I just released ReShiki v0.6.1, a free, open-source alternative to ChemDraw.
Chemical drawing, reinvented.
Built in Rust for macOS, Windows, and Linux. Draw molecules, build reaction schemes, and export figures.
Try it: https://t.co/CrYQ1alzHT
Our new paper is out in Org Lett! We continue to find new applications for our alcohol oxidase. This time, we've combined it with an ERED to make (R)-citronellal from geraniol. A very special collab with Caroline’s group. Great teamwork! https://t.co/8xNjJ9z08x
@OmarartoOAS@Sigman_Lab So proud of having supervised your outstanding work during this and the other projects that will make up your PhD dissertation #proudsupervisor
My second firts-author publication and my introduction to the Predictive Statistical Analysis field, which we used to further study our Gold(I) Catalyzed Cycloisomerization of 1-Bromoalkynes. I'm also really looking forward to sharing the upcoming work of @PbLabUniOvi!! (2/2)
I'm really excited to start a new academic year and looking back on our last one, I'm incredibly proud of the work behind our collaboration with @Sigman_Lab as well as the dedication and involvement of all the authors. (1/2) https://t.co/oy2fKugwks
Our latest work on the silyl radical generation, Direct-Excitation-Enabled Radical Hydrosilylation via a Silyl Radical Precursor | Organic Letters https://t.co/k80KlDaEpC
Honored to see two of our recent @JOC_OL publications among the most read this month!! Check them out in the following post(I also leave the link of our third OL this month, which will appear back-to-back with the second one). Thanks to the readers of @JOC_OL for the interest
Extending this study to terpene-derived trisubstituted systems, we discovered a new reaction pathway: a 5-exo-dig process on unactivated C–H bonds, not previously observed in this context.
https://t.co/NSDCFGKeRj
We are excited to share our two back-to-back papers in @JOC_OL! 🚀 We studied how conformations affect the cycloisomerization of 1-bromoalkynes, highlighting the key role of a methyl group on the cyclohexane ring. https://t.co/jcnPEO2DtO
Again, thanks to @PabloBarrioChem for the opportunity, to Dr. Merino for the meticulous NMR characterization, and the Haberhauer team for the calculations. Special thanks to @MorenRmm for his enormous contribution — check his profile for more details!!!✨(4/4)
✨I'm also very happy to announce that the second part of our study is out now in @JOC_OL!!✨ Herein we present an overview of how conformational effects influence the outcome of our gold(I)-catalyzed cycloisomerization of 1-Bromoalkynes. (1/4) https://t.co/PDvvldGUIf
This 5-exo-dig transformation shows some really interesting features which are currently being studied at @PbLabUniOvi. We are so excited to share our work with the community. Please, stay tuned to find out more about these powerful transformations!!!✨(3/4)
Thanks to @PabloBarrioChem for the opportunity to join this project. Also thanks to Dr. Merino for the meticulous NMR characterization and the Haberhauer team for the calculations. Special thanks to @MorenRmm for his enormous contribution! Check his profile for more details!(3/3)
🎉Our new scientific contribution is out now!!🎉Herein we present an overview of how the conformational effects affect the outcome of our gold(I)-catalyzed cycloisomerizarion of 1-Bromoalkynes. (1/3)
https://t.co/YHb0LkbxSX
By placing aliphatic substituents at all positions of the cyclohexane ring, we can analyze the intrinsic conformational effects and their impact on a C–H functionalization process. All of this is supported by DFT calculations to help rationalize the observed results. (2/3)
🎉 Good news! Our latest work has just been published in @JOC_OL. In this study, we focused on the conformational effects in the cycloisomerization of 1-bromoalkynes under gold(I) catalysis. A perfect playground to see how small changes reshape outcomes. https://t.co/tiAqlbzckn
My first work with anomeric amides has just been published in @Synthesis_1969! Thanks to all collaborators, especially Julia and Mark. We report new derivatives with faster kinetics and higher yields, providing insight into stereoelectronic effects in nitrogen-deletion reactions.