I am so happy to be part of EMBO. Europe has made many things possible throughout my career from postdoctoral training to senior faculty. Grateful supports from WT, ERC, OeAW and others. Fantastic collaborations with many friends! Truly miss my time there. Thank you all!
We are excited to report the discovery of TIGRs, a widely-occurring RNA-guided system found in bacteria and their viruses. TIGRs consist of a peculiar repeat region which is transcribed into RNA and processed into multiple guide RNAs to direct TIGR-associated proteins to their DNA targets. https://t.co/ketXqFVQqw
Scientists described for the first time the mechanisms underlying a class 2 mutation using #photoreceptor precursors and retinal #organoids from patient-derived stem cells. 👁️🧫
https://t.co/lOdcT7atN1
For some time now we’ve been aware that Chiron #gastruloids, while representing well axial elongation, exhibit a shortage of anterior fates. Here https://t.co/VyvomYxTJT led by @_andre_Dias_ we uncover the reason
The Genome India Project offers us 10,000 genomes that represent the 4 broad linguistic groups, and regions across India incl tribal populations. They are available at the Indian Biological Data Centre at RCB, Faridabad for academics to analyze and unveil mysteries held in them.
HYL001 is a TGF-beta signaling inhibitor structurally related to galunisertib (LY2157299), yet shows around 9x increased potency in “in vivo” pre-clinical models of advanced colorectal #cancer
👉🏻https://t.co/QxEfvNlimV
I am looking for a postdoc candidate, who can work with us using our mosaic genetics tools. All mouse lines are ready for you and there are many exciting projects ready to work on immediately. Email me: [email protected]#Koo_lab
An example project: https://t.co/0t2ZQj9EET
[Reprogramming & Regeneration] Another one in the same journal on the same day. I am so happy to introduce this collaboration with Prof Cha at the Seoul National Univ. We found that Yamanaka factors can trigger the same regenerative pools in the intestine. https://t.co/7AS9sLtgnN
Very good interview w/ @jacob_hanna on #Stemcell human #EmbryoModels in today’s @BBCWorldatone series on 'Fertility and the future of the family" https://t.co/Oho5qamtC6 from min34
No misrepresentations, no exaggerated headlines. Good explanations of whats, whys & hows.
#helpful
After building embryoids for 10 years, we succeeded in generating structures with brains, hearts, neural tubes, somites with a yolk sac. Both original submissions using two different approaches are on BioRxiv, to be published soon. https://t.co/p1ZL2C3UPH