being physically or socially near the right people is a practical augmentation to your own intelligence the way people think about having frontier model access today
"The gods of most nations claim to have created the world. The Olympians make no such claim. The most they ever did was to conquer it."
Five Stages of Greek Religion, Murray, p. 46
The ability to *voluntarily* sit down and do actual work is the closest thing we have to alchemy and it is insane that people just assume it is a thing anyone can do.
In some very real sense, Ozempic was invented in 1990. Pfizer ran the human trials and just never published them.
They showed it lowered blood glucose in diabetics, slowed gastric emptying, and killed hunger; the same 3 things that make Ozempic work today.
The joint venture agreement said internal data stayed internal, and that was that. Pfizer killed the program in 1991. The reasoning, as far as I can tell, was that nobody would ever want an injectable diabetes drug besides insulin.
So, the license went back to the hospital in Boston that held the patents.
Novo picked it up in 1992 and spent the next two decades building liraglutide, then semaglutide.
It's insane that data sat in a filing cabinet for 30+ years.
I only know this because Jeffrey Flier, one of the Harvard scientists in the room, finally wrote it up. He's in his late 70s and didn't want the history to die with him.
This makes you wonder what else is in those filing cabinets.
Ozempic could've existed 27 years ago.
Christ’s gospel was so radical, so contrary to the wisdom of the world, that people are still coping 2000 years later, insisting that he didn’t actually mean what he said.
"This guy says looks are central to how you're perceived, but check out how much more attractive other people are."
so many of the dunks on this modern Icarus just embrace and reinforce his frame
Hades in Hercules (1997) has so much personality that he practically hijacks the entire movie. James Woods delivering every line at machine-gun speed like an exhausted Hollywood agent trapped in Greek mythology was such a great choice.
The “succulent Chinese meal” dude is the closest we have to a living breathing realisation of Nietzsche’s Ubermensch. A man who has transcended morality and resentment and survey the affairs of mere men with a haughty detachment and much laughing.