Lab @NicholsLab]

Big congratulations to Grace Gustafson for earning an NSF GRFP! She’s an outstanding scientist that really deserves this award. #creative #smart 🐟🧬#nsf #grfp @molbcu

[Nichols Lab @NicholsLab]

@CopperMtn @ColetteDolby @kmaggie337 @MorusMit @AbiMumme @WoodwardCopper

[Nichols Lab @NicholsLab]

We had a very fun lab ski day yesterday! Work hard play hard

[Nichols Lab @NicholsLab]

Join us in colorful Colorado. It’s a great place to work, and a fantastic place to live.

[CU Craniofacial, Oral and Materials Sciences @CU_COMS]

Attention craniofacial and oral biology researchers! We are looking to hire a new faculty member (at the rank of Assistant Professor) to join our collegial, research-intensive Department. Job posting: https://t.co/jGR8plSvOG

[Society for Developmental Biology @SocDevBio]

Don't miss the next #SDBPostdocSeminar this Friday, May 12 at 3pm ET featuring Elisa Zhang @ElisaTZhang from @Stanford and Stanley Michi Kanai @KanaiMichi from @CUAnschutz. Register today and join us. https://t.co/oA0OW2RUTt

[Nichols Lab @NicholsLab]

@fishyskeleton @ericliaomd @ZebrafishRock @CHOP_Research Fused otoliths too?

[Nichols Lab @NicholsLab]

Thanks to @StenzelAmanda @AbiMumme @SucharovJuliana @MorusMit @AppelLabCU for their hard work on this project. Two helpful reviewers strengthened the paper too.

[Nichols Lab @NicholsLab]

New paper from the lab. Distinct and redundant roles for zebrafish her genes during mineralization and craniofacial patterning https://t.co/QsVGH9qBzS

[Nichols Lab @NicholsLab]

Check out the remarkable mineralization phenotype in zebrafish her9 mutants: Osteoblasts develop at the correct time and place, but mineralization is only very weak, or not detectable. Cartilage is largely unaffected in mutants.

[Nichols Lab @NicholsLab]

Cheers to the best colleague anyone could ever hope for!

[Fantauzzo Lab @Fantauzzo_Lab]

Here are @NicholsLab and I celebrating our six year lab anniversary @CUAnschutz in the lovely new restaurant on campus! It's been a real pleasure navigating new PI life together.

[Nichols Lab @NicholsLab]

Yeah Julio! He has made some interesting discoveries already and will show his cool fish skeletons at the conference.

[SACNAS at CU Anschutz @SACNAS_CUA]

To start off our series, we have Julio Jaime. He is a ✨CU Denver MARC Scholar✨ and an undergraduate in the @NicholsLab. 🐟🐠🐟

[Nichols Lab @NicholsLab]

Special thanks to @SucharovJuliana for keeping this work going during the pandemic and to @BailonRaisa and @AbiMumme for seeing it through to the end!

[Nichols Lab @NicholsLab]

https://t.co/vGaM21Swjx @eLife I’m very proud of this huge team effort. Thanks to everyone who contributed, and to the editors and reviewers for a productive publishing process. @BailonRaisa @SucharovJuliana @AbiMumme @MatthewMurry @StenzelAmanda @MorusMit @ColbornKathryn

[Nichols Lab @NicholsLab]

Seeking to understand craniofacial variation we found 1) standing variation in paralog expression levels. 2) paralog expression levels are heritable 3) variation in paralog expression can modify phenotypes associated with mutation of one of the paralogs.

[Nichols Lab @NicholsLab]

Apply for this faculty position in our terrific department! Colorado is a fantastic place to live and work. https://t.co/m49Mt2vSPc

[CU Craniofacial, Oral and Materials Sciences @CU_COMS]

Attention craniofacial and oral biology researchers! We are looking to hire 1-2 faculty (at the Assistant or Associate level) to join our collegial, research-intensive Department. Job posting: https://t.co/SOOcbIqGs0