OxAMI - Oxford Acute Myocardial Infarction Study

[Rafail Kotronias @RafKotronias]

1/ Background
🚫Current guidelines discourage CCTA in elderly patients or those with heavy coronary calcification due to reduced accuracy.
🔬 Photon-Counting CCTA (PCCTA)—offers ultrahigh resolution & multi-energy imaging.
💡But does it solve the calcification problem?

[Rafail Kotronias @RafKotronias]

📢 Tweetorial: Can Photon-Counting CCTA (PCCTA) Overcome Heavy Coronary Calcification? 🫀📸https://t.co/QYiSTzz6UB
A deep dive into how ultrahigh-resolution PCCTA (UHR-PCCTA) and standard resolution PCCTA (SR-PCCTA) stack up against gold-standard 3D invasive QCA.🧵👇🧵👇

[Mayooran Shan @MayooranShan]

Proud to have published this paper from @OxAMI_Study in @JACCJournals.

#whyCMR performed before invasive coronary angiogram may change management in ~50% of the patients admitted to hospital with suspected #NSTEMI

https://t.co/wSBOnj0XH8

@TheBHF : https://t.co/uJChUjAgHE

[Leonardo Portolan @MdLPortolan]

Angiography-derived IMR to predict early cardiovascular complications after STEMI and define the risk of early discharge!
Read our paper on @CircIntv !
https://t.co/1rqTJPJGqT
@MdScarsini @GiovanniLuigiD1 @RafKotronias @BenenatiStefano

[Mayooran Shan @MayooranShan]

Our new paper from the @OxAMI_Study @RDMOxford @OUHospitals in @JACCJournals https://t.co/O4NirfVZsW

Whole heart #whyCMR #T1mapping in #STEMI shows that acute adverse response in the non-infarcted myocardium is associated with the development of #heartfailure at long-term

🧵

[Circulation @CircAHA]

#OriginalResearch: #AI-based Virtual Native Enhancement is a contrast-free MRI alternative to LGE for tissue characterization in patients with prior #MI. @QiangZhangAiCmr @DrMattBurrage @mayooranshan @_ragonzales#AHAJournals https://t.co/B2tyJqx6tc

[Mayooran Shan @MayooranShan]

Proud to have contributed to this work with colleagues from @RDMOxford in @OxAMI_Study

Contrast-free assessment of scar in chronic myocardial infarction using cine imaging and T1-mapping.

@BHFT @OxfordBRC @lmhoxford

#faster #whyCMR #ArtificialIntelligence
@SCMRorg @BSCMR

[Rafail Kotronias @RafKotronias]

🚨💫Interventional 🫀 Research Fellowship opportunity @UniofOxford @OxAMI_Study programme working closely with @GiovanniLuigiD1 & Prof Banning.
Open to clinicians of any grade @TheBJCA @BJCAstarter
Fore more info: 👇 DMs for more ℹ️ welcome.🚨
https://t.co/lxVw6hHsl9

[Mayooran Shan @MayooranShan]

Congrats to @NavAkbar and @Choudhury_Lab for this work showing a mechanism behind the innate immune response post-MI. Pleasure to have contributed to this project via @OxAMI_Study
#CardioTwitter @ESC_Journals

[Rafail Kotronias @RafKotronias]

(5/6) Future outlook
NH IMRangio can:

📈 adoption of coronary microvascular function assessment in STE-ACS
✅risk stratify patients with STE-ACS
✅be deployed to triage 1) adjunct therapies and 2) dedicated treatment pathways for STE-ACS care

[Rafail Kotronias @RafKotronias]

(4/6) Summary results
NH IMRangio is:
✅Diagnostically reliable compared to IMR ✅Prognostically equivalent to IMR
✅Independent predictor of an adverse outcome

[Rafail Kotronias @RafKotronias]

(3/6)
-IMRangio was computed using the @MedisImaging
QFR platform as recently demonstrated in our live webinar 👉 https://t.co/qL2ougiWDi
-Methodology and validation are described in detail in our previous papers https://t.co/hu5eY3LhDh & https://t.co/0Vb6PMRlfy @IntJCVImaging

[Rafail Kotronias @RafKotronias]

(1/6) Breaking @FrontCVMedicine! Non-hyperemic angiography-derived IMR is prognostically equivalent to IMR for long-term adverse outcomes in STE-ACS. First 🥇head to head study in the field by our team https://t.co/oUuAi6ZHNJ @PCRonline @BCIS_uk @TCTMD #PCI #CoronaryIntervention

[Rafail Kotronias @RafKotronias]

Proud to have presented at the #EuroPCR @PCRonline Late Breaking Trials Session my work on angiography-derived IMR (IMRangio) to predict long-term outcome in STEMI in the OxAMI @OxfordBRC 👉https://t.co/KTltiHKt46

[Rafail Kotronias @RafKotronias]

Our full paper with @GiovanniLuigiD1 @hect2701 @dterentes @MayooranShan @MarinF_MD @MdScarsini @james_bw19 is now available online @FrontCVMedicine under an open access agreement. Download 👉https://t.co/oUuAi6ZHNJ Separate tweetorial to follow 👏

[Giovanni Luigi De Maria @GiovanniLuigiD1]

Great webinar on #QFR in coronary artery disease in AVIC-Oxford Heart Centre. Massive thanks to prof Banning and all fellows involved in this educational event @MedisImaging @MdScarsini @RafKotronias @dterentes @MarinF_MD @MdMontalto @MayooranShan @MEmfietzoglou

[Mayooran Shan @MayooranShan]

An excellent editorial review (with very valid added suggestions) on @OxAMI_Study paper we recently published.

https://t.co/zCtCO0w6Zo

Coronary Microvascular Dysfunction Assessed by Pressure Wire and CMR A... https://t.co/aCvOImMqiI

@MdScarsini @GiovanniLuigiD1 @RafKotronias