Post Orgasmic illness Syndrome

Channel dedicated to POIS

[Post Orgasmic illness Syndrome @Orgasmicillness]

POIS paper archive
https://t.co/rRkgHKgj2q
POIS paper treatment
https://t.co/hxnFWFxbTc
POIS treatment community
https://t.co/8thK5JqewZ
List of Doctors
https://t.co/pbcHPd8ZlR
List of theories
https://t.co/puwhVjGbRX
Newcomer's thread
https://t.co/PmPqkzt0IE

[Post Orgasmic illness Syndrome @Orgasmicillness]

@robertjohnsoncr @NicoleRPrause No

[Nicole Prause @NicoleRPrause]

If you know a man who struggles with flu-like symptoms after climax, we are recruiting for patients experiencing post-orgasmic illness syndrome!
https://t.co/chqgV0uZEW

[Nicole Prause @NicoleRPrause]

We are n=49 in our male orgasm study.
These data are looking so clean!
Galvanic skin response (from foot)
Pneumatic response (from anus)
Temperature (from neck)

[Nicole Prause @NicoleRPrause]

I am so excited about these data. Another male showing a drop in SNS pre-climax.
I'm getting more and more confident we are going to revise the Masters and Johnson model of sexual response...
but we have n=51 more to go!

[Nicole Prause @NicoleRPrause]

We are still looking for patients with the rare disorder post-orgasmic illness syndrome (POIS) for a laboratory study in Los Angeles!
https://t.co/chqgV0uZEW

[Nicole Prause @NicoleRPrause]

New equipment day!
We are crawling to the halfway recruitment point of the male response study...

[Nicole Prause @NicoleRPrause]

This might be the most beautiful temperature plot to date in our male orgasm study.
It is very rare to have a human body responding in such a clear pattern!
The first jump is when manual stimulation starts (~1,100).

[Nicole Prause @NicoleRPrause]

"Dr. Lorenz does fluids, I do electrical"
- a completely accurate statement about our study of male orgasm physiology

[Nicole Prause @NicoleRPrause]

We have n=43 male climax in the lab, and the traces are gorgeous!
This shows about 18 contractions, an outlier from the 8-12 contractions described at "typical" in research from the 1980's.

[Nicole Prause @NicoleRPrause]

I am loving these data! n=42
More evidence of male sexual flushing.

[Nicole Prause @NicoleRPrause]

If you know men in Los Angeles struggling with post-orgasmic illness syndrome (POIS), please consider sharing this research opportunity with them!

[Nicole Prause @NicoleRPrause]

We have n=41 in our male orgasm lab study at UCLA!
On the way to n=100 and the largest of its kind.
I can't wait to share those data...

[Post Orgasmic illness Syndrome @Orgasmicillness]

https://t.co/JZDE1AylRR @NicoleRPrause 🤔

[Nicole Prause @NicoleRPrause]

https://t.co/chqgV0uZEW

[Nicole Prause @NicoleRPrause]

@zoref07 Data collection will probably go on at least 6 more months. We will be presenting interim results at conferences before papers start to go in.
Science is slow...and careful.

[Nicole Prause @NicoleRPrause]

Our study on UCLA campus is almost done recruiting for open volunteers (before we start looking for patients).
If you have an interest and are in Los Angeles, you can find out if you are qualified and/or volunteer here:
https://t.co/chqgV0urPo

[Ahmet Tevfik Albayrak | Urological Surgeon @ahmettevfikal]

Excited to share our study on the consistency of artificial intelligence in Post-Orgasmic Illness Syndrome (POIS), presented at #SMSNA2025. #SMSNA2025 #POIS #ArtificialIntelligence #Andrology #SexualMedicine #MensHealth #Innovation

[Nicole Prause @NicoleRPrause]

Three more samples and they're on their way to the lab on dry ice for testing!

[Nicole Prause @NicoleRPrause]

Ready.
Set.
Go!

[Nicole Prause @NicoleRPrause]

LET'S GO SCIENCE
n=18 on the way to 100
These are three hour lab protocols with extensive setup/clean up, so we are plodding along.