Open Source Neuro

Developing open source hardware for neuroscience research and education

[Open Source Neuro @OpenSourceNeuro]

For this new year, we are proud to announce the launch of Spikeling v3 !
Spikeling is an Open-Source neuroscience education platform that brings a patch-clamp-style electrophysiology workflow into the classroom. #Neuroscience #OpenScience #OpenHardware #Education

[Open Source Neuro @OpenSourceNeuro]

The idea in this part 3 is to introduce that neuronal network architecture matters to solve boolean operations at different degrees !

#NeuralNetworks #MachineLearning #DeepLearning

[Open Source Neuro @OpenSourceNeuro]

Neuronal logic with Spikeling ! Part 3

Spikeling is a virtual spiking neuron you can patch and tune. It’s a brilliant bridge between neuroscience, boolean logic, and machine learning fundamentals.

#Neuroscience #ComputationalSciences #Neurophysiology #Electrophysiology

[Open Source Neuro @OpenSourceNeuro]

Spikeling is such a powerful teaching tool since it makes abstract ideas in neuroscience, maths, and computational science visible with hands-on experience on synaptic weights, integration, and decision boundaries.

#STEMEducation #SystemsNeuroscience

[Open Source Neuro @OpenSourceNeuro]

Spikeling helps make these principles tangible, linking neurophysiology, electronics, and computational neuroscience through hands-on experiments.
#ArtificialNeuralNetworks #STEMEducation #OpenScience

[Open Source Neuro @OpenSourceNeuro]

Neuronal logic with Spikeling: part 2

In part 1, we showed how to build OR and AND gates for action potentials using excitatory synaptic gains.

#Neuroscience #Neurophysiology #Electrophysiology #NeuralCircuits

[Open Source Neuro @OpenSourceNeuro]

It is fascinating to see how modulation of synaptic strength can gate information flow in neural circuits. This also echoes a core idea in artificial neural networks, where weights determine how strongly signals influence downstream units.
#MachineLearning #AI

[Open Source Neuro @OpenSourceNeuro]

Yesterday was #purpleday, the global epilepsy awareness day. Learn about mechanisms of seizure occurence in epilepsy with a 2-minutes Spikeling workshop ! #Neuroscience #Education #Epilepsy

[Open Source Neuro @OpenSourceNeuro]

See how we can approach the mechanisms of seizure occurence in epilepsy with a 2-minutes Spikeling workshop ! #Epilepsy #Seizure #Neuroscience #Electrophysiology #Neurophysiology

[Open Source Neuro @OpenSourceNeuro]

See how we explore neuronal logic with a quick Spikeling circuit workshop — Part 1. #LogicalGating

[Open Source Neuro @OpenSourceNeuro]

Neural computation emerges from physical processes in biological circuits.

#Neuroscience #ComputerScience #NeuronalCircuits

[Open Source Neuro @OpenSourceNeuro]

Spikeling brings these core principles of neuronal computation, at the intersection of neurophysiology and computer science.

[Open Source Neuro @OpenSourceNeuro]

- to offer hands-on experience to the whole classroom, instead of just for a few students lucky enough to get an internship with wet-lab experience. #CalciumImaging

[Open Source Neuro @OpenSourceNeuro]

Yesterday for @OpenSourceNeuro, Paul Rignanese was presenting a poster and a live demo of Spikeling at the Institute for Neuroscience and Cardiovascular Research Early Career Researcher Day at the The @EdinburghUni !

#Neuroscience #BiomedicalSciences

[Open Source Neuro @OpenSourceNeuro]

We hope to integrate Spikeling workshops as a complement to electrophysiology lectures in neuroscience and biomedical sciences programs -

[Open Source Neuro @OpenSourceNeuro]

- Signal preprocessing, see how to handle different types of noise and cleanup your data before extracting spikes.

Stay tuned for advancements ! #Neuropixel

[Open Source Neuro @OpenSourceNeuro]

Spikeling v3 feature reveal : a new module ! After current clamp, voltage clamp, calcium imaging, we are implementing an extracellular tetrode recording module ! #Neuroscience #CalciumImaging

[Open Source Neuro @OpenSourceNeuro]

See how your Spikeling neuron firing action potentials would look like in a extracellular ephys setup live. Features :

- Spatial integration, see how the electrode placement relative to the neuron impacts the extracellular field recordings, determining for spike sorting. #Ephys